New knock-in mouse lines <i>Dmp1<sup>em1(CreERT2)</sup></i> and <i>Dmp1<sup>em2(ZsGreen)</sup></i> enable precise osteocyte-specific targeting and visualization. [PDF]
JBMR PlusHu YJ +5 more
europepmc +1 more source
Cell Therapy for Periodontal, Soft‐Tissue, and Craniofacial Regeneration
Journal of Periodontal Research, EarlyView.The clinical translation of mesenchymal stem/stromal cells (MSCs) represents a major advancement in dentistry, especially for periodontal, soft‐tissue, and craniofacial regeneration. However, several challenges remain to be addressed, including the absence of standardised protocols, limited scalability, regulatory hurdles, a lack of well‐controlled ...
Kamal Mustafa +5 more
wiley +1 more source
<i>Thra</i> knockout protects male mice from hyperthyroidism-driven cortical bone loss by mitigating bone resorption. [PDF]
JBMR PlusBrinkmann F +5 more
europepmc +1 more source
Experiment K-6-03. Gravity and skeletal growth, part 1. Part 2: Morphology and histochemistry of bone cells and vasculature of the tibia; Part 3: Nuclear volume analysis of osteoblast histogenesis in periodontal ligament cells; Part 4: Intervertebral disc swelling pressure associated with microgravity [PDF]
Bone area, bone electrophysiology, bone vascularity, osteoblast morphology, and osteoblast histogenesis were studied in rats associated with Cosmos 1887.
Berretta, D. +9 more
core +1 more source
Journal of Periodontal Research, EarlyView.A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed +6 more
wiley +1 more source
Impaired bone matrix maturation and mineralization are prevalent in adolescent end-stage kidney disease. [PDF]
JBMR PlusFratzl-Zelman N +6 more
europepmc +1 more source
Journal of Periodontal Research, EarlyView.NF‐κB/FOXO3a/c‐JUN pathway plays a crucial role in osteogenic. Differentiation of aged PDLCs in an inflammatory microenvironment, although the mechanisms of this pathway differ in cellular ageing and pathological inflammation. ABSTRACT Aim This study aims to investigate the effect of inflammation on the senescence phenotype and osteogenic capacity of ...
Luying Zhu +6 more
wiley +1 more source
Modulation of tocotrienol's bone effects by osteocytes: a perspective. [PDF]
Front PharmacolZahanordin NN, Ng PY, Chin KY.
europepmc +1 more source
Inflammatory and Immunological Basis of Periodontal Diseases
Journal of Periodontal Research, EarlyView.The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima +3 more
wiley +1 more source
Osteocytes orchestrate browning: emerging signals in bone-fat crosstalk: a systematic review. [PDF]
Front Endocrinol (Lausanne)Anees H +6 more
europepmc +1 more source