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Current Osteoporosis Reports, 2003
The osteocyte is the most abundant cell type of bone. There are approximately 10 times as many osteocytes as osteoblasts in adult human bone, and the number of osteoclasts is only a fraction of the number of osteoblasts. Our current knowledge of the role of osteocytes in bone metabolism is far behind our insight into the properties and functions of the
Klein Nulend, J. +2 more
openaire +3 more sources
The osteocyte is the most abundant cell type of bone. There are approximately 10 times as many osteocytes as osteoblasts in adult human bone, and the number of osteoclasts is only a fraction of the number of osteoblasts. Our current knowledge of the role of osteocytes in bone metabolism is far behind our insight into the properties and functions of the
Klein Nulend, J. +2 more
openaire +3 more sources
Mechanisms of Osteocyte Mechanotransduction
Clinical Reviews in Bone and Mineral Metabolism, 2010Healthy bones combine a proper resistance against fracture with a minimum use of material. This property is likely brought about by osteocytes in response to mechanical cues, but it is still unknown how whole bone loads are translated into a signal that can be sensed by the osteocytes.
Bakker, A.D., Klein Nulend, J.
openaire +4 more sources
Role of Osteocytes in Cancer Progression in the Bone and the Associated Skeletal Disease
Current Osteoporosis Reports, 2021Jesus Delgado-Calle +1 more
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