Results 1 to 10 of about 138,357 (192)
Role of galectin-3 in bone cell differentiation, bone pathophysiology and vascular osteogenesis [PDF]
International Journal of Molecular Sciences, 2017 Galectin-3 is expressed in various tissues, including the bone, where it is considered a marker of chondrogenic and osteogenic cell lineages. Galectin-3 protein was found to be increased in the differentiated chondrocytes of the metaphyseal plate ...
Fantauzzi, Claudia Blasetti +3 more
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Multi-omics identification of key targets for the osteogenic differentiation of human bone marrow mesenchymal stromal cells under oxidative stress [PDF]
Scientific ReportsHuman bone marrow mesenchymal stromal cells (hBMSCs) are multipotent stromal cells capable of osteogenic differentiation, making them a promising cell source for bone tissue engineering and regenerative medicine.
Wentao Dong +11 more
doaj +2 more sources
Patterned Piezoelectric Scaffolds for Osteogenic Differentiation [PDF]
International Journal of Molecular Sciences, 2020 The morphological clues of scaffolds can determine cell behavior and, therefore, the patterning of electroactive polymers can be a suitable strategy for bone tissue engineering. In this way, this work reports on the influence of poly(vinylidene fluoride-co-trifluoroethylene) (P(VDF-TrFE)) electroactive micropatterned scaffolds on the proliferation and ...
Teresa Marques-Almeida +4 more
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Icariin promotes osteogenic differentiation by upregulating alpha-enolase expression
Biochemistry and Biophysics Reports, 2023 Osteogenic differentiation is a crucial biological process for maintaining bone remodelling. Aerobic glycolysis is the main source of energy for osteogenic differentiation.
Dingbang Xie +8 more
doaj +1 more source
Bisindoylmaleimide I enhances osteogenic differentiation [PDF]
Protein & Cell, 2012 The Wnt/β-catenin and bone morphogenetic proteins (BMPs) pathways play important roles in controlling osteogenesis. Using a cell-based kinase inhibitor screening assay, we identified the compound bisindoylmaleimide I (BIM) as a potent agonist of the cytosolic β-catenin accumulation in preosteoblast cells. Through suppressing glycogen synthase kinase 3β
Zhou, F.F., Huang, H.Z., Zhang, L.
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Histone modifications centric-regulation in osteogenic differentiation [PDF]
Cell Death Discovery, 2021 AbstractHistone modification critically contributes to the epigenetic control of gene expression by changing the configuration of chromatin and modifying the access of transcription factors to gene promoters. Recently, we observed that histone acetylation and crotonylation mediated the expression of endocytosis-related genes and tumor-related immune ...
Kun Li, Jinxiang Han, Ziqiang Wang
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Arthritis Research & Therapy, 2022 Background Bone marrow-derived mesenchymal stem cells (BMSCs) are general progenitor cells of osteoblasts and adipocytes and they are characterized as a fundamental mediator for bone formation.
Lixia Fan +4 more
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Journal of Dental Sciences, 2023 Background/purpose: Human dental pulp stem cells (hDPSCs) possess excellent proliferative and osteogenic differentiation potentials. This study aimed to elucidate the role of lysophosphatidic acid (LPA) signaling in the proliferation and osteogenic ...
Soon Chul Heo +8 more
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The Regulatory Landscape of Osteogenic Differentiation [PDF]
Stem Cells, 2014 AbstractDifferentiation of osteoblasts from mesenchymal stem cells (MSCs) is an integral part of bone development and homeostasis, and may when improperly regulated cause disease such as bone cancer or osteoporosis. Using unbiased high-throughput methods we here characterize the landscape of global changes in gene expression, histone modifications, and
Anne-Mari, Håkelien +8 more
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Involvement of the long noncoding RNA H19 in osteogenic differentiation and bone regeneration
Stem Cell Research & Therapy, 2021 Osteogenic differentiation and bone regeneration are complex processes involving multiple genes and multiple steps. In this review, we summarize the effects of the long noncoding RNA (lncRNA) H19 on osteogenic differentiation.
Zimo Zhou +2 more
doaj +1 more source