Results 1 to 10 of about 148,060 (339)

Enhanced osteogenic differentiation in zoledronate-treated osteoporotic patients [PDF]

International Journal of Molecular Sciences, 2017
Bisphosphonates are well known inhibitors of osteoclast activity and thus may be employed to influence osteoblast activity. The present study was designed to evaluate the in vivo effects of zoledronic acid (ZA) on the proliferation and osteoblastic ...
Carbonare, Luca Dalle, Dellantonio, Alessandra, Malerba, Giovanni, Mori, Antonio, Mottes, Monica, Plebani, Mario, Valenti, Maria Teresa, Zaninotto, Martina   +7 more
core   +9 more sources

A roadmap of osteogenic differentiation in human mesenchymal stem cells assessed by protein multiplex analysis

European Cells & Materials
Human mesenchymal stem cells (hMSCs) are widely used to model osteogenic differentiation in vitro, yet few studies compare the numerous available protocols.
M Eischen-Loges, Z Tahmasebi Birgani, Y Alaoui Selsouli, L Eijssen, H Rho, M Sthijns, M van Griensven, V LaPointe, P Habibović   +8 more
doaj   +2 more sources

Similarity-based metric analysis approach for predicting osteogenic differentiation correlation coefficients and discovering the novel osteogenic-related gene FOXA1 in BMSCs [PDF]

PeerJ
Background As a powerful tool, bioinformatics analysis is playing an increasingly important role in many fields. Osteogenic differentiation is a complex biological process involving the fine regulation of numerous genes and signaling pathways.
Lingtong Sun, Juan Chen, Li Jun Li, Lingdi Li   +3 more
doaj   +3 more sources

Icariin promotes osteogenic differentiation by upregulating alpha-enolase expression

Biochemistry and Biophysics Reports, 2023
Osteogenic differentiation is a crucial biological process for maintaining bone remodelling. Aerobic glycolysis is the main source of energy for osteogenic differentiation.
Dingbang Xie, Yunteng Xu, Wanping Cai, Junkuan Zhuo, Zaishi Zhu, Haifeng Zhang, Yimin Zhang, Xin Lan, Hui Yan   +8 more
doaj   +1 more source

Murine and human myogenic cells identified by elevated aldehyde dehydrogenase activity: Implications for muscle regeneration and repair [PDF]

, 2011
Background: Despite the initial promise of myoblast transfer therapy to restore dystrophin in Duchenne muscular dystrophy patients, clinical efficacy has been limited, primarily by poor cell survival post-transplantation. Murine muscle derived stem cells
Bucsek, MJ, Huard, J, Song, M, Thompson, SD, Vella, JB   +4 more
core   +15 more sources

circ-Iqsec1 induces bone marrow-derived mesenchymal stem cell (BMSC) osteogenic differentiation through the miR-187-3p/Satb2 signaling pathway

Arthritis Research & Therapy, 2022
Background Bone marrow-derived mesenchymal stem cells (BMSCs) are general progenitor cells of osteoblasts and adipocytes and they are characterized as a fundamental mediator for bone formation.
Lixia Fan, Kaiyun Yang, Ruixuan Yu, Houde Hui, Wenliang Wu   +4 more
doaj   +1 more source

Lysophosphatidic acid induces proliferation and osteogenic differentiation of human dental pulp stem cell through lysophosphatidic acid receptor 3/extracellular signal-regulated kinase signaling axis

Journal of Dental Sciences, 2023
Background/purpose: Human dental pulp stem cells (hDPSCs) possess excellent proliferative and osteogenic differentiation potentials. This study aimed to elucidate the role of lysophosphatidic acid (LPA) signaling in the proliferation and osteogenic ...
Soon Chul Heo, Bo Ram Keum, Eun Jin Seo, Jinhwan Yoon, Sanghwa Jeong, Gabor J. Tigyi, Derek Norman, Il Ho Jang, Hyung Joon Kim   +8 more
doaj   +1 more source

Involvement of the long noncoding RNA H19 in osteogenic differentiation and bone regeneration

Stem Cell Research & Therapy, 2021
Osteogenic differentiation and bone regeneration are complex processes involving multiple genes and multiple steps. In this review, we summarize the effects of the long noncoding RNA (lncRNA) H19 on osteogenic differentiation.
Zimo Zhou, Mohammad Showkat Hossain, Da Liu   +2 more
doaj   +1 more source

Mechanical Sensing Element PDLIM5 Promotes Osteogenesis of Human Fibroblasts by Affecting the Activity of Microfilaments

Biomolecules, 2021
Human skin fibroblasts (HSFs) approximate the multidirectional differentiation potential of mesenchymal stem cells, so they are often used in differentiation, cell cultures, and injury repair. They are an important seed source in the field of bone tissue
Xiaolan Huang, Rongmei Qu, Yan Peng, Yuchao Yang, Tingyu Fan, Bing Sun, Asmat Ullah Khan, Shutong Wu, Kuanhai Wei, Chujiang Xu, Jingxing Dai, Jun Ouyang, Shizhen Zhong   +12 more
doaj   +1 more source

Probing Notch1-Dll4 signaling in regulating osteogenic differentiation of human mesenchymal stem cells using single cell nanobiosensor

Scientific Reports, 2022
Human mesenchymal stem cells (hMSCs) have great potential in cell-based therapies for tissue engineering and regenerative medicine due to their self-renewal and multipotent properties.
Yuwen Zhao, Rui Yang, Zoe Bousraou, Kiarra Richardson, Shue Wang   +4 more
doaj   +1 more source