Results 21 to 30 of about 148,060 (339)

RUNX3 derived hsa_circ_0005752 accelerates the osteogenic differentiation of adipose-derived stem cells via the miR-496/MDM2-p53 pathway

Regenerative Therapy, 2021
Background: Circular RNAs (circRNAs) are non-coding RNAs that play a pivotal role in bone diseases. RUNX3 was an essential transcriptional regulator during osteogenesis.
Ming Wang, Yifan Huan, Xiyang Li, Jing Li, Guohua Lv   +4 more
doaj   +1 more source

Osteogenic Differentiation of Dental Follicle Stem Cells [PDF]

International Journal of Medical Sciences, 2012
Stem cells are defined as clonogenic cells capable of self-renewal and multi-lineage differentiation. A population of these cells has been identified in human Dental Follicle (DF). Dental Follicle Stem Cells (DFSCs) were found in pediatric unerupted wisdom teeth and have been shown to differentiate, under particular conditions, into various cell types ...
Mori G, Ballini A, Carbone C, Oranger A, Di Benedetto A, Rapone B, Cantore S, BRUNETTI, GIACOMINA, DI COMITE, Mariasevera, COLUCCI, Silvia Concetta, GRANO, Maria, GRASSI, Felice Roberto   +11 more
openaire   +3 more sources

Bioactive sphene-based ceramic coatings on cpTi substrates for dental implants: An in vitro study [PDF]

, 2018
Titanium implant surface modifications have been widely investigated to favor the process of osseointegration. The present work aimed to evaluate the effect of sphene (CaTiSiO5) biocoating, on titanium substrates, on the in vitro osteogenic ...
Badocco, Denis, Biasetto, Lisa, Brunello, Giulia, Elsayed, Hamada, Ferroni, Letizia, Gardin, Chiara, Pastore, Paolo, Sivolella, Stefano, Zavan, Barbara   +8 more
core   +2 more sources

Expression of fibroblast growth factor receptor and its role in regulating osteoblast differentiation

Di-san junyi daxue xuebao, 2019
Objective To investigate the changes in the expression of fibroblast growth factor receptors 1-3 (FGFR1-3) at different stages of osteogenic differentiation and clarify the role of FGFR signaling in osteogenic differentiation.
MO Qifei, YANG Peng, SU Nan, CHEN Lin
doaj   +1 more source

BRD4 facilitates osteogenic differentiation of human bone marrow mesenchymal stem cells through WNT4/NF-κB pathway

Journal of Orthopaedic Surgery and Research, 2023
Background Human bone marrow mesenchymal stem cells (hBMSCs) are a major source of osteoblast precursor cells and are directly involved in osteoporosis (OP) progression.
Tao Ning, Huihui Guo, Mingming Ma, Zhengang Zha   +3 more
doaj   +1 more source

Adipokines regulate mesenchymal stem cell osteogenic differentiation

World Journal of Stem Cells, 2023
Mesenchymal stem cells (MSCs) can differentiate into various tissue cell types including bone, adipose, cartilage, and muscle. Among those, osteogenic differentiation of MSCs has been widely explored in many bone tissue engineering studies. Moreover, the conditions and methods of inducing osteogenic differentiation of MSCs are continuously advancing ...
Xu, Zhong-Hua, Xiong, Chen-Wei, Miao, Kai-Song, Yu, Zhen-Tang, Zhang, Jun-Jie, Yu, Chang-Lin, Huang, Yong, Zhou, Xin-Die   +7 more
openaire   +2 more sources

Detection of early osteogenic commitment in primary cells using Raman spectroscopy [PDF]

, 2017
Major challenges in the development of novel implant surfaces for artificial joints include osteoblast heterogeneity and the lack of a simple and sensitive in vitro assay to measure early osteogenic responses.
Clarkin, C E, Emery, R, Mahajan, S, Pitsillides, A A, Smith, S J   +4 more
core   +1 more source

Effects of Extracellular Vesicles from Osteogenic Differentiated Human BMSCs on Osteogenic and Adipogenic Differentiation Capacity of Naïve Human BMSCs

Cells, 2022
Osteoporosis, or steroid-induced osteonecrosis of the hip, is accompanied by increased bone marrow adipogenesis. Such a disorder of adipogenic/osteogenic differentiation, affecting bone-marrow-derived mesenchymal stem cells (BMSCs), contributes to bone ...
Chenglong Wang, Sabine Stöckl, Shushan Li, Marietta Herrmann, Christoph Lukas, Yvonne Reinders, Albert Sickmann, Susanne Grässel   +7 more
doaj   +1 more source

Osteogenic differentiation of fibroblast-like synovial cells in rheumatoid arthritis is induced by microRNA-218 through a ROBO/Slit pathway

Arthritis Research & Therapy, 2018
Background Fibroblast-like synovial cells (FLS) have multilineage differentiation potential including osteoblasts. We aimed to investigate the role of microRNAs during the osteogenic differentiation of rheumatoid arthritis (RA)-FLS.
Naoki Iwamoto, Shoichi Fukui, Ayuko Takatani, Toshimasa Shimizu, Masataka Umeda, Ayako Nishino, Takashi Igawa, Tomohiro Koga, Shin-ya Kawashiri, Kunihiro Ichinose, Mami Tmai, Hideki Nakamura, Tomoki Origuchi, Ko Chiba, Makoto Osaki, Astrid Jüngel, Steffen Gay, Atsushi Kawakami   +17 more
doaj   +1 more source

A specific aggregation-induced emission-conjugated polymer enables visual monitoring of osteogenic differentiation

Bioactive Materials, 2020
Osteogenic differentiation is the basis of bone growth and repair related to many diseases, in which evaluating the degree and ability of osteogenic transformation is quite important and highly desirable.
Zhenyu Zheng, Taotao Zhou, Rong Hu, Minjun Huang, Xiang Ao, Jun Chu, Tao Jiang, Anjun Qin, Zhongmin Zhang   +8 more
doaj   +1 more source