Results 21 to 30 of about 138,476 (311)

RUNX3 derived hsa_circ_0005752 accelerates the osteogenic differentiation of adipose-derived stem cells via the miR-496/MDM2-p53 pathway

open access: yesRegenerative Therapy, 2021
Background: Circular RNAs (circRNAs) are non-coding RNAs that play a pivotal role in bone diseases. RUNX3 was an essential transcriptional regulator during osteogenesis.
Ming Wang   +4 more
doaj   +1 more source

Bioactive sphene-based ceramic coatings on cpTi substrates for dental implants: An in vitro study [PDF]

open access: yes, 2018
Titanium implant surface modifications have been widely investigated to favor the process of osseointegration. The present work aimed to evaluate the effect of sphene (CaTiSiO5) biocoating, on titanium substrates, on the in vitro osteogenic ...
Badocco, Denis   +8 more
core   +2 more sources

BRD4 facilitates osteogenic differentiation of human bone marrow mesenchymal stem cells through WNT4/NF-κB pathway

open access: yesJournal of Orthopaedic Surgery and Research, 2023
Background Human bone marrow mesenchymal stem cells (hBMSCs) are a major source of osteoblast precursor cells and are directly involved in osteoporosis (OP) progression.
Tao Ning   +3 more
doaj   +1 more source

Expression of fibroblast growth factor receptor and its role in regulating osteoblast differentiation

open access: yesDi-san junyi daxue xuebao, 2019
Objective To investigate the changes in the expression of fibroblast growth factor receptors 1-3 (FGFR1-3) at different stages of osteogenic differentiation and clarify the role of FGFR signaling in osteogenic differentiation.
MO Qifei, YANG Peng, SU Nan, CHEN Lin
doaj   +1 more source

Effects of Extracellular Vesicles from Osteogenic Differentiated Human BMSCs on Osteogenic and Adipogenic Differentiation Capacity of Naïve Human BMSCs

open access: yesCells, 2022
Osteoporosis, or steroid-induced osteonecrosis of the hip, is accompanied by increased bone marrow adipogenesis. Such a disorder of adipogenic/osteogenic differentiation, affecting bone-marrow-derived mesenchymal stem cells (BMSCs), contributes to bone ...
Chenglong Wang   +7 more
doaj   +1 more source

Adipokines regulate mesenchymal stem cell osteogenic differentiation

open access: yesWorld Journal of Stem Cells, 2023
Mesenchymal stem cells (MSCs) can differentiate into various tissue cell types including bone, adipose, cartilage, and muscle. Among those, osteogenic differentiation of MSCs has been widely explored in many bone tissue engineering studies. Moreover, the conditions and methods of inducing osteogenic differentiation of MSCs are continuously advancing ...
Xu, Zhong-Hua   +7 more
openaire   +2 more sources

Interleukin-18 enhances vascular calcification and osteogenic differentiation of vascular smooth muscle cells through TRPM7 channel activation [PDF]

open access: yes, 2017
Objective—Vascular calcification (VC) is an important predictor of cardiovascular morbidity and mortality. Osteogenic differentiation of vascular smooth muscle cells (VSMCs) is a key mechanism of VC. Recent studies show that IL-18 (interleukin-18) favors
Chen, Jie   +7 more
core   +1 more source

Osteogenic differentiation of fibroblast-like synovial cells in rheumatoid arthritis is induced by microRNA-218 through a ROBO/Slit pathway

open access: yesArthritis Research & Therapy, 2018
Background Fibroblast-like synovial cells (FLS) have multilineage differentiation potential including osteoblasts. We aimed to investigate the role of microRNAs during the osteogenic differentiation of rheumatoid arthritis (RA)-FLS.
Naoki Iwamoto   +17 more
doaj   +1 more source

Evaluation of Current Studies to Elucidate Processes in Dental Follicle Cells Driving Osteogenic Differentiation

open access: yesBiomedicines, 2023
When research on osteogenic differentiation in dental follicle cells (DFCs) began, projects focused on bone morphogenetic protein (BMP) signaling. The BMP pathway induces the transcription factor DLX3, whichh in turn induces the BMP signaling pathway via
Christian Morsczeck   +3 more
doaj   +1 more source

Comparative study of osteogenic activity of multilayers made of synthetic and biogenic polyelectrolytes [PDF]

open access: yes, 2017
Polyelectrolyte multilayer (PEM) coatings on biomaterials are applied to tailor adhesion, growth, and function of cells on biomedical implants. Here, biogenic and synthetic polyelectrolytes (PEL) are used for layer-by-layer assembly to study the ...
Gonzalez-Garcia, Cristina   +4 more
core   +1 more source

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