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Osteogenic differentiation on DLC‐PDMS‐h surface

Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2014
AbstractThe hypothesis was that anti‐fouling diamond‐like carbon polydimethylsiloxane hybrid (DLC‐PDMS‐h) surface impairs early and late cellular adhesion and matrix–cell interactions. The effect of hybrid surface on cellular adhesion and cytoskeletal organization, important for osteogenesis of human mesenchymal stromal cells (hMSC), where therefore ...
Kaivosoja Emilia   +12 more
openaire   +5 more sources

Potential for Osteogenic and Chondrogenic Differentiation of MSC

2012
The introduction of mesenchymal stem cells (MSC) into the field of tissue engineering for bone and cartilage repair is a promising development, since these cells can be expanded ex vivo to clinically relevant numbers and, after expansion, retain their ability to differentiate into different cell lineages.
Antonina, Lavrentieva   +4 more
openaire   +2 more sources

Induction of Osteogenic Differentiation by Nanostructured Alumina Surfaces

Journal of Biomedical Nanotechnology, 2014
Permanent orthopedic implants are becoming increasingly important due to the demographic development. Their optimal osseointegration is key in obtaining good secondary stability. For anchorage dependent cells, topographic features of a surface play an essential role for cell adhesion, proliferation, differentiation and biomineralization. We studied the
Metzger, Wolfgang   +13 more
openaire   +3 more sources

Effects of different physical factors on osteogenic differentiation

Biochimie, 2023
Osteoblasts are essential for bone formation and can perceive external mechanical stimuli, which are translated into biochemical responses that ultimately alter cell phenotypes and respond to environmental stimuli, described as mechanical transduction.
Li, Peng   +7 more
openaire   +2 more sources

Regulation of osteogenic differentiation during skeletal development

Frontiers in Bioscience, 2008
Bone formation during skeletal development involves a complex coordination among multiple cell types and tissues. Bone is of crucial importance for the human body, providing skeletal support, and serving as a home for the formation of hematopoietic cells and as a reservoir for calcium and phosphate.
Zhong-Liang, Deng   +14 more
openaire   +2 more sources

Osteogenic differentiation of intact human amniotic membrane

Biomaterials, 2010
Tissue engineering strategies usually require cell isolation and combination with a suitable biomaterial. Human amniotic membrane (AM) represents a natural two-layered sheet comprising cells with proven stem cell characteristics. In our approach, we evaluated the differentiation potential of AM in toto with its sessile stem cells as alternative to ...
Andrea, Lindenmair   +9 more
openaire   +2 more sources

Berberine derivative, Q8, stimulates osteogenic differentiation

Biochemical and Biophysical Research Communications, 2018
Berberine has been implicated to be involved in maintaining bone health due to its anti-oxidative and osteogenic properties. However, low potency and low bioavailability limit the clinical development of the drug. To overcome these obstacles, we previously synthesized a compound, Q8, which is a structural homolog of berberine.
Younho Han   +2 more
openaire   +2 more sources

Effects of PRP and LyPRP on osteogenic differentiation of MSCs

Journal of Biomedical Materials Research Part A, 2019
AbstractPlatelet‐rich plasma (PRP) is rich in a variety of growth factors and plays an important role in the proliferation and differentiation of mesenchymal stem cells (MSCs). It has been reported that the preparation of freeze‐dried platelets (lyophilized platelets [LyPRP]) from platelets could be an effective strategy to preserve the bioactivity of ...
Yuxing, Xie   +7 more
openaire   +2 more sources

Osteogenic and sarcomatoid differentiation of a renal cell carcinoma

Cancer, 1985
Sarcomatoid renal cell carcinoma is an uncommon renal tumor, and osteogenic differentiation has been reported in only a few of these tumors. The authors report such a case with radiographic, light microscopic, and electron microscopic findings, which demonstrate that the sarcomatoid areas of the tumor are derived from the malignant epithelial cells ...
R A, Macke   +4 more
openaire   +2 more sources

Regulating Osteogenic Differentiation by Suppression of Exosomal MicroRNAs

Tissue Engineering Part A, 2019
We investigated the role of exosomes in osteogenesis and the use of miRNA inhibitor-transfected exosomes to control osteogenic differentiation. RNA-sequencing (RNA-seq) of exosomal miRNAs revealed that growth condition of milieu of preosteoblast exosomes harbors high levels of let-7, which plays a critical role in osteogenesis regulation.
Song-Yi, Choi   +5 more
openaire   +2 more sources

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