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Osteogenic differentiation on DLC‐PDMS‐h surface
Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2014AbstractThe hypothesis was that anti‐fouling diamond‐like carbon polydimethylsiloxane hybrid (DLC‐PDMS‐h) surface impairs early and late cellular adhesion and matrix–cell interactions. The effect of hybrid surface on cellular adhesion and cytoskeletal organization, important for osteogenesis of human mesenchymal stromal cells (hMSC), where therefore ...
Kaivosoja Emilia +12 more
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Potential for Osteogenic and Chondrogenic Differentiation of MSC
2012The introduction of mesenchymal stem cells (MSC) into the field of tissue engineering for bone and cartilage repair is a promising development, since these cells can be expanded ex vivo to clinically relevant numbers and, after expansion, retain their ability to differentiate into different cell lineages.
Antonina, Lavrentieva +4 more
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Induction of Osteogenic Differentiation by Nanostructured Alumina Surfaces
Journal of Biomedical Nanotechnology, 2014Permanent orthopedic implants are becoming increasingly important due to the demographic development. Their optimal osseointegration is key in obtaining good secondary stability. For anchorage dependent cells, topographic features of a surface play an essential role for cell adhesion, proliferation, differentiation and biomineralization. We studied the
Metzger, Wolfgang +13 more
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Effects of different physical factors on osteogenic differentiation
Biochimie, 2023Osteoblasts are essential for bone formation and can perceive external mechanical stimuli, which are translated into biochemical responses that ultimately alter cell phenotypes and respond to environmental stimuli, described as mechanical transduction.
Li, Peng +7 more
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Regulation of osteogenic differentiation during skeletal development
Frontiers in Bioscience, 2008Bone formation during skeletal development involves a complex coordination among multiple cell types and tissues. Bone is of crucial importance for the human body, providing skeletal support, and serving as a home for the formation of hematopoietic cells and as a reservoir for calcium and phosphate.
Zhong-Liang, Deng +14 more
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Osteogenic differentiation of intact human amniotic membrane
Biomaterials, 2010Tissue engineering strategies usually require cell isolation and combination with a suitable biomaterial. Human amniotic membrane (AM) represents a natural two-layered sheet comprising cells with proven stem cell characteristics. In our approach, we evaluated the differentiation potential of AM in toto with its sessile stem cells as alternative to ...
Andrea, Lindenmair +9 more
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Berberine derivative, Q8, stimulates osteogenic differentiation
Biochemical and Biophysical Research Communications, 2018Berberine has been implicated to be involved in maintaining bone health due to its anti-oxidative and osteogenic properties. However, low potency and low bioavailability limit the clinical development of the drug. To overcome these obstacles, we previously synthesized a compound, Q8, which is a structural homolog of berberine.
Younho Han +2 more
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Effects of PRP and LyPRP on osteogenic differentiation of MSCs
Journal of Biomedical Materials Research Part A, 2019AbstractPlatelet‐rich plasma (PRP) is rich in a variety of growth factors and plays an important role in the proliferation and differentiation of mesenchymal stem cells (MSCs). It has been reported that the preparation of freeze‐dried platelets (lyophilized platelets [LyPRP]) from platelets could be an effective strategy to preserve the bioactivity of ...
Yuxing, Xie +7 more
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Osteogenic and sarcomatoid differentiation of a renal cell carcinoma
Cancer, 1985Sarcomatoid renal cell carcinoma is an uncommon renal tumor, and osteogenic differentiation has been reported in only a few of these tumors. The authors report such a case with radiographic, light microscopic, and electron microscopic findings, which demonstrate that the sarcomatoid areas of the tumor are derived from the malignant epithelial cells ...
R A, Macke +4 more
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Regulating Osteogenic Differentiation by Suppression of Exosomal MicroRNAs
Tissue Engineering Part A, 2019We investigated the role of exosomes in osteogenesis and the use of miRNA inhibitor-transfected exosomes to control osteogenic differentiation. RNA-sequencing (RNA-seq) of exosomal miRNAs revealed that growth condition of milieu of preosteoblast exosomes harbors high levels of let-7, which plays a critical role in osteogenesis regulation.
Song-Yi, Choi +5 more
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