Results 71 to 80 of about 7,514 (117)

Development of an early estimation method for predicting later osteogenic differentiation activity of rat mesenchymal stromal cells from their attachment areas

open access: yesScience and Technology of Advanced Materials, 2012
Cell morphology has received considerable attention in recent years owing to its possible relationship with cell functions, including proliferation, differentiation, and migration. Recent evidence suggests that extracellular environments can also mediate
Kan Cheng, Motohiro Hirose, Xiupeng Wang, Yu Sogo, Atsushi Yamazaki and Atsuo Ito
doaj   +1 more source

Y‐Box‐Binding Protein 1 Facilitates the Proliferation and Osteogenic Differentiation of Periodontal Ligament Stem Cells Through the Transcriptional Activation of FGF2‐Mediated Akt/GSK3β/β‐Catenin Signaling

open access: yesKaohsiung Journal of Medical Sciences
Periodontal ligament stem cells (PDLSCs) are derived from periodontal tissue and can differentiate into osteoblasts, which are ideal materials for alveolar bone repair and periodontal tissue regeneration. In this study, we aimed to explore the effects of
Yun‐Hao Xi   +5 more
doaj   +1 more source
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In vitro induction of osteogenic differentiation from non-osteogenic mesenchymal cells

Biomaterials, 1997
The process of ectopic bone formation suggests that extraskeletal cells are capable of osteogenesis. Alkaline phosphatase (ALP) activity is considered to be an early marker of osteogenic differentiation. This study determined whether cells from the rabbit dermis, striated muscle and extramedullary adipose tissue could undergo osteogenic differentiation
J P Ouhayoun
exaly   +3 more sources

Osteogenic Sarcoma with Epithelial Differentiation

Ultrastructural Pathology, 1992
This case report details an osteogenic sarcoma arising in a vertebra in which cytokeratin intermediate filaments were detected immunohistochemically with three different antibodies. This feature was present not only in the primary neoplasm but also in two local recurrences and a metastasis to the iliac bone. What is unique about this primary bone tumor,
I, Dardick, J E, Schatz, T J, Colgan
openaire   +2 more sources

Laminins in osteogenic differentiation and pluripotency maintenance

Differentiation, 2020
Extracellular matrix (ECM) plays an integral role in different developmental stages and in multiple systems. However, due to ECM being composed of various extracellular components (growth factors, cytokines, and hormones), its innate complexity and the lack of any efficient purification techniques limit further research into the detailed mechanisms of ...
Chaozhen Chen, Zhiwei Jiang, Guoli Yang
openaire   +2 more sources

Role of MT1-MMP in the osteogenic differentiation

Bone, 2009
Metalloproteinase MT1-MMP is induced and Pro-MMP-2 up modulated early in rat preosteoblasts (ROB) set to differentiate. We here show that the induction of MMPs, accompanied by activation of Pro-MMP-2, occurs by 6 h of adhesion on endogenous extracellular matrix (ECM), Fibronectin (FN) and Collagen type I (CI).
Manduca P   +9 more
openaire   +4 more sources

Roles of circular RNAs in osteogenic/osteoclastogenic differentiation

BioFactors, 2023
AbstractThe process of bone remodeling occurs and is regulated through interactions between osteoclasts, which resorb bone, and osteoblasts, which generate bone tissue. When the homeostatic balance between these two cell types is dysregulated, this can contribute to abnormal bone remodeling resulting in a loss of bone mass as is observed in ...
Tao Wang   +3 more
openaire   +2 more sources

Epigenetic modifications in osteogenic differentiation and transformation

Journal of Cellular Biochemistry, 2006
AbstractAlmost all tumors are characterized by both architectural and cellular abnormalities in differentiation. Osteoblast development is relatively well understood, making osteosarcoma a good model for understanding how tumorigenesis perturbs normal differentiation.
David, Thomas, Maya, Kansara
openaire   +2 more sources

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