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Cell morphology has received considerable attention in recent years owing to its possible relationship with cell functions, including proliferation, differentiation, and migration. Recent evidence suggests that extracellular environments can also mediate
Kan Cheng, Motohiro Hirose, Xiupeng Wang, Yu Sogo, Atsushi Yamazaki and Atsuo Ito
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Periodontal ligament stem cells (PDLSCs) are derived from periodontal tissue and can differentiate into osteoblasts, which are ideal materials for alveolar bone repair and periodontal tissue regeneration. In this study, we aimed to explore the effects of
Yun‐Hao Xi +5 more
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[On the differential diagnosis of osteogenic sarcoma].
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MicroRNA regulation of osteogenic differentiation.
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In vitro induction of osteogenic differentiation from non-osteogenic mesenchymal cells
Biomaterials, 1997The process of ectopic bone formation suggests that extraskeletal cells are capable of osteogenesis. Alkaline phosphatase (ALP) activity is considered to be an early marker of osteogenic differentiation. This study determined whether cells from the rabbit dermis, striated muscle and extramedullary adipose tissue could undergo osteogenic differentiation
J P Ouhayoun
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Osteogenic Sarcoma with Epithelial Differentiation
Ultrastructural Pathology, 1992This case report details an osteogenic sarcoma arising in a vertebra in which cytokeratin intermediate filaments were detected immunohistochemically with three different antibodies. This feature was present not only in the primary neoplasm but also in two local recurrences and a metastasis to the iliac bone. What is unique about this primary bone tumor,
I, Dardick, J E, Schatz, T J, Colgan
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Laminins in osteogenic differentiation and pluripotency maintenance
Differentiation, 2020Extracellular matrix (ECM) plays an integral role in different developmental stages and in multiple systems. However, due to ECM being composed of various extracellular components (growth factors, cytokines, and hormones), its innate complexity and the lack of any efficient purification techniques limit further research into the detailed mechanisms of ...
Chaozhen Chen, Zhiwei Jiang, Guoli Yang
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Role of MT1-MMP in the osteogenic differentiation
Bone, 2009Metalloproteinase MT1-MMP is induced and Pro-MMP-2 up modulated early in rat preosteoblasts (ROB) set to differentiate. We here show that the induction of MMPs, accompanied by activation of Pro-MMP-2, occurs by 6 h of adhesion on endogenous extracellular matrix (ECM), Fibronectin (FN) and Collagen type I (CI).
Manduca P +9 more
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Roles of circular RNAs in osteogenic/osteoclastogenic differentiation
BioFactors, 2023AbstractThe process of bone remodeling occurs and is regulated through interactions between osteoclasts, which resorb bone, and osteoblasts, which generate bone tissue. When the homeostatic balance between these two cell types is dysregulated, this can contribute to abnormal bone remodeling resulting in a loss of bone mass as is observed in ...
Tao Wang +3 more
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Epigenetic modifications in osteogenic differentiation and transformation
Journal of Cellular Biochemistry, 2006AbstractAlmost all tumors are characterized by both architectural and cellular abnormalities in differentiation. Osteoblast development is relatively well understood, making osteosarcoma a good model for understanding how tumorigenesis perturbs normal differentiation.
David, Thomas, Maya, Kansara
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