Multicenter Performance Evaluation of MALDI-TOF MS for Rapid Detection of Carbapenemase Activity in Enterobacterales: The Future of Networking Data Analysis With Online Software [PDF]
In this study, we evaluate the performance of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) for rapid detection of carbapenemase activity in Enterobacterales in clinical microbiology laboratories during a ...
Anantharajah, Ahalieyah +7 more
core +1 more source
Diverse reactivity of maleimides in polymer science and beyond
This mini‐review provides a thorough overview of maleimide chemistry, highlighting its diverse reactivity in polymer and materials science applications. Abstract Maleimides are remarkably versatile functional groups, capable of participating in homo‐ and copolymerizations, Diels–Alder and (photo)cycloadditions, Michael additions, and other reactions ...
Bruce E Kirkpatrick +2 more
wiley +1 more source
Genomic surveillance for hypervirulence and multi-drug resistance in invasive Klebsiella pneumoniae from South and Southeast Asia. [PDF]
BACKGROUND: Klebsiella pneumoniae is a leading cause of bloodstream infection (BSI). Strains producing extended-spectrum beta-lactamases (ESBLs) or carbapenemases are considered global priority pathogens for which new treatment and prevention strategies ...
Baker, S +19 more
core +8 more sources
Emergence of Dual and Multicarbapenemase Coproducing organisms in the United States [PDF]
Carbapenemase-producing organisms commonly carry a single carbapenemase gene conferring resistant to carbapenems and other β-lactam antibiotics.
Darkoh, Charles +2 more
core +2 more sources
A total of 132 Multidrug‐resistant Klebsiella pneumoniae was detected across the beef value chain in Bangladesh, including slaughterhouses, wet markets, and ready‐to‐eat beef outlets. Upon cultural traits, PCR, 16S rRNA sequencing, antibiogram analysis, and ARG detection revealed carbapenem resistance genes (blaIMP and blaBIC), highlighting foodborne ...
Md Sodor Uddin +11 more
wiley +1 more source
Rapidly spreading Enterobacterales with OXA-48-like carbapenemases
Enterobacterales (mostly Klebsiella pneumoniae, Escherichia coli) with OXA-48-like carbapenemases (e.g., OXA-48, -181, -232, -244) are undermining the global efficiency of carbapenem therapy. In the Middle East, North Africa, and some European countries,
Gisele Peirano, Johann D. D. Pitout
doaj +1 more source
Heterogeneous hydrolytic features for OXA-48-like β-lactamases [PDF]
Objectives Carbapenem-hydrolysing class D β-lactamases of the OXA-48 type are increasingly reported from Enterobacteriaceae. β-Lactamase OXA-48 hydrolyses penicillins very efficiently, but carbapenems only weakly and spares broad-spectrum cephalosporins.
Nordmann, Patrice +2 more
core
Multicenter performance evaluation of MALDI-TOF MS for rapid detection of carbapenemase activity ineEnterobacterales: the future of networking data analysis with online software [PDF]
[Abstract] In this study, we evaluate the performance of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) for rapid detection of carbapenemase activity in Enterobacterales in clinical microbiology laboratories ...
Gato, Eva +24 more
core +2 more sources
Do's and Don'ts When Visiting Circularly Polarized Luminescence
This perspective presents our insights into the principles, challenges, and opportunities of circularly polarized luminescence (CPL). Highlighting key concepts such as the dissymmetry factor (glum) and molecular design strategies, we discuss advances in CPL efficiency, emerging NIR emitters, solid‐state applications, and the growing role of theory and ...
Rafael G. Uceda +9 more
wiley +1 more source
Molecular characterization of Danish ESBL/AmpC-producing Klebsiella pneumoniae from bloodstream infections, 2018 [PDF]
Objectives: The aim of the study was to molecularly characterize third-generation cephalosporin-resistant Klebsiella pneumoniae isolated from bloodstream infections in Denmark in 2018 using whole-genome sequencing (WGS) data, and to compare these ...
Andersen, Leif Percival +16 more
core +2 more sources

