Results 101 to 110 of about 40,843 (302)
Flexoelectricity in an oxadiazole bent-core nematic liquid crystal [PDF]
, 2014 We have determined experimentally the magnitude of the difference in the splay and bend flexoelectric coefficients, |e1 - e3|, of an oxadiazole bent-core liquid crystal by measuring the critical voltage for the formation of flexodomains together with ...
A. Ferrarini +10 more
core +2 more sources
International Journal of Molecular SciencesHeterocycles are fundamental moieties for the construction of new compounds with perspective applications ranging from drugs to materials [...]
openaire +3 more sources
Acta Crystallographica Section D, Volume 81, Issue 8, Page 451-464, August 2025.Very high‐resolution fatty acid‐binding protein structures identified a substantial number of ligands that differ strongly from their expected structure. If different ligand chemistry is a potentially overlooked problem in other, lower resolution, crystal structures of protein–ligand complexes, it has repercussions for any study using such structures ...
Andreas Ehler +4 more
wiley +1 more source
A Fragment-Based Approach for the Development of G-Quadruplex Ligands: Role of the Amidoxime Moiety [PDF]
, 2018 G-quadruplex (G4) nucleic acid structures have been reported to be involved in several human pathologies, including cancer, neurodegenerative disorders and infectious diseases; however, G4 targeting compounds still need implementation in terms of drug ...
Butovskaya, Elena +7 more
core +2 more sources
ChemMedChemAbstractTuberculosis remains a leading global health threat, exacerbated by the emergence of multi‐drug‐resistant strains. The search for novel therapeutic agents is critical in addressing this challenge. This review systematically summarizes the potential of oxadiazole derivatives as promising candidates in antimycobacterial drug discovery.
openaire +2 more sources
eAmidation: An Electrochemical Amidation of Aldehydes via the Oxidation of N‐Aryl Hydrazones
Advanced Synthesis &Catalysis, Volume 367, Issue 14, July 29, 2025.The indirect electrochemical oxidation of N‐aryl hydrazones offers an efficient approach to access amides from aldehydes and amines. The AZADO‐mediated reaction enables the selective synthesis of a broad range of valuable amides using readily available aldehydes.
Luke Chen +2 more
wiley +1 more source
The dissociation of the Hsp60/pro-Caspase-3 complex by bis(pyridyl)oxadiazole copper complex (CubipyOXA) leads to cell death in NCI-H292 cancer cells [PDF]
, 2017 Cell survival and proliferation are central to carcinogenesis, involving various mechanisms among which those that impede apoptosis are important. In this, the role of the molecular chaperone Hsp60 is unclear since it has been reported that it can be ...
Barone, G. +14 more
core +1 more source
Anti-Cancer Activity of Derivatives of 1,3,4-Oxadiazole
Molecules, 2018 Compounds containing 1,3,4-oxadiazole ring in their structure are characterised by multidirectional biological activity. Their anti-proliferative effects associated with various mechanisms, such as inhibition of growth factors, enzymes, kinases and ...
T. Glomb +2 more
semanticscholar +1 more source
Design, synthesis, and biological activity of novel 1,2,4-oxadiazole derivatives
BMC Chemistry, 2020 Background Plant diseases seriously threaten food security, it is urgent to discover efficient and low-risk chemical pesticides. 1,2,4-Oxadiazole derivatives exhibit broad spectrum of agricultural biological activities.
Lingzhi Zhu +6 more
semanticscholar +1 more source
Molecules, 2006 (7-Hydroxy-2-oxo-2H-chromen-4-yl)-acetic acid hydrazide (2) was prepared from (7-hydroxy-2-oxo-2H-chromen-4-yl)-acetic acid ethyl ester (1) and 100% hydrazine hydrate.
Elizabeth Has-Schon +3 more
doaj +1 more source