Results 21 to 30 of about 40,843 (302)
Synthesis and characterization of 5-aryl-1,3,4-oxadiazole-2(3h)thione derivatives
Journal of Applied Pharmaceutical Research, 2020 1,3,4-oxadiazoles represent a class of heterocyclic five membered compounds it contain two nitrogen and one oxygen of great importance in Pharmaceutical chemistry. This nucleus show four isomeric forms 1,2,4-oxadiazole,1,3,4-oxadiazole, 1,2,5-oxadiazole,
Shailesh Pathak +3 more
doaj +1 more source
Frontiers in Chemistry, 2022 Bacterial resistance to antibiotics is an ever-growing problem in heathcare. We have previously identified a set of osmium(II), ruthenium(II), iridium(III) and rhodium(III) half-sandwich type complexes with bidentate monosaccharide ligands possessing ...
Bence Balázs +11 more
doaj +1 more source
International Journal of Molecular Sciences, 2022 Furan-oxadiazole structural hybrids belong to the most promising and biologically active classes of oxygen and nitrogen containing five member heterocycles which have expanded therapeutic scope and potential in the fields of pharmacology, medicinal ...
Ali Irfan +4 more
semanticscholar +1 more source
Molecules, 2022 Dipeptidyl peptidase-IV (DPP-IV) inhibitors, often known as gliptins, have been used to treat type 2 diabetes mellitus (T2DM). They may be combined with other medications as an additional treatment or used alone as a monotherapy.
Badrud Duza Mohammad +8 more
doaj +1 more source
Gas separation properties of a thermally stable and chemically resistant polytriazole membrane [PDF]
, 1989 The polymer poly (1,3-phenyl-1,4-phenyl)-4-phenyl-1,3,4-triazole has been investigated for its gas separation properties. This thermally stable and chemically resistant polymer can be processed into membranes by the phase-inversion technique because of ...
Gebben, B. +2 more
core +7 more sources
Biomedicines, 2023 Nuclear factor kappa beta (NF-κB) is a transcriptional factor that plays a crucial role in regulating cancer cell proliferation. Therefore, the inhibition of NF-κB activity by small molecules may be beneficial in cancer therapy.
Basappa Basappa +9 more
doaj +1 more source
Design and Activity of Novel Oxadiazole Based Compounds That Target Poly(ADP-ribose) Polymerase
Molecules, 2022 Novel PARP inhibitors with selective mode-of-action have been approved for clinical use. Herein, oxadiazole based ligands that are predicted to target PARP-1 have been synthesized and screened for the loss of cell viability in mammary carcinoma cells ...
Divakar Vishwanath +7 more
doaj +1 more source
Green Chemistry Synthesis of Five-Membered Heterocylic Derivatives (1, 3, 4-oxadizoles) by Using Grinding Technique [PDF]
Kirkuk Journal of Science, 2018 In this research we prepared about 28 derivatives of five-membered heterocyclic compounds (1,3,4-oxadizoles) in two lines , in the first line we used phenylhydrazide and in the second line we used 4-hydroxy phenylhydrazide as starting material for ...
Nihad Taha, Eehab Rasheed
doaj +1 more source
Investigation on Quantitative Structure-Activity Relationships of 1,3,4 Oxadiazole Derivatives as Potential Telomerase Inhibitors [PDF]
, 2018 The published manuscript is available at EurekaSelect via http://www.eurekaselect.com/164022/article, DOI : 10.2174/1570163815666180724113208. © 2018 Bentham ScienceA series of 1,3,4-oxadiazole derivatives with significant broad-spectrum anticancer ...
Almerico, Anna Maria +2 more
core +2 more sources
Synthesis and Anticancer Evaluation of New 1,3,4-Oxadiazole Derivatives
Pharmaceuticals, 2021 In order to develop novel chemotherapeutic agents with potent anticancer activities, a series of new 2,5-diaryl/heteroaryl-1,3,4-oxadiazoles were designed and synthesized.
C. Stecoza +6 more
semanticscholar +1 more source