Results 41 to 50 of about 41,732 (296)

BIOLOGICALLY ACTIVE OXADIAZOLE

Journal of Drug Delivery and Therapeutics, 2015
As we know that, Oxadiazole is a heterocyclic compound containing an oxygen atom and two nitrogen atoms in a five-membered ring and is derived from furan by substitution of two methylene groups (=CH) with two pyridine type nitrogen (-N=) [1,2]. There are three known isomers that is 1,2,4-oxadiazole, 1,2,3-oxadiazole and 1,2,5-oxadiazole (Figure 1.0 ...
Chhama Shukla, Sanchit Srivastav
openaire   +2 more sources

(1-(4-(5-Phenyl-1,3,4-oxadiazol-2-yl)phenyl)-1H-1,2,3-triazol-4-yl)-methylenyls α,ω-Bisfunctionalized 3- and 4-PEG: Synthesis and Photophysical Studies

Molecules, 2023
Two new azaheterocycle-based bolas, such as (1-(4-(5-phenyl-1,3,4-oxadiazol-2-yl)phenyl)-1H-1,2,3-triazol-4-yl)-methylenyls α,ω-bisfunctionalized PEGs, were prepared via Cu-catalyzed click reaction between 2-(4-azidophenyl)-5-(aryl)-oxadiazole-1,3,4 and ...
Mohammed S. Mohammed, Igor S. Kovalev, Natalya V. Slovesnova, Leila K. Sadieva, Vadim A. Platonov, Grigory A. Kim, Rammohan Aluru, Alexander S. Novikov, Olga S. Taniya, Valery N. Charushin   +9 more
doaj   +1 more source

Thermal behavior of polytriazole films: a thermal analysis study [PDF]

, 1989
The thermal behavior of poly(1,3-phenyl-1,4-phenyl)-4-phenyl-1,2,4-triazole has been investigated using different scanning calorimetry (DSC) and thermogravimetry (TG).
Gebben, B., Mulder, M.H.V., Smolders, C.A.   +2 more
core   +2 more sources

Strategies against nonsense: oxadiazoles as translational readthrough-inducing drugs (TRIDs) [PDF]

, 2019
This review focuses on the use of oxadiazoles as translational readthrough-inducing drugs (TRIDs) to rescue the functional full-length protein expression in mendelian genetic diseases caused by nonsense mutations.
Campofelice A., Di Leonardo A., Lentini L., Melfi R., Pace A., Pibiri I., Tutone M.   +6 more
core   +1 more source

1,3,4-Oxadiazole N-Mannich Bases: Synthesis, Antimicrobial, and Anti-Proliferative Activities

Molecules, 2021
The reaction of 5-(3,4-dimethoxyphenyl)-1,3,4-oxadiazole-2(3H)-thione 3 with formaldehyde solution and primary aromatic amines or 1-substituted piperazines, in ethanol at room temperature yielded the corresponding N-Mannich bases 3-arylaminomethyl-5-(3,4-
L. Al-Wahaibi, A. A. Mohamed, Samar S. Tawfik, H. M. Hassan, A. El-Emam   +4 more
semanticscholar   +1 more source

A study of cell membranes in nasal epithelial cells from patients with chronic rhinosinusitis with nasal polyps by means of a fluorescent probe [PDF]

, 2009
Aim. To assess the state of membranes in nasal epithelial cells obtained from the patients with chronic rhinosinusitis with nasal polyps (CRSwNP) with the help of the fluorescent probe 2-(2ʹ-ОН-phenyl)-5-phenyl-1,3-oxazole. Methods. The state of membrane
Onishchenko, A. I., Tkachenko, A. S., Nakonechna, O. A., Korniyenko, Y. M., Ryshchenko, I. M., Tsygankov, A. V., Posokhov, Y. O.   +6 more
core   +2 more sources

Synthesis of N, N΄3, 4-Dialkylamino-1, 2, 5-Oxadiazoles [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2003
N, N΄-3, 4-di(methylamino)-1, 2, 5-oxadiazole (1f) was prepared by dehydration of N, N΄-3, 4-di(methylamino)glyoxime (2f) in aqueous potassium hydroxid at 170-180 ˚C. Under similar conditions N, N΄-3, 4-di(benzylamino)-1, 2, 5-oxadiazole (1c) and N, N΄-3,
Ali Kakanejadifardi, Farshad Delfani, Bijan Ranjbar   +2 more
doaj  

2-(5-Methyl-1-phenyl-1H-1,2,3-triazol-4-yl)-5-phenyl-1,3,4-oxadiazole

IUCrData, 2018
The asymmetric unit of the title compound, C17H13N5O, comprises four independent molecules (A–D). The respective interplanar angles between the phenyl/oxadiazole/methyltriazole/phenyl rings for the four independent molecules are A 8.8 (2), 13.0 (2), 22.5 
Gamal A. El-Hiti, Bakr F. Abdel-Wahab, Mohamed S. Mostafa, Rizk E. Khidre, Amany S. Hegazy, Benson M. Kariuki   +5 more
doaj   +1 more source

Synthesis, biological evaluation and docking studies of 1,2,4-oxadiazole linked 5-fluorouracil derivatives as anticancer agents

BMC Chemistry, 2021
Background 1,2,4-oxadiazole derivatives exhibited significant anti-cancer activity when they were evaluated, against human cancer cell lines. They also showed anti-inflammatory, analgesic, diabetic, immunosuppressive, α,β 3 -receptor antagonist ...
Ravi Kumar Bommera, S. Kethireddy, R. R. Govindapur, L. Eppakayala   +3 more
semanticscholar   +1 more source

3-[5-(Pyridin-4-yl)-1,3,4-oxadiazol-2-yl]-4H-chromen-4-one

IUCrData, 2016
In the title molecule, C16H9N3O3, the plane of oxadiazole ring is almost coplanar with attached pyridine ring and chromenyl ring system, forming dihedral angles of 2.37 (3) and 6.71 (2)°, respectively.
Dongsoo Koh
doaj   +1 more source