Results 71 to 80 of about 41,732 (296)

A Fragment-Based Approach for the Development of G-Quadruplex Ligands: Role of the Amidoxime Moiety [PDF]

, 2018
G-quadruplex (G4) nucleic acid structures have been reported to be involved in several human pathologies, including cancer, neurodegenerative disorders and infectious diseases; however, G4 targeting compounds still need implementation in terms of drug ...
Butovskaya, Elena, Doria, Filippo, Freccero, Mauro, Lena, Alberto, Nadai, Matteo, Pirota, Valentina, Richter, Sara N, Tassinari, Martina   +7 more
core   +2 more sources

Harnessing benzamides as plant stress inhibitors, growth promoters and in management of crop resilience—A review

Plant Biology, EarlyView.
Benzamides boost crop resilience by inhibiting poly(ADP‐ribose) polymerase (PARP) to enhance stress tolerance and, through their antimicrobial, herbicidal, and insecticidal derivatives, they offer broad protection for sustainable crop improvement. Abstract Benzamides have emerged as potent stress inhibitors and growth promoters in plant biotechnology ...
M. J. Koetle, T. E. Motaung, S. O. Amoo
wiley   +1 more source

Study on the synthesis of novel 5-substituted 2-[2-(pyridyl)ethenyl]-1,3,4-oxadiazoles and their acid–base interactions [PDF]

, 2014
: A series of novel 5-substituted 2-[2-(pyridyl)ethenyl]-1,3,4-oxadiazoles were efficiently synthesized by cyclocondensation of the appropriate 3-(pyridyl)acrylohydrazides with triethyl orthoesters in the presence of glacial acetic acid.
Agnieszka Kudelko, Karolina Jasiak, Krzysztof Ejsmont   +2 more
core   +1 more source

Groundbreaking Anticancer Activity of Highly Diversified Oxadiazole Scaffolds

International Journal of Molecular Sciences, 2020
Nowadays, an increasing number of heterocyclic-based drugs found application in medicinal chemistry and, in particular, as anticancer agents. In this context, oxadiazoles—five-membered aromatic rings—emerged for their interesting biological properties ...
A. Benassi, F. Doria, Valentina Pirota
semanticscholar   +1 more source

Investigation of the printability of ethyl 2‐[4‐(1,3,4‐oxadiazol‐2(3H)‐thion‐5‐yl)phenylhydrazono]‐3‐oxobutyrate on coated and uncoated papers

Coloration Technology, Volume 142, Issue 1, Page 67-74, February 2026.
Abstract There is a growing demand in the printing industry for pigment‐based inks with excellent lightfastness and rub resistance qualities. In this work, a novel ink with the formulation ethyl 2‐[4‐(1,3,4‐oxadiazole‐2(3H)‐thione‐5‐yl)phenylhydrazono]‐3‐oxobutyrate (OXKT) was prepared as a pigment and its printability was investigated for use in ...
Ahmet Akgül, Ş. Güniz Küçükgüzel, Mehmet Oktav, Sevim Rollas   +3 more
wiley   +1 more source

Synthesis and in vitro antibacterial activity of new oxoethylthio-1,3,4-oxadiazole derivatives

Journal of Saudi Chemical Society, 2014
In the present investigation, a series of 2(4-pyridyl)-5[(aryl/heteroarylamino)-1-oxoethyl]thio-1,3,4-oxadiazole were synthesized using isonicotinohydrazide and substituted aryl/heteroaryl amines using pyridine as solvent.
Jignesh P. Raval, Tarunkumar N. Akhaja, Dhaval M. Jaspara, Kruti N. Myangar, Nilesh H. Patel   +4 more
doaj   +1 more source

Synthesis of Fluorinated Bent-Core Mesogens (BCMs) Containing the 1,2,4-Oxadiazole Ring [PDF]

, 2015
New fluorinated bent-core mesogens containing the 1,2,4-oxadiazole or 1,2,4-triazole nucleus have been synthesized taking advantage of the ANRORC (Addition of Nucleophile, Ring-Opening, Ring-Closure) reactivity of 5-perfluoroalkyl-1,2,4-oxadiazoles ...
Amaranatha, Buscemi, Buscemi, Buscemi, Buscemi, Buscemi, Fortuna, Francescangeli, Gallardo, Gallardo, Gallardo, Gortz, Hird, Keith, Link, Lo Celso, Mandracchia, Meunier, Pace, Palumbo, Palumbo, Palumbo, Palumbo, Palumbo, Palumbo Piccionello, Parra, Parra, Pelzl, Pelzl, Pibiri, Prasad, Reddy, Ros, Shanker, Shanker, Speetjens, Terenzi, Terenzi, Torgova, Traskovskis, Tschierske, Tschierske, Van der Plas, Zafiropoulos   +43 more
core   +1 more source

Synthesis and Biological Evaluation of β-Phenylalanine Derivatives Containing Sulphonamide and Azole Moieties as Antiproliferative Candidates in Lung Cancer Models

Molecules
In this study, a series of novel β-phenylalanine derivatives were synthesised and evaluated for their anticancer activity. The 3-(4-methylbenzene-1-sulfonamido)-3-phenylpropanoic acid (2) was prepared using β-phenylalanine as a core scaffold. The β-amino
Vytautas Mickevičius, Kazimieras Anusevičius, Birutė Sapijanskaitė-Banevič, Ilona Jonuškienė, Linas Kapočius, Birutė Grybaitė, Ramunė Grigalevičiūtė, Povilas Kavaliauskas   +7 more
doaj   +1 more source

Chromaticity Control in Light‐Emitting Electrochemical Cells via Thermally Activated Emission in Assemblies of a BN‐Doped Pyrenyl Hydrocarbon

Advanced Functional Materials, Volume 36, Issue 5, 15 January 2026.
The successful color control in light‐emitting electrochemical cells based on highly emissive green‐emitting BN‐doped polyaromatic hydrocarbon with thermally activated NIR emitting assemblies. Abstract This work outlines the synthesis and photo‐/electro‐luminescent behavior of a new C‐shaped BN‐doped benzenoid hydrocarbon using N‐directed borylation in
Luca M. Cavinato, Marco Franceschini, Laura Caputo, Jean‐Christophe Charlier, Marc de Wergifosse, Davide Bonifazi, Rubén D. Costa   +6 more
wiley   +1 more source

The first metal complexes of 3,3'-bi-1,2,4-oxadiazole: A curiously ignored ligand [PDF]

, 2006
The crystal structure of 3,3'-bi-1,2,4-oxadiazole (1) reveals a planar centrosymmetric structure for this molecule in the solid state. It forms a mononuclear complex (3) with palladium(II) chloride, which is shown by X-ray crystallography to contain the ...
Richardson, C., Steel, P.J.
core   +2 more sources