Results 11 to 20 of about 30,928 (305)
A survey of liquid crystalline oxadiazoles [PDF]
ChemInform, Published Online: 21 Jul 2008, 2008 We propose a survey of those oxadiazole compounds, which are mesogenic. We will see that they can have bend-shaped molecules, a biaxial nematic phase, or other interesting peculiarities in the nematic and smectic phase. With large electric dipoles and luminescent properties, these materials are also very appealing for technological applications.
Sparavigna, Amelia
arxiv +7 more sources
Strategies against Nonsense: Oxadiazoles as Translational Readthrough-Inducing Drugs (TRIDs) [PDF]
International Journal of Molecular Sciences, 2019 This review focuses on the use of oxadiazoles as translational readthrough-inducing drugs (TRIDs) to rescue the functional full-length protein expression in mendelian genetic diseases caused by nonsense mutations.
Ambra Campofelice +6 more
semanticscholar +3 more sources
Bioactive Oxadiazoles 3.0. [PDF]
Int J Mol SciHeterocycles are fundamental moieties for the construction of new compounds with perspective applications ranging from drugs to materials [...]
Palumbo Piccionello A.
europepmc +4 more sources
Bioscience Journal, 2022 In recent years, investigations in the field of oxadiazoles have been intensified due to their numerous therapeutic uses. Oxadiazoles are a class of compounds that exhibit several biological applications, citing antimicrobial, anti-inflammatory, anti ...
Josefa Aqueline da Cunha Lima +6 more
doaj +1 more source
Synthesis and Biological Activity of 1,3,4-Oxadiazoles Used in Medicine and Agriculture
Applied Sciences, 2022 Biologically active compounds play a key role in the fight against diseases affecting both human and animal living organisms, as well as plants. Finding out about new molecules with a potential biological effect, not yet described in the literature, is ...
Marcin Luczynski, A. Kudelko
semanticscholar +1 more source
A review on synthetic account of 1,2,4-oxadiazoles as anti-infective agents
Molecular diversity, 2022 Most of the currently marketed drugs consist of heterocyclic scaffolds containing nitrogen and or oxygen as heteroatoms in their structures. Several research groups have synthesized diversely substituted 1,2,4-oxadiazoles as anti-infective agents having ...
Tejas M. Dhameliya +3 more
semanticscholar +1 more source
Molecules, 2022 Dipeptidyl peptidase-IV (DPP-IV) inhibitors, often known as gliptins, have been used to treat type 2 diabetes mellitus (T2DM). They may be combined with other medications as an additional treatment or used alone as a monotherapy.
Badrud Duza Mohammad +8 more
semanticscholar +1 more source
Synthesis of 2,5-Dialkyl-1,3,4-oxadiazoles Bearing Carboxymethylamino Groups
Molecules, 2022 A series of new symmetrical 2,5-dialkyl-1,3,4-oxadiazoles containing substituted alkyl groups at the terminal positions with substituents, such as bromine, isopropyloxycarbonylmethylamino, and carboxymethylamino, were successfully synthesized.
Marcin Łuczyński +2 more
doaj +1 more source
The oxadiazole antibacterials [PDF]
Current Opinion in Microbiology, 2016 The oxadiazoles are a class of antibacterials discovered by in silico docking and scoring of compounds against the X-ray structure of a penicillin-binding protein. These antibacterials exhibit activity against Gram-positive bacteria, including against methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE).
Shahriar Mobashery +2 more
openaire +3 more sources
Synthesis and characterization of new phthalimides and succinimides substituted with 1,3,4-oxadiazole ring [PDF]
مجلة جامعة الانبار للعلوم الصرفة, 2012 A series of new phthalimides and succinimides connected to 1,3,4-oxadiazole moiety were synthesized via multistep synthesis. The first step involved synthesis of six 5- substituted 2- amino-1,3,4-oxadiazoles by oxidative cyclization of substituted ...
Ahlam Marouf Al-Azzawi +1 more
doaj +1 more source