Results 41 to 50 of about 11,559 (254)
Frame‐Shifted Synthesis of Oligoheterocycles as a Platform for Molecular Design
Angewandte Chemie, Volume 138, Issue 2, 9 January 2026.Modern chemistry seeks to turn the simple raw materials into complex molecules that matter in health, agriculture, and technology. Among these, oligoheterocycles stand out for their versatility, yet they are most often built by cross‐coupling reactions that often rely on expensive metal catalysts.
Kane A. C. Bastick +6 more
wiley +2 more sources
Beilstein Journal of Organic Chemistry, 2015 The reaction of α-azidochalcones with carboxylic acids has been investigated resulting in the formation of α-amido-1,3-diketones under microwave irradiation via in situ formation of 2H-azirine intermediates.
Kandasamy Rajaguru +4 more
doaj +1 more source
Oxazole and thiazole analogs of sulindac for cancer prevention [PDF]
, 2018 Aim: Experimental and epidemiological studies and clinical trials suggest that nonsteroidal anti-inflammatory drugs possess antitumor potential. Sulindac, a widely used nonsteroidal anti-inflammatory drug, can prevent adenomatous colorectal polyps and ...
Connelly, Michele C. +4 more
core +2 more sources
Beilstein Journal of Organic Chemistry, 2019 The LANCA three-component reaction of lithiated alkoxyallenes LA, nitriles N and carboxylic acids CA leads to β-ketoenamides KE in good to excellent yields.
Tilman Lechel +4 more
doaj +1 more source
Recent Advances on O-Ethoxycarbonyl and O-Acyl Protected Cyanohydrins
Molecules, 2021 Ethoxycarbonyl cyanohydrins and O-acyl cyanohydrins are examples of O-protected cyanohydrins in which the protecting group presents an electrophilic center, contributing to additional reaction pathways.
Héctor Manuel Torres Domínguez +2 more
doaj +1 more source
Molecules, 2020 Mesoionics are neutral compounds that cannot be represented by a fully covalent or purely ionic structure. Among the possible mesomeric structures of these compounds are the diradical electronic configurations.
Antonio João da Silva Filho +2 more
doaj +1 more source
Applied Sciences, 2022 In this paper, we report on the antimicrobial activity assessment of 49 compounds previously synthesized as derivatives of alanine or phenylalanine that incorporate a 4-(4-X-phenylsulfonyl)phenyl fragment (X = H, Cl, or Br), namely 21 acyclic compounds ...
Theodora-Venera Apostol +8 more
doaj +1 more source
Synergistic Anti-Candida Activity of Bengazole A in the Presence of Bengamide A †. [PDF]
, 2019 Bengazoles A⁻G from the marine sponge Jaspis sp. exhibit potent in vitro antifungal activity against Candida spp. and other pathogenic fungi. The mechanism of action (MOA) of bengazole A was explored in Candida albicans under both liquid culture and ...
Cheng, Tina +3 more
core
The rapid synthesis of oxazolines and their heterogeneous oxidation to oxazoles under flow conditions. [PDF]
, 2014 A rapid flow synthesis of oxazolines and their oxidation to the corresponding oxazoles is reported. The oxazolines are prepared at room temperature in a stereospecific manner, with inversion of stereochemistry, from β-hydroxy amides using Deoxo-Fluor ...
Battilocchio, Claudio +6 more
core +2 more sources
Chemistry – A European Journal, EarlyView.A straightforward one‐step protocol enables the synthesis of bio‐based and biologically active isochromans through the Oxa‐Pictet cyclization involving diverse aldehydes, including vanillin in combination with lignin‐derivable homovanillyl alcohol, a prominent aromatic platform chemical obtainable via diol‐assisted fractionation of lignocellulose ...
Anjali Kottayi +6 more
wiley +1 more source