Results 81 to 90 of about 14,648 (255)

Synthesis, In Silico and In Vitro Evaluation of Antimicrobial and Toxicity Features of New 4-[(4-Chlorophenyl)sulfonyl]benzoic Acid Derivatives

Molecules, 2021
The multi-step synthesis, physico-chemical characterization, and biological activity of novel valine-derived compounds, i.e., N-acyl-α-amino acids, 1,3-oxazol-5(4H)-ones, N-acyl-α-amino ketones, and 1,3-oxazoles derivatives, bearing a 4-[(4-chlorophenyl ...
Theodora-Venera Apostol, Mariana Carmen Chifiriuc, Constantin Draghici, Laura-Ileana Socea, Luminita Gabriela Marutescu, Octavian Tudorel Olaru, George Mihai Nitulescu, Elena Mihaela Pahontu, Gabriel Saramet, Stefania-Felicia Barbuceanu   +9 more
doaj   +1 more source

Reaction Conditions for the Regiodivergent Direct Arylations at C2‐ or C5‐Positions of Oxazoles using Phosphine‐Free Palladium Catalysts

Advanced Synthesis and Catalysis, 2019
at C2-or C5-Positions of Abstract. Two sets of reaction conditions for the regiodivergent C2- or C5- direct arylations of oxazole are reported. In both cases, phosphine-free catalysts and inexpensive bases were employed allowing the access to the ...
Xinzhe Shi, Jean‐François Soulé, H. Doucet   +2 more
semanticscholar   +1 more source

Comparative Computational Study on the Robinson–Gabriel Synthesis and Bischler–Napieralski Reaction: Density Functional Theory Investigation of T3P‐Mediated Ring Closure

European Journal of Organic Chemistry, EarlyView.
The detailed comparison of the Bischler–Napieralski and Robinson–Gabriel reactions of tryptamides using propylphosphonic anhydride (T3P) that leads to different products in case of a small change in the substrate is provided. The computed mechanistic pathways explain why the oxoalkyl tryptamide derivative selectively reacts in a Robinson–Gabriel ...
Patrik Pollák, Mátyás Milen, Balázs Volk, Péter Ábrányi‐Balogh   +3 more
wiley   +1 more source

Azirinium ylides from α-diazoketones and 2H-azirines on the route to 2H-1,4-oxazines: three-membered ring opening vs 1,5-cyclization

Beilstein Journal of Organic Chemistry, 2015
Strained azirinium ylides derived from 2H-azirines and α-diazoketones under Rh(II)-catalysis can undergo either irreversible ring opening across the N–C2 bond to 2-azabuta-1,3-dienes that further cyclize to 2H-1,4-oxazines or reversibly undergo a 1,5 ...
Nikolai V. Rostovskii, Mikhail S. Novikov, Alexander F. Khlebnikov, Galina L. Starova, Margarita S. Avdontseva   +4 more
doaj   +1 more source

Palladium-Catalyzed Cascade Difluoroalkylation/Cyclization of N-Propargylamides: Synthesis of Oxazoles and Oxazolines.

Journal of Organic Chemistry, 2018
A palladium-catalyzed process to construct oxazoles and oxazolines with broad functional-group tolerance has been developed, and the method introduces difluoromethyl groups into heterocycles in a one-pot fashion. This system uses a carbonyl oxygen as the
Jun-Wei Ma, Qiang Wang, Xingxing Wang, Yong‐Min Liang   +3 more
semanticscholar   +1 more source

Multi‐trait responses in two marine diatoms to pH and irradiance reveal interactive effect of light and acidification, mediated by silicification

Limnology and Oceanography, EarlyView.
Abstract Ocean ecosystem shifts in response to anthropogenic climate change are impacting marine organisms, including phytoplankton. Ocean acidification and warming represent two key threats to marine phytoplankton, causing significant changes to the upper mixed layer of the ocean, reshuffling their distribution, and reorganizing their physiology and ...
Billy FitzGerald‐Lowry, Daniel Aagren Nielsen, Rebecca Julianne Duncan, Alyson May Theseira, Georgia Thompson, Katherina Petrou   +5 more
wiley   +1 more source

Characterization of a practically designed plastic scintillation plate dosimeter

Medical Physics, EarlyView.
Abstract Background Advancements in radiotherapy have enabled the use of high‐definition irradiation, leading to more precise and finely adjusted treatments in clinical settings. Nevertheless, the attainment of high resolution, an extensive measurement area, and the repeatability of dose distribution measurements persist as challenges in clinical ...
Takeshi Ohta, Yuki Nozawa, Shingo Ohira, Kanabu Nawa, Hideomi Yamashita, Keiichi Nakagawa   +5 more
wiley   +1 more source

A Systematic Review of Synthetic and Anticancer and Antimicrobial Activity of Quinazoline/Quinazolin‐4‐one Analogues

ChemistryOpen, EarlyView.
Quinazoline represents an important class of heterocycles with diverse medicinal and pharmacological significance. This review systematically examines scholarly efforts toward understanding different synthetic pathways emphasizing the role of metal and non‐metal catalysts including some miscellaneous reagents employed in the synthesis of quinazoline ...
Neha Manhas, Gobind Kumar, Sanjeev Dhawan, Talent Makhanya, Parvesh Singh   +4 more
wiley   +1 more source

Efficient synthesis of biazoles by aerobic oxidative homocoupling of azoles catalyzed by a copper(I)/2-pyridonate catalytic system. [PDF]

, 2011
A highly efficient and convenient CuCl/2-pyridonate catalytic system for oxidative homocoupling of azoles affording a biazole product has been developed.
Fujita, Ken-ichi, Yamaguchi, Ryohei, Zhu, Mingwen   +2 more
core   +1 more source

Dual-emissive 2-(2′-hydroxyphenyl)oxazoles for high performance organic electroluminescent devices: discovery of a new equilibrium of excited state intramolecular proton transfer with a reverse intersystem crossing process

Chemical Science, 2017
Dual-emission of the enol-forms and keto-forms of 2-(2′-hydroxyphenyl)oxazoles and their application in OLEDs are investigated.
Bijin Li, Linsen Zhou, Hu Cheng, Quan Huang, Jingbo Lan, Liang Zhou, J. You   +6 more
semanticscholar   +1 more source