Results 21 to 30 of about 29,607 (257)

Applications and potentials of nanopore sequencing in the (epi)genome and (epi)transcriptome era

open access: yesThe Innovation, 2021
Summary: The Human Genome Project opened an era of (epi)genomic research, and also provided a platform for the development of new sequencing technologies.
Shangqian Xie   +7 more
doaj   +1 more source

BoardION: real-time monitoring of Oxford Nanopore sequencing instruments [PDF]

open access: yesBMC Bioinformatics, 2021
Abstract Background One of the main advantages of the Oxford Nanopore Technology (ONT) is the possibility of real-time sequencing. This gives access to information during the experiment and allows either to control the sequencing or to stop the sequencing once the results have been obtained ...
Bruno, Aimeric   +2 more
openaire   +4 more sources

Universal whole-genome Oxford nanopore sequencing of SARS-CoV-2 using tiled amplicons

open access: yesScientific Reports, 2023
We developed a comprehensive multiplexed set of primers adapted for the Oxford Nanopore Rapid Barcoding library kit that allows universal SARS-CoV-2 genome sequencing.
Ruslan Kalendar   +9 more
doaj   +1 more source

Assessing the performance of the Oxford Nanopore Technologies MinION

open access: yesBiomolecular Detection and Quantification, 2015
The Oxford Nanopore Technologies (ONT) MinION is a new sequencing technology that potentially offers read lengths of tens of kilobases (kb) limited only by the length of DNA molecules presented to it. The device has a low capital cost, is by far the most portable DNA sequencer available, and can produce data in real-time.
Laver, T   +6 more
openaire   +3 more sources

Oxford Nanopore MinION Direct RNA-Seq for Systems Biology [PDF]

open access: yesBiology, 2021
Long-read direct RNA sequencing developed by Oxford Nanopore Technologies (ONT) is quickly gaining popularity for transcriptome studies, while fast turnaround time and low cost make it an attractive instrument for clinical applications. There is a growing interest to utilize transcriptome data to unravel activated biological processes responsible for ...
Mikhail A. Pyatnitskiy   +6 more
openaire   +3 more sources

Crystal structure of an invertebrate cytolysin pore reveals unique properties and mechanism of assembly

open access: yesNature Communications, 2016
Pore-forming toxins act by forming oligomeric pores in lipid membranes. Here the authors report the crystal structure of the lysenin pore, providing insights into the assembly and function of the pore in addition to suggesting that its properties make ...
Marjetka Podobnik   +18 more
doaj   +1 more source

Nanocall: an open source basecaller for Oxford Nanopore sequencing data [PDF]

open access: yesBioinformatics, 2016
Abstract Motivation The highly portable Oxford Nanopore MinION sequencer has enabled new applications of genome sequencing directly in the field. However, the MinION currently relies on a cloud computing platform, Metrichor (metrichor.com), for translating locally generated sequencing data into
Matei David   +4 more
openaire   +4 more sources

Nanopore Technology and Its Applications in Gene Sequencing

open access: yesBiosensors, 2021
In recent years, nanopore technology has become increasingly important in the field of life science and biomedical research. By embedding a nano-scale hole in a thin membrane and measuring the electrochemical signal, nanopore technology can be used to ...
Bo Lin, Jianan Hui, Hongju Mao
doaj   +1 more source

Interchromosomal template-switching as a novel molecular mechanism for imprinting perturbations associated with Temple syndrome

open access: yesGenome Medicine, 2019
Background Intrachromosomal triplications (TRP) can contribute to disease etiology via gene dosage effects, gene disruption, position effects, or fusion gene formation.
Claudia M. B. Carvalho   +21 more
doaj   +1 more source

A chromosome-level genome assembly of the redfin culter (Chanodichthys erythropterus)

open access: yesScientific Data, 2022
Measurement(s) whole genome sequencing Technology Type(s) Oxford Nanopore Sequencing Sample Characteristic - Organism Chanodichthys ...
Shihu Zhao   +7 more
doaj   +1 more source

Home - About - Disclaimer - Privacy