Results 31 to 40 of about 33,843 (263)

NanoSplicer: accurate identification of splice junctions using Oxford Nanopore sequencing

open access: yes, 2022
MOTIVATION: Long-read sequencing methods have considerable advantages for characterizing RNA isoforms. Oxford Nanopore sequencing records changes in electrical current when nucleic acid traverses through a pore.
Clark, Michael B   +5 more
core   +1 more source

The Collection of Zoosporic Eufungi at the University of Michigan (CZEUM): introducing a new repository of barcoded Chytridiomyceta and Blastocladiomycota cultures

open access: yesIMA Fungus, 2020
We formed the Collection of Zoosporic Eufungi at the University of Michigan (CZEUM) in 2018 as a cryopreserved fungal collection consolidating the University of Maine Culture Collection (UMCC, or JEL), the University of Alabama Chytrid Culture Collection
D. Rabern Simmons   +10 more
doaj   +1 more source

Phytophthora capsici genome assembly for two isolates using long-read Oxford Nanopore Technology sequencing

open access: yes, 2023
International audienceThe oomycete Phytophthora capsici is a common pathogen of the Solanaceae and Cucurbitaceae families. An improved assembly for the reference isolate LT1534 was constructed using Oxford Nanopore Technologies and Illumina data ...
Lefebvre, Véronique   +6 more
core   +1 more source

Chromosomal-level genome assembly of potato tuberworm, Phthorimaea operculella: a pest of solanaceous crops

open access: yesScientific Data, 2022
Measurement(s) whole genome sequencing Technology Type(s) Illumina NovaSeq. 6000 • Oxford Nanopore Sequencing Sample Characteristic - Organism Phthorimaea operculella Sample Characteristic - Location Yunnan Province, Southwest ...
Mengdi Zhang   +11 more
doaj   +1 more source

Assessing FOXA1-driven mRNA processing in prostate cancer with Nanopore long-read sequencing

open access: yes, 2022
Despite advances in the diagnosis and treatment of early stage of prostate cancer (PC), there are few therapeutic options for end-stage metastatic castration-resistant PC.
Matteo Cereda
core  

Detection of DNA base modifications by deep recurrent neural network on Oxford Nanopore sequencing data

open access: yesNature Communications, 2019
DNA modification generates unique electric signals in Oxford Nanopore sequencing data but the signals can be complicated to decipher. Here, the authors develop a deep learning framework, DeepMod, to detect DNA base modifications including 5mC and 6mA ...
Qian Liu   +5 more
doaj   +1 more source

Transformer‐based DNA methylation detection on ionic signals from Oxford Nanopore sequencing data

open access: yesQuantitative Biology, 2023
Transformer is an algorithm that adopts self‐attention architecture in the neural networks and has been widely used in natural language processing. In the current study, we apply Transformer architecture to detect DNA methylation on ionic signals from ...
Xiuquan Wang   +3 more
doaj   +1 more source

Gapless provides combined scaffolding, gap filling, and assembly correction with long reads

open access: yesLife Science Alliance, 2023
gapless is a new tool for combined execution of correction, scaffolding and gap filling using PacBio or Oxford Nanopore reads. Continuity, correctness, and completeness of genome assemblies are important for many biological projects. Long reads represent
Stephan Schmeing, Mark D Robinson
doaj   +1 more source

DNA origami nanopores: an emerging tool in biomedicinet

open access: yes, 2013
Editorial.The authors acknowledge support from an ERC starting grant and from Oxford Nanopore Technologies® (www.nanoporetech.com).Peer ...
Hernández-Ainsa, Silvia   +1 more
core   +1 more source

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann   +17 more
wiley   +1 more source

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