Results 101 to 110 of about 25,431 (290)

The ageing holobiont: crosstalk between telomere dynamics, oxidative stress and the gut microbiome

Biological Reviews, EarlyView.
ABSTRACT The gut tissue is at the frontline of early onset of ageing. It exhibits high cell turnover rates and rapid telomere shortening, which can have systemic effects on the developing or senescing organism. We conducted a literature review of studies on the crosstalk between telomere length dynamics, telomerase activity, oxidative stress, and gut ...
Michael L. Pepke, Søren B. Hansen, Morten T. Limborg   +2 more
wiley   +1 more source

De novo yeast genome assemblies from MinION, PacBio and MiSeq platforms

Scientific Reports, 2017
Long-read sequencing technologies such as Pacific Biosciences and Oxford Nanopore MinION are capable of producing long sequencing reads with average fragment lengths of over 10,000 base-pairs and maximum lengths reaching 100,000 base- pairs.
Francesca Giordano, Louise Aigrain, Michael A Quail, Paul Coupland, James K Bonfield, Robert M Davies, German Tischler, David K Jackson, Thomas M Keane, Jing Li, Jia-Xing Yue, Gianni Liti, Richard Durbin, Zemin Ning   +13 more
doaj   +1 more source

Hybrid correction of highly noisy Oxford Nanopore long reads using a variable-order de Bruijn graph

, 2017
MotivationThe recent rise of long read sequencing technologies such as Pacific Biosciences and Oxford Nanopore allows to solve assembly problems for larger and more complex genomes than what allowed short reads technologies. However, these long reads are
Pierre Morisse, Thierry Lecroq, Arnaud Lefebvre   +2 more
core   +1 more source

Oxford Nanopore Technology-Based Identification of an Acanthamoeba castellanii Endosymbiosis in Microbial Keratitis

Microorganisms
(1) Background: Microbial keratitis is a serious eye infection that carries a significant risk of vision loss. Acanthamoeba spp. are known to cause keratitis and their bacterial endosymbionts can increase virulence and/or treatment resistance and thus significantly worsen the course of the disease.
Sebastian Alexander Scharf, Lennart Friedrichs, Robert Bock, Maria Borrelli, Colin MacKenzie, Klaus Pfeffer, Birgit Henrich   +6 more
openaire   +3 more sources

Heteroatom‐Doped Graphdiynes and Their Applications in Photo‐/Electro‐Catalytic CO2 Conversion

Carbon Innovation, EarlyView.
This review highlights the versatile role of doped graphdiyne (GDY) in boosting CO2 conversion, where metal and non‐metal doping simultaneously tune the electronic structure, create abundant active sites, and improve charge separation, light harvesting, and CO2 adsorption.
Fangzhou Yang, Yuwei Zhang, Wai‐Yeung Wong, Linli Xu   +3 more
wiley   +1 more source

The usefulness of nanopore sequencing in whole-genome sequencing-based genotyping of Listeria monocytogenes and Salmonella enterica serovar Enteritidis

Microbiology Spectrum
Bacterial genotyping through whole-genome sequencing plays a crucial role in disease surveillance and outbreak investigations in public health laboratories.
Yu-Ping Hong, Bo-Han Chen, You-Wun Wang, Ru-Hsiou Teng, Hsiao-Lun Wei, Chien-Shun Chiou   +5 more
doaj   +1 more source

In Vivo Cytoskeletal AMPA Receptor Transport Imaging in C. elegans

Cytoskeleton, EarlyView.
ABSTRACT Long‐distance intracellular transport of ionotropic glutamate receptors (iGluRs) is essential for proper excitatory synaptic function underlying learning and memory. Many neuropsychiatric and neurodegenerative conditions have abnormal iGluR transport and trafficking, leading to an intense interest in the mechanisms and factors regulating these
Michaelis A. K., Hoerndli F. J.
wiley   +1 more source

Improving genetic diagnosis of hereditary tumor syndromes: From expanded gene panels to functional genomics

International Journal of Cancer, EarlyView.
Abstract Genetic tumor risk syndromes (genturis) contribute substantially to the overall cancer burden and provide opportunities for early detection, prevention, and individualized treatment. Yet, many affected individuals remain undiagnosed due to restrictive testing criteria and challenges in variant interpretation.
Mayra Sauer, Morghan C. Lucas, Vitus Prokosch, Thomas Keßler, Thomas Risch, Andreas Laner, Jan Henkel, Anna Benet‐Pagès, Ariane Hallermayr, Verena Steinke‐Lange, Elke Holinski‐Feder, Barbara Klink   +11 more
wiley   +1 more source

Rapid Nanopore Sequencing to Identify Bacteria Causing Prosthetic Joint Infections

Background/Objectives: The diagnosis of prosthetic joint infection remains difficult. Microbiological cultures frequently have false-positive and false-negative results.
Charlotte Hulme, Cool, Paul, Hollie Wilkinson, Hulme, Charlotte, Wright, Karina, Perry, Jade, Niall Steele, Townsend, Rob, McCarthy, Helen S., Rob Townsend, Helen S. McCarthy, Steele, Niall, Jade Perry, Wilkinson, Hollie, Benjamin Burston, Burston, Benjamin, Karina Wright, Paul Cool   +17 more
core   +1 more source

Improving the diagnosis of cassava mosaic begomoviruses using Oxford Nanopore Technology sequencing

Scientific Reports
Abstract Cassava mosaic disease (CMD), caused by begomoviruses such as African cassava mosaic virus (ACMV) and East African cassava mosaic virus (EACMV), poses a threat to food security in sub-Saharan Africa. Conventional PCR assays often fail to detect viral strains in symptomatic plants due to high genetic variability and ...
Combala, Mariam, Tibiri, Ezechiel B., Pita, Justin S., Eni, Angela O., Sawadogo, Seydou, Name, Pakyendou E., Zongo, Saïdou, Kouhoumouri, Poupouanou, Sagnon, Adama, Efekemo, Oghenevwairhe P., Onile-ere, Olabode, Oppong, Allen, Ndougonna, Cyrielle, Tiendrébéogo, Fidèle   +13 more
openaire   +3 more sources