Results 71 to 80 of about 747,150 (312)
Liver Damage in Patients with HCV/HIV Coinfection Is Linked to HIV-Related Oxidative Stress [PDF]
, 2016 HIV infection aggravates the progression of liver damage in HCV-coinfected patients, with the underlying pathogenesis being multifactorial. Although high level of oxidative stress has been observed frequently in patients infected with HIV or HCV, the ...
Shen, Tao +4 more
core +1 more source
Oxidative RNA Damage and Neurodegeneration
Current Medicinal Chemistry, 2007 Although cellular RNA should be subject to the same oxidative insults as DNA and other cellular macromolecules, oxidative damage to RNA has not been a major focus in investigating the magnitude and the biological consequences of the free radical damage.
Nunomura, Akihiko +4 more
openaire +3 more sources
Potential of cyclodipeptides in combating oxidative stress in chronic diseases
Pharmacological ResearchOxidative stress results from an imbalance between free radicals—such as reactive oxygen species (ROS) and reactive nitrogen species (RNS)—and the body’s antioxidant defenses.
Hamsaletchumi Rajan +4 more
doaj +1 more source
The Nervous System Cytoskeleton under Oxidative Stress
Diseases, 2013 Oxidative stress is a key mechanism causing protein aggregation, cell death and neurodegeneration in the nervous system. The neuronal cytoskeleton, that is, microtubules, actin filaments and neurofilaments, plays a key role in defending the nervous ...
John Gardiner, Robyn Overall, Jan Marc
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
, 2020 Introduction Cisplatin is one of the most frequently used chemotherapeutics, which is known to cause both tumor and normal lung tissue damage through the generation of free radicals and cells apoptosis/necrosis. Melatonin is a neurohormone that regulates
Ksenija Turković +9 more
core +1 more source
Age Associated Oxidative Damage in Lymphocytes [PDF]
Oxidative Medicine and Cellular Longevity, 2010 Lymphocytes are an important immunological cell and have been played a significant role in acquired immune system; hence, may play in pivotal role in immunosenescence. Oxidative stress has been reported to increase in elderly subjects, possibly arising from an uncontrolled production of free radicals with aging and decreased antioxidant defenses.
Gautam, Nandeslu +5 more
openaire +2 more sources
Mitochondrial DNA is a sensitive surrogate and oxidative stress target in oral cancer cells.
PLoS ONECellular oxidative stress mediated by intrinsic and/or extrinsic reactive oxygen species (ROS) is associated with disease pathogenesis. Oxidative DNA damage can naturally be substituted by mitochondrial DNA (mtDNA), leading to base lesion/strand break ...
Jingyu Tan, Xinlin Dong, Haiwen Liu
doaj +1 more source
Ecotoxicology and Environmental SafetyFluorosis is a systemic disorder with primary manifestations including skeletal and dental fluorosis, where skeletal fluorosis is associated with cartilage lesions.
Fang-fang Yu +14 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source