Results 21 to 30 of about 8,483 (210)
Molecules, 2021 A synthetic route for the enantioselective construction of the tetracyclic spiro[indolizidine-1,3′-oxindole] framework present in a large number of oxindole alkaloids, with a cis H-3/H-15 stereochemistry, a functionalized two-carbon substituent at C-15 ...
Nihan Yayik +4 more
doaj +1 more source
Synthesis and solid-state characterisation of 4-substituted methylidene oxindoles [PDF]
, 2013 Background 4-substituted methylidene oxindoles are pharmacologically important. Detailed analysis and comparison of all the interactions present in crystal structures is necessary to understand how these structures arise.
FH Allen +22 more
core +1 more source
Molecules, 2023 Thirty-three 1,3-dihydro-2H-indolin-2-one derivatives bearing α, β-unsaturated ketones were designed and synthesized via the Knoevenagel condensation reaction.
Taohua Pan +6 more
doaj +1 more source
Highly Efficient Oxindole‐Based Molecular Photoswitches
Chemistry – A European Journal, 2023 Abstract3‐Benzylidene‐indoline‐2‐ones play a prominent role in the pharmaceutical industry due to the diverse biomedical applications of oxindole heterocycles. Despite the extensive reports on their biological properties, these compounds have hardly been studied for their photochemical activity.
Daniel Doellerer +4 more
openaire +4 more sources
Palladium-Catalyzed α-Arylation of Carboxylic Acids and Secondary Amides via a Traceless Protecting Strategy. [PDF]
, 2019 A novel traceless protecting strategy is presented for the long-standing challenge of conducting the palladium-catalyzed α-arylation of carboxylic aids and secondary amides with aryl halides.
Hartwig, John F, He, Zhi-Tao
core +1 more source
Molecules, 2019 The Pd-catalyzed intramolecular carbene C−H insertion of α-diazo-α-(methoxycarbonyl)acetamides to prepare oxindoles as well as β-lactams was studied.
Daniel Solé +4 more
doaj +1 more source
Photochemical Deracemization of 3‐Substituted Oxindoles
Angewandte Chemie, 2023 AbstractRacemic 3‐substituted oxindoles were successfully converted into enantiomerically pure or enriched material (up to 99 % ee) upon irradiation at λ=366 nm in the presence of a chiral benzophenone catalyst (10 mol %). The photochemical deracemization process allows predictable editing of the stereogenic center at carbon atom C3.
Johannes Großkopf +2 more
openaire +3 more sources
Molecules, 2013 An efficient approach for the synthesis of 3-substituted-3-hydroxy-2-oxindoles has been achieved via an aldol reaction of α,β-unsaturated ketones and isatins using arginine as an organocatalyst.
Tingting Yan +4 more
doaj +1 more source
Alkaloid inspired spirocyclic oxindoles from 1,3-dipolar cycloaddition of pyridinium ylides [PDF]
, 2013 Cycloaddition reactions between pyridinium ylides and 3-alkenyl oxindoles that proceed in high yield and with very good regio- and diastereoselectivity are reported. The resulting cycloadducts have the same stereochemistry of biologically active oxindole
Castledine, Richard A. +5 more
core +3 more sources
Molecules, 2020 New D-π-A configured organic sensitizers featuring halogen-substituted oxindole-bridged acceptor units have been synthesized for dye-sensitized solar cells applications.
Yogesh S. Tingare +5 more
doaj +1 more source