Results 71 to 80 of about 8,483 (210)

Metal fluorides, metal chlorides and halogenated metal oxides as Lewis acidic heterogeneous catalysts. Providing some context for nanostructured metal fluorides [PDF]

, 2017
Aspects of the chemistry of selected metal fluorides, which are pertinent to their real or potential use as Lewis acidic, heterogeneous catalysts, are reviewed.
Lennon, David, Winfield, John M.
core   +1 more source

Visible light mediated aerobic oxidative hydroxylation of 2-oxindole-3-carboxylate esters: an alternative approach to 3-hydroxy-2-oxindoles

Heterocyclic Communications, 2020
A convenient aerobic oxidative hydroxylation of 3-substituted oxindoles under mild reaction conditions is described herein. This process was accomplished by the activation of molecular oxygen in the air in the presence of a photocatalyst under the ...
Wang Jinge, Osman Siyitemer, Lu Xinjiang, Chen Junyi, Xia Xu-Dong   +4 more
doaj   +1 more source

Catalyst-Controlled Chemoselective Arylation of 2-Aminobenzimidazoles [PDF]

, 2012
What N would you like? The chemoselective and complementary Pd- and Cu-catalyzed N-arylation of 2-aminobenzimidazoles is described. Selective N-arylation of the amino group was achieved with a Pd-catalyzed method, while selective N-arylation of azole ...
Altman, Altman, Anderson, Antilla, Carpenter, Cee, Da Settimo, Deng, Evindar, Fagan, Fukuda, Hartwig, Huang, Iemura, Kiyomori, Klapars, Koizumi, Lan, Liang, Liu, Maiti, McGowan, Monnier, Murphy, Paget, Peterson, Shafir, Surry, Ueda, Ueda, Varming, Wan, Wang, Wu, Yin, Zhang, Zhong   +36 more
core   +1 more source

A Flavonoid‐Rich Extract of Scoparia dulcis L. Exhibits Antiviral Activity against Herpes Virus Type 1

Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.
ABSTRACT This study investigated the phytochemical profile, cytotoxicity, and anti‐herpetic activity of the hydroethanolic extract from Scoparia dulcis L. aerial parts. Mass spectrometry revealed the presence of 15 compounds. The extract showed low cytotoxicity in Vero cells, maintaining over 80% viability at concentrations up to 250 µg/mL.
Francisco Leandro Medeiros de Lucena Jales, Emerson Michell da Silva Siqueira, Renato Dantas‐Medeiros, Edilane Rodrigues Dantas de Araújo, Jovelina Samara Ferreira Alves, Hugo Alexandre de Oliveira Rocha, Norberto Peporine Lopes, Leandro de Santis Ferreira, Emanuella de Aragão Tavares, Silvana Maria Zucolotto   +9 more
wiley   +1 more source

Alkenyl oxindole is a novel PROTAC moiety that recruits the CRL4DCAF11 E3 ubiquitin ligase complex for targeted protein degradation.

PLoS Biology
Alkenyl oxindoles have been characterized as autophagosome-tethering compounds (ATTECs), which can target mutant huntingtin protein (mHTT) for lysosomal degradation. In order to expand the application of alkenyl oxindoles for targeted protein degradation,
Ying Wang, Tianzi Wei, Man Zhao, Aima Huang, Fan Sun, Lu Chen, Risheng Lin, Yubao Xie, Ming Zhang, Shiyu Xu, Zhihui Sun, Liang Hong, Rui Wang, Ruilin Tian, Guofeng Li   +14 more
doaj   +1 more source

Bioinspired Light‐Driven Organic Rotary Molecular Systems

ChemistryEurope, Volume 4, Issue 1, January 2026.
This review explores the evolution of bioinspired light‐driven rotary molecular systems (RMSs), highlighting the integration of natural chromophore‐based fragments to enhance quantum efficiency, photostability, and biocompatibility. Key strategies to optimize photochemical performance and broaden functional applications are discussed, providing a ...
Lidia Hortigüela, Sara P. Morcillo
wiley   +1 more source

The tandem radical route to indole alkaloids: an unusual rearrangement reaction [PDF]

, 2006
Cyclisation of the precursor 6 under standard radical conditions yields the tetracyclic structure 7 which represents the core of a number of indole alkaloids along with the novel tetracycle ...
Hilton, ST, Jones, K
core   +1 more source

Decoding Urease Inhibition: A Comprehensive Review of Inhibitor Scaffolds

ChemMedChem, Volume 21, Issue 2, January 2026.
Representative functional groups known for urease inhibition are reviewed within diverse scaffolds using structure–activity analyses to identify features associated with high inhibitory activity. Urease is a metalloenzyme produced by a wide range of organisms and plays a critical role in nitrogen microbial metabolism by catalyzing the hydrolysis of ...
Nuno Martinho, Natália Aniceto
wiley   +1 more source

Palladium-Catalyzed Dehydrogenative Coupling: An Efficient Synthetic Strategy for the Construction of the Quinoline Core [PDF]

, 2017
Palladium-catalyzed dehydrogenative coupling is an efficient synthetic strategy for the construction of quinoline scaffolds, a privileged structure and prevalent motif in many natural and biologically active products, in particular in marine alkaloids ...
Carral Menoyo, Asier, Lete Expósito, María Esther, Martínez Nunes, Mikel, Ortiz de Elguea Flecha, Verónica, Sotomayor Anduiza, María Nuria   +4 more
core   +2 more sources

A Scalable and Sustainable Synthesis of Indirubin Frameworks Enabled by Deep Eutectic Solvents

ChemSusChem, Volume 19, Issue 1, January 2026.
A sustainable protocol for the synthesis of indirubin in a choline chloride/urea deep eutectic solvent at 70°C under air affords the product in 70% yield without chromatography. The method is robust, scalable to pilot scale, and enables late‐stage functionalization, granting access to a wide range of indirubin derivatives. CHEM21 green metrics validate
Biagio Delvecchio, Luciana Cicco, Andrea Nicola Paparella, Gaetano Di Salvo, Filippo Maria Perna, Vito Capriati   +5 more
wiley   +1 more source