Results 21 to 30 of about 28,231 (235)

Oxycodone intravenous for acute pain management in modified radical mastectomy

Bali Journal of Anesthesiology, 2020
Oxycodone hydrochloride is a semisynthetic opioid which extracted from the baine plant, with a similar analgesic potency compared with morphine. Although oxycodone was introduced in 1917, the global use of oxycodone in acute postoperative management ...
Tjokorda Gde Agung Senapathi, I Putu Pramana Suarjaya, I Wayan Aryabiantara, Adinda Putra Pradhana, Amalia Margaretha Berhimpon   +4 more
doaj   +1 more source

Suvorexant, an FDA-approved dual orexin receptor antagonist, reduces oxycodone self-administration and conditioned reinstatement in male and female rats

Frontiers in Pharmacology, 2023
Background: The Department of Health and Human Services reports that prescription pain reliever (e.g., oxycodone) misuse was initiated by 4,400 Americans each day in 2019.
Jessica M. Illenberger, Francisco J. Flores-Ramirez, Alessandra Matzeu, Barbara J. Mason, Rémi Martin-Fardon   +4 more
doaj   +1 more source

S-ketamine in patient-controlled analgesia reduces opioid consumption in a dose-dependent manner after major lumbar fusion surgery: A randomized, double-blind, placebo-controlled clinical trial.

PLoS ONE, 2021
BackgroundSpinal fusion surgery causes severe pain. Strong opioids, commonly used as postoperative analgesics, may have unwanted side effects. S-ketamine may be an effective analgesic adjuvant in opioid patient-controlled analgesia (PCA).
Elina C V Brinck, Taru Virtanen, Sanna Mäkelä, Venla Soini, Ville-Veikko Hynninen, Jukka Mulo, Urmas Savolainen, Juho Rantakokko, Kreu Maisniemi, Antti Liukas, Klaus T Olkkola, Vesa Kontinen, Pekka Tarkkila, Marko Peltoniemi, Teijo I Saari   +14 more
doaj   +1 more source

Oxycodone in mastectomy surgery

Bali Journal of Anesthesiology, 2020
The pharmacological effects of oxycodone and morphine are close. The analgesic potency between oxycodone and morphine is presumed to have a 1:1 ratio. Fentanyl-to-morphine ratio was 1:100. The plasma levels of oxycodone are more active than morphine. The
Putu Pramana Suarjaya, Cynthia Dewi Sinardja, Aninda Tanggono   +2 more
doaj   +1 more source

Negative Affective States Are Not Detected in Rats Following an Intravenous Self-Administration Regimen Leading to Incubation of Oxycodone Craving. [PDF]

Addict Biol
This study asked whether negative affective states are detected in rats after protracted abstinence from an oxycodone self‐administration regimen leading to incubation of craving. After more than 40 days of abstinence, when incubation is robust, we found no differences between saline and oxycodone rats in tests of negative affect.
Wunsch AM, Mount KA, Guzman A, Kawa AB, Westlake JG, Kuhn HM, Beutler MM, Wolf ME.   +7 more
europepmc   +2 more sources

Intravenous Oxycodone Versus Other Intravenous Strong Opioids for Acute Postoperative Pain Control: A Systematic Review of Randomized Controlled Trials

Pain and Therapy, 2019
Introduction Optimal pain management is crucial to the postoperative recovery process. We aimed to evaluate the efficacy and safety of intravenous oxycodone with intravenous fentanyl, morphine, sufentanil, pethidine, and hydromorphone for acute ...
Milton Raff, Anissa Belbachir, Salah El-Tallawy, Kok Yuen Ho, Eric Nagtalon, Amar Salti, Jeong-Hwa Seo, Aida Rosita Tantri, Hongwei Wang, Tianlong Wang, Kristal Cielo Buemio, Consuelo Gutierrez, Yacine Hadjiat   +12 more
doaj   +1 more source

Oxycodone-related deaths in Sweden 2006-2018

, 2022
Aim: To identify and characterize oxycodone related deaths in Sweden from 2006 to 2018 and to compare them to other opioid-related deaths. Methods: To assess the factors contributing to the deaths, we used multinomial logistic regression to compare ...
Ramstedt, M,, Hjelmstrom, P, Hjelmstrom, Peter,, Ramstedt, Mats, Hjelmstrom, Peter, Agren, G, Fugelstad, Anna, Thiblin, Ingemar,, Thiblin, Ingemar, Fugelstad, Anna,, Ramstedt, Mats,, Thiblin, Ingmar, Fugelstad, A,, Agren, Gunnar, Thiblin, I, Agren, Gunnar,, Gunnar Ågren, Anna Fugelstad, Mats Ramstedt, Ingmar Thiblin, Peter Hjelmström   +20 more
core   +1 more source

Metabolism of oxycodone in human hepatocytes from different age groups and prediction of hepatic plasma clearance

Frontiers in Pharmacology, 2012
Oxycodone is commonly used to treat severe pain in adults and children. It is extensively metabolized in the liver in adults, but the maturation of metabolism is not well understood. Our aim was to study the metabolism of oxycodone in cryopreserved human
Timo eKorjamo, Ari eTolonen, Veli-Pekka eRanta, Miia eTurpeinen, Hannu eKokki, Hannu eKokki   +5 more
doaj   +1 more source

Oxycodone does not affect placental circulatory physiology during the early first stage of labor—A randomized trial

Acta Obstetricia et Gynecologica Scandinavica, 2023
Introduction Opioids are used for pain relief during the first stage of labor. Oxycodone can cause maternal hypotension that may modify utero‐ and fetoplacental circulatory physiology.
Leena Alanne, Hannu Kokki, Anu Mykkänen, Maija‐Riitta Ordén, Valtteri Rinne, Juha Räsänen, Merja Kokki   +6 more
doaj   +1 more source

Molecularly Imprinted Electrochemical Sensor Based on Poly (O-Phenylenediamine) for Sensitive Detection of Oxycodone in Water

Electrochem, 2023
This work was aimed at the development of a sensitive electrochemical detection method for oxycodone in water. Molecularly imprinted electrodes were formed by electro-polymerization process using o-phenylenediamine as a monomer.
Pranaya Charkravarthula, Amos Mugweru
doaj   +1 more source