Results 11 to 20 of about 12,832 (200)

Genome-wide analysis of oxylipins and oxylipin profiles in a pediatric population

Frontiers in Nutrition, 2023
BackgroundOxylipins are inflammatory biomarkers derived from omega-3 and-6 fatty acids implicated in inflammatory diseases but have not been studied in a genome-wide association study (GWAS).
Teresa Buckner, Teresa Buckner, Randi K. Johnson, Randi K. Johnson, Lauren A. Vanderlinden, Patrick M. Carry, Patrick M. Carry, Alex Romero, Suna Onengut-Gumuscu, Wei-Min Chen, Soojeong Kim, Oliver Fiehn, Brigitte I. Frohnert, Tessa Crume, Wei Perng, Katerina Kechris, Marian Rewers, Jill M. Norris   +17 more
doaj   +5 more sources

Oxylipins in plastidial retrograde signaling

Redox Biology, 2020
Oxylipins (compounds derived from the oxidation of polyunsaturated fatty acids) are essential in retrograde signaling emanating from plastids to the nucleus during plant developmental and stress responses. In this graphical review, we provide an overview
Paula Muñoz, Sergi Munné-Bosch
doaj   +3 more sources

Reduced triacylglycerols and lipid droplets are associated with resilience to Alzheimer's disease. [PDF]

Alzheimers Dement
Abstract INTRODUCTION Although it has become clear that alterations in lipid metabolism are associated with Alzheimer's disease (AD), it is unclear how they contribute to both cognitive decline and the pathophysiology of AD. METHODS Lipidomics and activity‐based protein profiling (ABPP) were performed in the frontal cortex of control, AD and resilient ...
van der Vliet D, de Vries LE, Di X, Wever D, de Jong B, van der Meij MTC, van der Peet M, Harms AC, Hankemeier T, Swaab DF, Huitinga I, Verhaagen J, van der Stelt M.   +12 more
europepmc   +2 more sources

Axial and radial oxylipin transport [PDF]

Plant Physiology, 2015
Jasmonates are oxygenated lipids (oxylipins) that control defense gene expression in response to cell damage in plants. How mobile are these potent mediators within tissues? Exploiting a series of 13-lipoxygenase (13-lox) mutants in Arabidopsis (Arabidopsis thaliana) that displays impaired jasmonic acid (JA) synthesis in specific cell types and using ...
Gasperini, Debora, Chauvin, Adeline, Acosta, Ivan F., Kurenda, Andrzej, Stolz, Stéphanie, Chételat, Aurore, Wolfender, Jean-Luc, Farmer, Edward E   +7 more
openaire   +4 more sources

Oxylipins in fungi [PDF]

The FEBS Journal, 2011
In nearly every living organism, metabolites derived from lipid peroxidation, the so‐called oxylipins, are involved in regulating developmental processes as well as environmental responses. Among these bioactive lipids, the mammalian and plant oxylipins are the best characterized, and much information about their physiological role and biosynthetic ...
Florian, Brodhun, Ivo, Feussner
openaire   +2 more sources

The Quantitative Profiling of Oxylipins from Arachidonic Acid by LC-MS/MS in Feces at Birth 3 Days and 21 Days of Piglets

Metabolites, 2022
Oxylipins (also called eicosanoids) are enzymatically or nonenzymatically generated by oxidation of arachidonic acid (ARA) and are major mediators of ARA effects in the body.
Ningning Huang, Xiangchen Liu, Xiaoqi Pei, Jian Peng, Hongkui Wei   +4 more
doaj   +1 more source

Effect of omega-3 fatty acid ethyl esters on the oxylipin composition of lipoproteins in hypertriglyceridemic, statin-treated subjects. [PDF]

PLoS ONE, 2014
Oxylipins mediate inflammation, vascular tension, and more. Their presence in lipoproteins could explain why lipoproteins mediate nearly identical activities.To determine how oxylipins are distributed in the lipoproteins of hypertriglyceridemic subjects,
John W Newman, Theresa L Pedersen, Verdayne R Brandenburg, William S Harris, Gregory C Shearer   +4 more
doaj   +1 more source

Defining the Intestinal eCBome and Oxylipin Signaling Systems in a TDP-43 Mouse Model of Frontotemporal Dementia. [PDF]

FASEB J
TDP‐43 overexpressing mice, a genetic model of frontotemporal dementia, exhibit dramatic changes in their small intestinal endocannabinoidome members, in terms of both altered concentrations of lipid mediators and expression of some of their receptors (Cnr1, Gpr119, Gpr55, Pparg) and metabolic enzymes (Napepld, Faah). Also, the levels of some oxylipins
Mir HD, Giorgini G, Santos-García I, Dumais E, Rodríguez-Cueto C, de Lago E, Silvestri C, Flamand N, Fernández-Ruiz J, Di Marzo V.   +9 more
europepmc   +2 more sources

Frataxin deficiency increases cyclooxygenase 2 and prostaglandins in cell and animal models of Friedreich's ataxia [PDF]

, 2014
© The Author 2014. Published by Oxford University Press This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution,
Al-Mahdawi, Al-Mahdawi, Block, Campuzano, Campuzano, Capdevila, Capdevila, Castaldo, Chantrel-Groussard, Chen, Cossee, Dewitt, Durr, Durr, Feng, Genki Hayashi, Gino Cortopassi, Harding, John W. Newman, Kang, Koeppen, Li, Liang, Lin, Lu, Mark Pook, Masi, Michael, Miranda, Node, O'Flaherty, Paupe, Piemonte, Piro, Praticò, Qin, Ristow, Rojo, Samuelsson, Sanchez-Mejia, Schulz, Shan, Shi, Shin, Small, Smith, Strokin, Tan, Teismann, Theresa L. Pedersen, Tian, Wardlaw, Wong, Wong, Xi, Yan, Yan Shen, Zhang   +57 more
core   +4 more sources

Detoxification Cytochrome P450s (CYPs) in Families 1–3 Produce Functional Oxylipins from Polyunsaturated Fatty Acids

Cells, 2022
This manuscript reviews the CYP-mediated production of oxylipins and the current known function of these diverse set of oxylipins with emphasis on the detoxification CYPs in families 1–3.
Jazmine A. Eccles, William S. Baldwin
doaj   +1 more source