Results 41 to 50 of about 9,329 (194)

Role of Oxylipins in the Inflammatory-Related Diseases NAFLD, Obesity, and Type 2 Diabetes

Metabolites, 2022
Oxygenated polyunsaturated fatty acids (oxylipins) are bioactive molecules established as important mediators during inflammation. Different classes of oxylipins have been found to have opposite effects, e.g., pro-inflammatory prostaglandins and anti ...
Mariya Misheva, Jethro Johnson, James McCullagh   +2 more
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Ibuprofen alters epoxide hydrolase activity and epoxy-oxylipin metabolites associated with different metabolic pathways in murine livers

Scientific Reports, 2021
Over the last decade oxylipins have become more recognized for their involvement in several diseases. Non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen are known to inhibit cyclooxygenase (COX) enzymes, but how NSAIDs affect oxylipins, in ...
Shuchita Tiwari, Jun Yang, Christophe Morisseau, Blythe Durbin-Johnson, Bruce D. Hammock, Aldrin V. Gomes   +5 more
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EtOH-mediated alterations in liver oxylipins. [PDF]

, 2018
A: Summary of changes in hepatic ω-6 and ω-3 PUFA-derived oxylipins in response to EtOH exposure. B: A working model wherein multiple ω-6-derived oxylipins (to the left) facilitate liver injury via distinct mechanisms.
Dennis R. Warner (5793875), Xiang Zhang (19800), Jeffrey B. Warner (5793881), Craig J. McClain (470562), Md Aminul Islam Prodhan (5793884), Ariel E. Feldstein (284627), Irina A. Kirpich (5793887), Huilin Liu (346783), Shubha Ghosh Dastidar (5793878), Xinmin Yin (284781), Russell A. Prough (4163308), Bin Gao (191656)   +11 more
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Influence of Dietary n-3 Long Chain Polyunsaturated Fatty Acid Intake on Oxylipins in Erythrocytes of Women with Rheumatoid Arthritis

Molecules, 2023
Oxylipins derived from n-3 fatty acids are suggested as the link between these fatty acids and reduced inflammation. The aim of the present study was to explore the effect of a randomized controlled cross-over intervention on oxylipin patterns in ...
Helen M. Lindqvist, Anna Winkvist, Inger Gjertsson, Philip C. Calder, Aaron M. Armando, Oswald Quehenberger, Roxana Coras, Monica Guma   +7 more
doaj   +1 more source

Plant-pathogen interactions: underestimated roles of phyto-oxylipins [PDF]

, 2020
peer reviewedPlant oxylipins are produced under a wide range of stress conditions, and even though they are well known to activate stress-related signalling pathways, the non-signalling roles of phyto-oxylipins are poorly understood.
Lins, Laurence, Mongrand, Sébastien, Deboever, Estelle, Fauconnier, Marie-Laure, Deleu, Magali   +4 more
core   +1 more source

Potential of Plasma Oxylipin Signature to Better Understand the Relationships between Diet, Fatty Acids and Oxylipins in Healthy Individuals: New Insights from Two Independent Cohort Studies

Proceedings
Eicosanoids and other oxylipins represent a superfamily of bioactive lipids involved in the regulation of crucial biological processes such as inflammation, blood clotting or endothelial reactivity.
Cécile Gladine, Nils Schebb, Mathilde Touvier, Arne Astrup, Philip Calder, Andrzej Szuba, John Newman   +6 more
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Lipids in Aspergillus flavus-maize interaction

Frontiers in Microbiology, 2014
In sSome filamentous fungi, the pathways related to the oxidative stress and oxylipins production are involved both in the process of host-recognition of the host that and in the pathogenic phase. In fact, recent studies have shown that the production of
Massimo eReverberi, marzia escarpari, emanuela ecamera, matteo eludovici, chiara enobili, marta epunelli, marco ezaccaria, valeria escala, corrado efanelli, anna adele fabbri   +9 more
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Total Synthesis of DHA and DPAn-3 Non-Enzymatic Oxylipins [PDF]

, 2022
International audienceOxylipins are formed in vivo from polyunsaturated fatty acids (PUFAs). A large structural variety of compounds is grouped under the term oxylipins, which differ from their formation mechanism (involving enzymes or not), as well as ...
Guy, Alexandre, Galano, Jean-Marie, Merad, Jérémy, Durand, Thierry, Degrange, Thomas, Bultel-Poncé, Valérie, Oger, Camille, Reversat, Guillaume   +7 more
core   +1 more source

Development of a desorption electrospray ionization –multiple-reaction-monitoring mass spectrometry (DESI-MRM) workflow for spatially mapping oxylipins in pulmonary tissue [PDF]

Oxylipins are a class of low abundant lipids formed via oxygenation of fatty acids. These compounds include potent signaling molecules (e.g., octadecanoids, eicosanoids) that can exert essential functions in the pathophysiology of inflammatory diseases ...
Mikael, Adner, Matthew, Smith, Jesper, Säfholm, Mu, Nie, Craig, Wheelock   +4 more
core   +1 more source

Bioactive C₁₇ and C₁₈ Acetylenic Oxylipins from Terrestrial Plants as Potential Lead Compounds for Anticancer Drug Development

Molecules, 2020
Bioactive C17 and C18 acetylenic oxylipins have shown to contribute to the cytotoxic, anti-inflammatory, and potential anticancer properties of terrestrial plants.
Lars Porskjær Christensen
doaj   +1 more source