Results 41 to 50 of about 10,743 (200)

Serum levels of oxylipins in achilles tendinopathy: an exploratory study. [PDF]

PLoS ONE, 2015
BACKGROUND:Linoleic acid-derived oxidation products are found in experimental pain models. However, little is known about the levels of such oxylipins in human pain.
Sandra Gouveia-Figueira, Malin L Nording, Jamie E Gaida, Sture Forsgren, Håkan Alfredson, Christopher J Fowler   +5 more
doaj   +1 more source

Multifunctional Enzymes in Oxylipin Metabolism

ChemBioChem, 2008
Fingers in lots of pies: For the first time a member of the CYP74 enzyme subfamily (9‐AOS) from tomato has been shown by chemical and analytical approaches to catalyze multiple reactions. These multifunctional properties of 9‐AOS from the oxylipin‐forming lipoxygenase (LOX) pathway raise several new questions on lipid‐derived signaling.
Wasternack, Claus, Feussner, Ivo
openaire   +3 more sources

Fungal and bacterial oxylipins are signals for intra- and inter-cellular communication within plant disease

Frontiers in Plant Science, 2022
Lipids are central at various stages of host–pathogen interactions in determining virulence and modulating plant defense. Free fatty acids may act as substrates for oxidizing enzymes [e.g., lipoxygenases (LOXs) and dioxygenases (DOXs)] that synthesize ...
Marzia Beccaccioli, Nicoletta Pucci, Manuel Salustri, Marco Scortichini, Marco Zaccaria, Babak Momeni, Stefania Loreti, Massimo Reverberi, Valeria Scala   +8 more
doaj   +1 more source

Conditionally Significant eQTL and TWAS Analyses Identify MsRD26 as a Major Candidate Positive Regulator of Salt Tolerance in Medicago sativa L

Advanced Science, EarlyView.
Salt stress significantly impacts plant growth. Through population transcriptome, eQTL and TWAS analyses, we identified several candidate genes potentially associated with salt stress response. Functional assays suggested that some of these genes may contribute to salt tolerance.
Lin Chen, Yuqi Zhang, Xinyue Ma, Jinpeng Bi, Fei He, Li Zhao, Haiyue Lei, Zhengqin Xiao, Xue Wang, Tiejun Zhang, Ruicai Long, Junmei Kang, Qingchuan Yang   +12 more
wiley   +1 more source

Oxylipins Associated with D3-Creatine Muscle Mass/Weight and Physical Performance among Community-Dwelling Older Men [PDF]

, 2022
Poor physical function is highly prevalent with aging, and strongly associated with D3-creatine muscle mass/weight. Using metabolomics, we previously identified several triglycerides consisting mostly of polyunsaturated fatty acids that were higher in ...
Newman, Anne B, Lane, Nancy E., Nancy E. Lane, Cawthon, Peggy M, Anne B. Newman, Megan M. Marron, Eric S. Orwoll, Cauley, Jane A., Marron, Megan M, Peggy M. Cawthon, Lane, Nancy E, Jane A. Cauley, Orwoll, Eric S., Newman, Anne B., Cauley, Jane A, Marron, Megan M., Cawthon, Peggy M., Orwoll, Eric S, Marron, Megan M,; Orwoll, Eric S,; Cawthon, Peggy M,; Lane, Nancy E,; Newman, Anne B,; Cauley, Jane A,   +18 more
core   +1 more source

Identification of omega-3 oxylipins in human milk-derived extracellular vesicles with pro-resolutive actions in gastrointestinal inflammation

Frontiers in Immunology, 2023
IntroductionPremature infants (PIs) are at risk of suffering necrotizing enterocolitis (NEC), and infants consuming human milk (HM) show a lower incidence than infants receiving formula.
Marta Gómez-Ferrer, Elena Amaro-Prellezo, Abel Albiach-Delgado, Isabel Ten-Domenech, Julia Kuligowski, Pilar Sepúlveda, Pilar Sepúlveda, Pilar Sepúlveda, Pilar Sepúlveda   +8 more
doaj   +1 more source

USP4‐Dependent CHAF1B Stabilization Regulates Distinct SETDB1 Ubiquitin States Linked to AKT T308 Signaling and Lipogenic Remodeling in HCC

Advanced Science, EarlyView.
USP4 stabilizes CHAF1B by limiting K48‐linked ubiquitination. Stabilized CHAF1B supports UHRF1‐associated K63‐linked SETDB1 ubiquitination and cytoplasmic redistribution, whereas CHAF1B loss favors VHL‐dependent K11‐associated degradative ubiquitination and proteasomal loss of SETDB1.
Saiyan Bian, Yun Tong, Wenkai Ni, Zhangzhi Tang, Weiting Chen, Kexin Ma, Lihan Jiang, Jiayu Shao, Xuyang He, Wenjie Zheng   +9 more
wiley   +1 more source

Epoxyalcohol Synthase Branch of Lipoxygenase Cascade

Current Issues in Molecular Biology
Oxylipins are one of the most important classes of bioregulators, biosynthesized through the oxidative metabolism of unsaturated fatty acids in various aerobic organisms.
Yana Y. Toporkova, Elena O. Smirnova, Svetlana S. Gorina   +2 more
doaj   +1 more source

Oxylipin Response to Acute and Chronic Exercise: A Systematic Review

Metabolites, 2020
Oxylipins are oxidized compounds of polyunsaturated fatty acids that play important roles in the body. Recently, metabololipidomic-based studies using advanced mass spectrometry have measured the oxylipins generated during acute and chronic physical ...
Étore F. Signini, David C. Nieman, Claudio D. Silva, Camila A. Sakaguchi, Aparecida M. Catai   +4 more
doaj   +1 more source

PIAS3 CircRNA‐Loaded Lipid Nanoparticles Restore ALOX15 SUMOylation to Suppress Cementoblast Ferroptosis and Attenuate Orthodontically Induced Root Resorption

Advanced Science, EarlyView.
Orthodontic compression suppresses PIAS3 expression in cementoblasts, impairing ALOX15 SUMOylation and ubiquitin‐mediated degradation, which leads to ALOX15 accumulation, lipid peroxidation, ferroptosis, and osteoclastogenesis. Local delivery of PIAS3 circRNA‐loaded lipid nanoparticles restores the PIAS3–ALOX15 regulatory pathway, alleviates ...
Yifei Hou, Chongzheng Yan, Xinrui Xu, Zihan Yang, Xinhui Wu, Hongxu Zhao, Xuan Song, Jianing Zhang, Yijing Li, Aohua Yang, Xiamei Lu, Yi Liu   +11 more
wiley   +1 more source