Results 51 to 60 of about 9,329 (194)

Oxylipin profile in saliva from patients with cystic fibrosis reveals a balance between pro-resolving and pro-inflammatory molecules

open access: yesScientific Reports, 2022
Oxylipins are signaling molecules originated by fatty acids that modulate vascular and bronchial tone, bronchial secretion, cytokine production and immune cell activity.
Vincenzo Carnovale   +8 more
doaj   +1 more source

Fungal and bacterial oxylipins are signals for intra- and inter-cellular communication within plant disease

open access: yesFrontiers in Plant Science, 2022
Lipids are central at various stages of host–pathogen interactions in determining virulence and modulating plant defense. Free fatty acids may act as substrates for oxidizing enzymes [e.g., lipoxygenases (LOXs) and dioxygenases (DOXs)] that synthesize ...
Marzia Beccaccioli   +8 more
doaj   +1 more source

Total Synthesis of Sacrolide A and Cytotoxic Evaluation

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
Isolated from the edible cyanobacterium Aphanothece sacrum, sacrolide A is a highly potent antimicrobial and cytotoxic metabolite. Its total synthesis via a convergent strategy enabled accurate assessment of its effects on liver and colon cells, offering new insights into its bioactivity and potential health risks.
Priyanka Kataria   +7 more
wiley   +1 more source

Western diet effects on hepatic ω6-PUFA derived oxylipins. [PDF]

open access: yes, 2019
ω6-PUFA derived oxylipins were quantified using a targeted LC/MS approach (Materials and methods). A: ω6 PUFA-derived oxylipins in RD-fed mice. B: Diet effects on ω6 PUFA-derived oxylipins. Results are presented as fold change in oxylipins induced by the
Melinda H. Spooner (6551933)   +5 more
core   +1 more source

Stability of oxylipins during plasma generation and long-term storage [PDF]

open access: yes, 2020
International audienceOxidized unsaturated fatty acids - i.e. eicosanoids and other oxylipins - are lipid mediators involved in the regulation of numerous physiological functions such as inflammation, blood coagulation, vascular tone and endothelial ...
Ostermann, Annika   +9 more
core   +1 more source

Identification of omega-3 oxylipins in human milk-derived extracellular vesicles with pro-resolutive actions in gastrointestinal inflammation

open access: yesFrontiers in Immunology, 2023
IntroductionPremature infants (PIs) are at risk of suffering necrotizing enterocolitis (NEC), and infants consuming human milk (HM) show a lower incidence than infants receiving formula.
Marta Gómez-Ferrer   +8 more
doaj   +1 more source

Soybean induced resistance to Spodoptera eridania herbivory

open access: yesPest Management Science, EarlyView.
SOD, CAT, APX, PPO, KTI, and MDA levels were higher in the resistant soybean. S. eridania herbivory increased H2O2 and MDA, but decreased SOD and PPO levels. S. eridania herbivory increased KTI activity only in the resistant variety. Isoquercitrin and daidzin were exclusive to resistant and susceptible soybeans.
Bruno Henrique Sardinha de Souza   +6 more
wiley   +1 more source

Epoxyalcohol Synthase Branch of Lipoxygenase Cascade

open access: yesCurrent Issues in Molecular Biology
Oxylipins are one of the most important classes of bioregulators, biosynthesized through the oxidative metabolism of unsaturated fatty acids in various aerobic organisms.
Yana Y. Toporkova   +2 more
doaj   +1 more source

Circadian disruption elicits sex‐specific gut microbiota, endocannabinoidome, and lipid mediator responses

open access: yesThe FEBS Journal, EarlyView.
Circadian disruption via constant light induces sex‐specific remodeling of the microbiome, lipid mediators, and immune responses. Females exhibit broader gut microbiota alterations, reduced jejunal oxylipins, increased hypothalamic N‐acylethanolamines, and a more inflammatory cytokine profile. Muscle responses are sex‐ and fiber type‐dependent: females
Pejman A. Pashaki   +7 more
wiley   +1 more source

Oxylipin Response to Acute and Chronic Exercise: A Systematic Review

open access: yesMetabolites, 2020
Oxylipins are oxidized compounds of polyunsaturated fatty acids that play important roles in the body. Recently, metabololipidomic-based studies using advanced mass spectrometry have measured the oxylipins generated during acute and chronic physical ...
Étore F. Signini   +4 more
doaj   +1 more source

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