Results 61 to 70 of about 13,219 (217)

The Emerging Parkinson's Disease Oxylipin‐Ome

Advanced Science, EarlyView.
ABSTRACT Parkinson Disease (PD) is increasingly considered a proteinopathy and lipidopathy. This proteinopathy+lipidopathy paradigm has been further refined to a fatty acid (FA)‐opathy, centering dysregulated FA metabolism as fundamental in PD lipid dysfunction.
Julia C. Kelliher, Saranna Fanning
wiley   +1 more source

Epoxyalcohol Synthase Branch of Lipoxygenase Cascade

Current Issues in Molecular Biology
Oxylipins are one of the most important classes of bioregulators, biosynthesized through the oxidative metabolism of unsaturated fatty acids in various aerobic organisms.
Yana Y. Toporkova, Elena O. Smirnova, Svetlana S. Gorina   +2 more
doaj   +1 more source

Oxylipin Response to Acute and Chronic Exercise: A Systematic Review

Metabolites, 2020
Oxylipins are oxidized compounds of polyunsaturated fatty acids that play important roles in the body. Recently, metabololipidomic-based studies using advanced mass spectrometry have measured the oxylipins generated during acute and chronic physical ...
Étore F. Signini, David C. Nieman, Claudio D. Silva, Camila A. Sakaguchi, Aparecida M. Catai   +4 more
doaj   +1 more source

Serum levels of oxylipins in achilles tendinopathy: an exploratory study. [PDF]

PLoS ONE, 2015
BACKGROUND:Linoleic acid-derived oxidation products are found in experimental pain models. However, little is known about the levels of such oxylipins in human pain.
Sandra Gouveia-Figueira, Malin L Nording, Jamie E Gaida, Sture Forsgren, Håkan Alfredson, Christopher J Fowler   +5 more
doaj   +1 more source

Selenomethionine Regulates the Arachidonic Acid Metabolism‐Ferroptosis‐Inflammation Axis to Ameliorate Colitis

Animal Research and One Health, EarlyView.
Selenomethionine can ameliorate arachidonic acid‐induced colonic injury through synergistic mechanisms, including alleviating inflammatory responses, improving barrier integrity, enhancing antioxidant capacity by upregulating selenoprotein expression, selectively regulating AA metabolism to reduce pro‐inflammatory oxylipins and promote the production ...
Huihui Tian, Longzhu Zhou, Xiaohui Feng, Jialu Shen, Xiaoping Du, Qingyu Zhao, Yuchang Qin, Junmin Zhang, Chaohua Tang   +8 more
wiley   +1 more source

Changes in bioactive lipid mediators in response to short-term exposure to ambient air particulate matter: A targeted lipidomic analysis of oxylipin signaling pathways

Environment International, 2021
Background: Exposure to ambient air particulate matter (PM) is a risk factor for cardiometabolic diseases. The knowledge of the underlying mechanisms is still evolving, but systemic inflammation and oxidative stress are central to the ability of PM to ...
Teng Wang, Yiqun Han, Haonan Li, Yanwen Wang, Tao Xue, Xi Chen, Wu Chen, Yunfei Fan, Xinghua Qiu, Jicheng Gong, Yifan Xu, Junxia Wang, Weiju Li, Tong Zhu   +13 more
doaj   +1 more source

Associated bacteria affect sexual reproduction by altering gene expression and metabolic processes in a biofilm inhabiting diatom [PDF]

, 2019
Diatoms are unicellular algae with a fundamental role in global biogeochemical cycles as major primary producers at the base of aquatic food webs. In recent years, chemical communication between diatoms and associated bacteria has emerged as a key factor
Bilcke, Gust, Cirri, Emilio, De Decker, Sam, De Veylder, Lieven, Osuna, Cristina, Pohnert, Georg, Vandepoele, Klaas, Vyverman, Wim, Werner, Markus, Werz, Oliver   +9 more
core   +2 more sources

Marine silicon for biomedical sustainability

BMEMat, EarlyView.
Schematic illustrating marine silicon for biomedical engineering. Abstract Despite momentous divergence from oceanic origin, human beings and marine organisms exhibit elemental homology through silicon utilization. Notably, silicon serves as a critical constituent in multiple biomedical processes.
Yahui Han, Zhibo Yang, Wei Xia, Chengtie Wu   +3 more
wiley   +1 more source

Stress-Induced Production of Bioactive Oxylipins in Marine Microalgae

Marine Drugs
Microalgae, stemming from a complex evolutionary lineage, possess a metabolic composition influenced by their evolutionary journey. They have the capacity to generate diverse polyunsaturated fatty acids (PUFAs), akin to those found in terrestrial plants ...
Amandyne Linares-Maurizi, Rana Awad, Anaelle Durbec, Guillaume Reversat, Valérie Gros, Jean-Marie Galano, Justine Bertrand-Michel, Thierry Durand, Rémi Pradelles, Camille Oger, Claire Vigor   +10 more
doaj   +1 more source

Acute and long-term exercise differently modulate plasma levels of oxylipins, endocannabinoids, and their analogues in young sedentary adults: A sub-study and secondary analyses from the ACTIBATE randomized controlled-trialResearch in Context

EBioMedicine, 2022
Summary: Background: Fatty acid-derived lipid mediators including oxylipins, endocannabinoids (eCBs), and their analogues, have emerged as key metabolites in the inflammatory and immune response to physiological stressors. Methods: This report was based
Lucas Jurado-Fasoli, Xinyu Di, Guillermo Sanchez-Delgado, Wei Yang, Francisco J. Osuna-Prieto, Lourdes Ortiz-Alvarez, Elke Krekels, Amy C. Harms, Thomas Hankemeier, Milena Sch..nke, Concepcion M. Aguilera, Jose M. Llamas-Elvira, Isabelle Kohler, Patrick C.N. Rensen, Jonatan R. Ruiz, Borja Martinez-Tellez   +15 more
doaj   +1 more source