Results 61 to 70 of about 10,317 (157)

The oxylipins profile and their associations with embryo quality of women with polycystic ovary syndrome: a prospective cohort study

Gynecological Endocrinology
This study was aim to investigate the oxylipins profile in the follicular fluid (FF) of women with PCOS and examine their associations with embryo quality.We conducted a targeted lipidomic study involving sixty-two cases of PCOS and age-matched controls (
Ye Tian, Fang Li, Tuo Kuang, Xiangning Li, Xin Zhou, Xiaohong Bai   +5 more
doaj   +1 more source

EPHX2 Loss Promotes CRC Migration via EET‐Dependent Chemokine Elevation and Mitochondrial Defect

Cancer Science, EarlyView.
Loss of EPHX2 promotes EET accumulation, which in turn enhances CXCL and ROS production, thereby promoting the migratory and invasive abilities of CRC cells. ABSTRACT Epoxide hydrolase 2 (EPHX2) is a key enzyme in fatty acid metabolism that metabolizes epoxyeicosatrienoic acids (EETs), lipid mediators involved in inflammation, angiogenesis, and ...
Jianjun Zhu, Jingjia Chang, Zhiyong Li, Jin Wu, Pengfei Yu, Jingjing Zheng, Li Li, Jia Tao, Hao Wu, Yintao Li, Ming Liu   +10 more
wiley   +1 more source

Effects of 6‐OHDA‐Mediated Chemical Denervation of Sympathetic Axons in Inguinal Subcutaneous White Adipose Tissue

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims White adipose tissue (WAT) innervation by sensory and sympathetic axons contributes to tissue functions, but the consequences of selectively disrupting sympathetic input to WAT remain incompletely defined. Materials and Methods We utilised 6‐hydroxydopamine (6‐OHDA) as a validated approach to achieve bilateral sympathetic denervation of ...
Gilian Gunsch, Gargi Mishra, Magdalena Blaszkiewicz, Erica de Sousa, Jake W. Willows, Katharine W. Alltop, Annemarie Towle, Shawn Collins, Andre Khalil, Isabel F. Snodgrass, Lara Agha, Kiran Prakash, Rashmika Maganuru, Sugasini Dhavamani, John W. Newman, Kristy L. Townsend   +15 more
wiley   +1 more source

Functional Significance and Implications of Phyto-Oxylipins as Potential Anti-Cancer Agents

Natural Product Communications
Objective Phyto-oxylipins are lipid molecules produced in plants by the oxidative transformation of unsaturated fatty acids via diverse metabolic pathways.
Aboagye Kwarteng Dofuor
doaj   +1 more source

Circadian disruption elicits sex‐specific gut microbiota, endocannabinoidome, and lipid mediator responses

The FEBS Journal, EarlyView.
Circadian disruption via constant light induces sex‐specific remodeling of the microbiome, lipid mediators, and immune responses. Females exhibit broader gut microbiota alterations, reduced jejunal oxylipins, increased hypothalamic N‐acylethanolamines, and a more inflammatory cytokine profile. Muscle responses are sex‐ and fiber type‐dependent: females
Pejman A. Pashaki, Timothy D. Niepokny, Tina Khalilzadehsabet, Elizabeth Dumais, Nicolas Flamand, Vincenzo Di Marzo, Eric M. Mintz, Cristoforo Silvestri   +7 more
wiley   +1 more source

Characterizing Oxylipins in Human Milk Extracellular Vesicles [PDF]

Extracellular vesicles (EVs) are non-replicating lipid bilayer membrane-bound particle formed by a parent cell and secreted into the extracellular environment.
Herrera, Priscila
core   +1 more source

Concentration of milk oxylipins after heat and homogenization treatments

Frontiers in Food Science and Technology, 2023
Heat treatment and homogenization of milk are common processing steps intended to reduce microbial load for safe human consumption, and to avoid creaming, respectively.
Caroline Thum, Caroline Thum, Caroline Thum, Amanda Cirelli, Amanda Cirelli, Yurika Otoki, Yurika Otoki, Gulustan Ozturk, Ameer Y. Taha, Warren C. McNabb, Warren C. McNabb, Nicole C. Roy, Nicole C. Roy, Nicole C. Roy, Nicole C. Roy, Juliana Maria Leite Nobrega de Moura Bell   +15 more
doaj   +1 more source

Linoleic Acid Enhances Murine Natural Killer Cell Function In Vitro but Compromises Mitochondrial Bioenergetic Function During Retroviral Infection

Immunology, EarlyView.
Natural Killer (NK) cells are potent effectors against virus‐infected and tumour cells. During Friend Virus (FV) infection, fatty acid metabolism supports NK‐cell effector functions. Here, we found that NK cells from FV‐infected mice preferentially take up linoleic acid (LA), which reduced proliferation, mitochondrial function, and increased reactive ...
Vaasudevan Sridhar, Simone Schimmer, Tanja Werner, Rachel Giesen, Mohamed Saad, Constantin P. Krempe, Sven W. Meckelmann, Ulf Dittmer, Elisabeth Littwitz‐Salomon   +8 more
wiley   +1 more source

EtOH-mediated alterations in liver oxylipins.

, 2018
A: Summary of changes in hepatic ω-6 and ω-3 PUFA-derived oxylipins in response to EtOH exposure. B: A working model wherein multiple ω-6-derived oxylipins (to the left) facilitate liver injury via distinct mechanisms.
Dennis R. Warner (5793875), Xiang Zhang (19800), Jeffrey B. Warner (5793881), Craig J. McClain (470562), Md Aminul Islam Prodhan (5793884), Ariel E. Feldstein (284627), Irina A. Kirpich (5793887), Huilin Liu (346783), Shubha Ghosh Dastidar (5793878), Xinmin Yin (284781), Russell A. Prough (4163308), Bin Gao (191656)   +11 more
core   +1 more source

Volatile organic compounds orchestrating microbiome‐mediated crop resilience: Prospects and challenges for sustainable agriculture

Journal of Integrative Plant Biology, EarlyView.
Herbivory triggers the production of green leaf volatiles, and dense planting results in induces increased concentration of linalool emission in maize canopies. These volatiles activate plant‐soil feedback that enriches beneficial rhizosphere bacteria, enhancing resistance, though sometimes at a growth cost, thereby offering new avenues for sustainable
Peiguo Yuan, Esau De la Vega‐Camarillo, Michael V. Kolomiets, Sanjay Antony‐Babu   +3 more
wiley   +1 more source