Results 81 to 90 of about 10,743 (200)

Molecular Adaptations and Sex‐Biased Regulatory Pathways in Multi‐Year Diapause of the Cabbage Beetle Colaphellus bowringi: A Duration‐Resolved Transcriptomic Analysis

Ecology and Evolution, Volume 16, Issue 11, November 2026.
This study presents the first multi‐duration, sex‐stratified transcriptomic analysis of prolonged diapause in Colaphellus bowringi, revealing that extended dormancy is maintained by coordinated metabolic suppression and sustained activation of cytoprotective pathways (e.g., glutathione metabolism, autophagy).
Lili Huang, Yan Ni, Xin Ye, Xiaona Liu, Fangsen Xue, Haimin He   +5 more
wiley   +1 more source

Macrophage-Mediated Immune Responses: From Fatty Acids to Oxylipins

, 2021
Macrophages have diverse functions in the pathogenesis, resolution, and repair of inflammatory processes. Elegant studies have elucidated the metabolomic and transcriptomic profiles of activated macrophages.
David Di Costanzo, Barbara Balestrieri, Daniel F. Dwyer   +2 more
core   +1 more source

The emerging role of oxylipins in thrombosis and diabetes [PDF]

Frontiers in Pharmacology, 2014
The prevalence of cardiovascular disease (CVD), the leading cause of death in the US, is predicted to increase due to the shift in age of the general population and increase in CVD risk factors such as obesity and diabetes. New therapies are required to decrease the prevalence of CVD risk factors (obesity and diabetes) as well as reduce ...
Tourdot, Benjamin E, Ahmed, Intekhab, Holinstat, Michael   +2 more
openaire   +3 more sources

Systems Pharmacology Investigation of Phytochemicals From Scilla peruviana L.: Integrated Gas Chromatography–Mass Spectrometry Profiling, Network Pharmacology, and Molecular Docking Reveal Potential Anti‐Inflammatory Mechanisms

ChemistryOpen, Volume 15, Issue 11, November 2026.
This study aims to characterize the volatile and fatty acid constituents of Scilla peruviana and investigate their potential anti‐inflammatory mechanisms. Volatile compounds are identified by headspace solid‐phase microextraction (HS‐SPME) coupled with GC–MS, whereas fatty acids are analyzed by GC–MS following derivatization.
Roukia Zatout, Ouided Benslama, Stefania Garzoli   +2 more
wiley   +1 more source

Oxylipins and Plant Palatability [PDF]

The Plant Cell, 2012
Oxylipins are a large family of oxygenated fatty acids that play important roles in plant development and responses to physical damage caused by herbivores, insects, and attack by pathogenic microorganisms ([Howe and Jander, 2008][1]; [Wu and Baldwin, 2010][2]).
openaire   +1 more source

Adjustment of Root System Architecture and Root Function in Response to Multifactorial Abiotic Stress

Physiologia Plantarum, Volume 178, Issue 6, November/December 2026.
ABSTRACT The root of land plants is a remarkably adaptive organ. Unlike the shoot with its main functions in light harvesting and photosynthesis, sexual reproduction and diaspore distribution, the root explores the soil for nutrient resources and water, while preferably avoiding zones of unfavorable conditions. Roots realize an extraordinarily flexible
Karl‐Josef Dietz
wiley   +1 more source

Correlation Heat Map for VLDL and whole plasma-oxylipins.

, 2014
The Pearson correlation coefficient (r) among lipoprotein-oxylipins for VLDL (A) and whole plasma oxylipins (B) is shown before treatment (top), after treatment (middle) as correlation of nM oxylipin/mM PL along with the change in oxylipins due to ...
Theresa L. Pedersen (121456), John W. Newman (121459), Verdayne R. Brandenburg (659766), Gregory C. Shearer (372998), William S. Harris (372999)   +4 more
core   +1 more source

Epoxy-oxylipins direct monocyte fate in inflammatory resolution in humans [PDF]

The role of cytochrome P450-derived epoxy-oxylipins and their metabolites in human inflammation and resolution is unknown. We report that epoxy-oxylipins are present in blood of healthy, male volunteers at baseline and following intradermal injection of ...
Trahair, H, Bishop-Bailey, D, Glanville, JRW, Gilroy, DW, Akbar, AN, Benvenutti, L, Chambers, ES, Lih, FB, Jalali, P, Feehan, KT, Evans, JG, Zeldin, DC, Motwani, M, Carvalho, JDS, De Maeyer, RPH, Edin, ML, Bracken, OV, Jamie G. Evans, Olivia V. Bracken, David Bishop-Bailey, Hugh Trahair, Trahair, Hugh, Carvalho, Jhonatan de Souza, Motwani, Madhur, Roel P. H. De Maeyer, James R. W. Glanville, Akbar, Arne N., Gilroy, Derek W., Matthew L. Edin, Fred B. Lih, Emma S. Chambers, Benvenutti, Larrissa, Madhur Motwani, Darryl C. Zeldin, Bracken, Olivia V., Evans, Jamie G., Glanville, James R. W., Parinaaz Jalali, Jhonatan de Souza Carvalho, Larrissa Benvenutti, Lih, Fred B., Arne N. Akbar, Derek W. Gilroy, Karen T. Feehan, Zeldin, Darryl C., Bishop-Bailey, David, Edin, Matthew L., De Maeyer, Roel P. H., Chambers, Emma S., Feehan, Karen T., Jalali, Parinaaz   +50 more
core   +2 more sources

Vascular Lipidomic Profiling of Potential Endogenous Fatty Acid PPAR Ligands Reveals the Coronary Artery as Major Producer of CYP450-Derived Epoxy Fatty Acids

Cells, 2020
A number of oxylipins have been described as endogenous PPAR ligands. The very short biological half-lives of oxylipins suggest roles as autocrine or paracrine signaling molecules.
Matthew L. Edin, Fred B. Lih, Bruce D. Hammock, Scott Thomson, Darryl C. Zeldin, David Bishop-Bailey   +5 more
doaj   +1 more source

Deciphering the molecular basis of maize cold tolerance via integrative regulatory network analysis

The Plant Journal, Volume 128, Issue 3, November 2026.
SUMMARY Maize (Zea mays L.) is a globally critical but cold‐sensitive crop. Understanding the temporal organization of cold‐responsive, circadian‐associated, and hormone‐associated transcriptional programs is essential for deciphering how plants balance growth and survival under cold stress to ensure food security.
Tianshuo Li, Wei Wang, Chuang Jiang, Jinkui Cheng, Fei Yi, Liusheng Duan   +5 more
wiley   +1 more source