Results 81 to 90 of about 9,329 (194)

Tracking COVID‐19 Severity and Progression Through Amines and Lipid Mediators

Journal of Medical Virology, Volume 98, Issue 7, July 2026.
ABSTRACT Coronavirus disease 2019 (COVID‐19) exhibits a broad spectrum of severity, ranging from mild to critical cases. To reduce mortality and costs, tailored early interventions for at‐risk patients are essential. This study elucidates the association between longitudinal metabolomic profiles and COVID‐19 severity and progression.
Melissa Goris, Merys Valdez, Lieke Lamont, Wei Yang, Amy Harms, Naama Karu, Sabine Bos, Jelte Geerlings, Tom Ottenhoff, Roula Tsonaka, Anna HE Roukens, M. Sesmu Arbous, Simone A. Joosten, Thomas Hankemeier, Alida Kindt, In collaboration with BEAT‐COVID group, M.S. Arbous, B.M. van den Berg, S. Cannegieter, C.M. Cobbaert, A. van der Does, J.J.M. van Dongen, J. Eikenboom, M.C.M. Feltkamp, A. Geluk, J.J. Goeman, M. Giera, T. Hankemeier, M.H.M. Heemskerk, P.S. Hiemstra, C.H. Hokke, J.J. Janse, S.P. Jochems, S.A. Joosten, M. Kikkert, L. Lamont, J. Manniën, T.H.M. Ottenhoff, M.R. del Prado, N. Queralt Rosinach, M. Roestenberg, M. Roos, A.H.E. Roukens, H.H. Smits, E.J. Snijder, F.J.T. Staal, L.A. Trouw, R. Tsonaka, A. Verhoeven, L.G. Visser, J.J.C. de Vries, D.J. van Westerloo, J. Wigbers, H.J. van der Wijk, R.C. van Wissen, M. Wuhrer, M. Yazdanbakhsh, M. Zlei   +57 more
wiley   +1 more source

LC-HRMS analysis of phospholipids bearing oxylipins [PDF]

Several oxylipins including hydroxy- and epoxy-polyunsaturated fatty acids (PUFA) act as lipid mediators. In biological samples they dominantly occur esterified in phospholipids (PL).
Nadja, Kampschulte, Luca M., Wende, Katharina M., Rund, Laura, Carpanedo, Nils Helge, Schebb   +4 more
core   +1 more source

Photooxidation of 18‐Carbon Polyunsaturated Fatty Acids to Prepare Mono‐Hydroxylated Octadecanoids

Lipids, Volume 61, Issue 4, Page 447-458, July 2026.
We developed a fast and simple one‐step synthetic strategy to produce mono‐hydroxylated metabolites based on the photosensitized oxidation of 18‐carbon polyunsaturated fatty acids (PUFAs). This approach could likely be extended to other PUFAs, suggesting that photosensitized oxidation could be employed to rapidly prepare hydroperoxides from multiple ...
Johanna Revol‐Cavalier, Mats Hamberg, Craig E. Wheelock   +2 more
wiley   +1 more source

Distribution of oxylipins in plasma compartments. [PDF]

, 2014
The distributions of oxylipins are expressed as a percent of the total baseline abundance before and after treatment. A: Oxylipins in plasma by parent fatty acid and chemistry, regardless of distribution in HDL, LDL, VLDL, or ‘free’.
Theresa L. Pedersen (121456), John W. Newman (121459), Verdayne R. Brandenburg (659766), Gregory C. Shearer (372998), William S. Harris (372999)   +4 more
core   +1 more source

Local and systemic inflammatory lipid profiling in a rat model of osteoarthritis with metabolic dysregulation. [PDF]

PLoS ONE, 2018
Bioactive oxidised lipids (oxylipins) are important signalling mediators, capable of modulating the inflammatory state of the joint and anticipated to be of importance in joint homeostasis and status of osteoarthritis.
H M de Visser, S C Mastbergen, S Ravipati, P M J Welsing, F C Pinto, F P J G Lafeber, V Chapman, D A Barrett, H Weinans   +8 more
doaj   +1 more source

Dietary Supplementation of Rumen‐Inert Fatty Acids and Rumen‐Protected Choline Modulates the Uterine Environment of Pregnant Beef Cows

Molecular Reproduction and Development, Volume 93, Issue 7, July 2026.
This graphical abstract summarizes that dietary supplementation of pregnant beef cows with unsaturated fatty acids and choline can increase (green) the concentration of metabolites in the uterine luminal fluid and alter the endometrial epithelial transcriptome during the peri‐elongation period (upregulation = green and downregulation = red).
Megan Bahr, Allyson McCarty, Zaeem Sarwar, Damon Smith, Matt Poore, Daniel Poole, Nadia Ashrafi, Romana Mimi, Stewart Graham, Ky Pohler, Jose Santos, Christian Maltecca, Felipe A. C. C. Silva   +12 more
wiley   +1 more source

Survey of volatile oxylipins and their biosynthetic precursors in bryophytes [PDF]

, 2010
Oxylipins are metabolites which are derived from the oxidative fragmentation of polyunsaturated fatty acids. These metabolites play central roles in plant hormonal regulation and defense.
Croisier, E., Rempt, Martin, Croisier, Emmanuel, Rempt, M., Pohnert, G., Pohnert, Georg   +5 more
core   +1 more source

Exploring oxylipins in processed foods: Understanding mechanisms, analytical perspectives, and enhancing quality with lipidomics

Heliyon
Oxylipins are active lipid compounds formed through the oxidation of unsaturated fatty acids. These compounds have drawn considerable attention due to the potential impact on human health and processed food quality.
Putri Widyanti Harlina, Vevi Maritha, Xiang Yang, Roy Dixon, Muchtaridi Muchtaridi, Raheel Shahzad, Ernisa Adha Nur’Isma   +6 more
doaj   +1 more source

Key metabolites secreted by Chlorella vulgaris alleviate salt stress in soybean seedlings

Journal of Integrative Plant Biology, Volume 68, Issue 7, Page 2018-2036, July 2026.
Chlorella vulgaris secretes exosome‐derived linolenic acid and inosine, which alleviate salt stress and enhance salt tolerance in soybean seedlings by activating stress‐responsive signaling networks. ABSTRACT Soil salinization is a major abiotic stress factor that reduces soybean production.
Yunyi Shi, Ruitong Chen, Kai Jiang, Aijuan Jiang, Jianchao Yang, Hongli Cui, Min Chen   +6 more
wiley   +1 more source

Development and application of methods using oxylipins to examine dietary omega-3 requirements and phospholipase A2 activity [PDF]

Oxylipins are bioactive lipid mediators formed from polyunsaturated fatty acids (PUFA) that are released from membrane phospholipids by phospholipase A2 (PLA2).
Manson, Anne
core