Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with multi-organ inflammation and defect, which is linked to many molecule mediators. Oxylipins as a class of lipid mediator have not been broadly investigated in SLE.
Jingquan He +13 more
doaj +1 more source
Role of Jasmonic Acid Pathway in Tomato Plant-Pseudomonas syringae Interaction [PDF]
The jasmonic acid pathway has been considered as the backbone of the response against necrotrophic pathogens. However, a hemi-biotrophic pathogen, such as Pseudomonas syringae, has taken advantage of the crosstalk between the different plant hormones in ...
García Agustín, Pilar +3 more
core +1 more source
Differential effects of EPA vs. DHA on postprandial vascular function and the plasma oxylipin profile in men [PDF]
Our objective was to investigate the impact of EPA versus DHA, on arterial stiffness and reactivity, and underlying mechanisms (with a focus on plasma oxylipins), in the postprandial state.
Aedin Cassidy +63 more
core +1 more source
Triacylglycerols are preferentially oxidized over free fatty acids in heated soybean oil
In oil, free fatty acids (FFAs) are thought compared the efficiency of hydrolysis wto be the preferred substrate for lipid oxidation although triacylglycerols (TAGs) are the predominant lipid class.
Qing Shen +5 more
doaj +1 more source
Intake and metabolism of omega-3 and omega-6 polyunsaturated fatty acids: nutritional implications for cardiometabolic diseases [PDF]
Prospective observational studies support the use of long-chain omega-3 polyunsaturated fatty acids (PUFAs) in the primary prevention of atherosclerotic cardiovascular disease; however, randomised controlled trials, have often reported neutral findings ...
Abdelhamid +136 more
core +1 more source
Density-Dependent Prophylaxis in Freshwater Snails Driven by Oxylipin Chemical Cues
While animal aggregations can benefit the fitness of group members, the behaviour may also lead to higher risks of parasite infection as group density increases.
Olwyn C. Friesen +7 more
doaj +1 more source
Acute Hypercapnia/Ischemia Alters the Esterification of Arachidonic Acid and Docosahexaenoic Acid Epoxide Metabolites in Rat Brain Neutral Lipids. [PDF]
In the brain, approximately 90% of oxylipins are esterified to lipids. However, the significance of this esterification process is not known. In the present study, we (1) validated an aminopropyl solid phase extraction (SPE) method for separating ...
Bazinet, Richard P +7 more
core +1 more source
Differences in oxylipin profile in psoriasis versus psoriatic arthritis
Background Oxylipins are biological lipids that have been implicated in inflammation. We previously found that certain oxylipins correlated with clinical manifestations in psoriatic arthritis (PsA) patients.
Roxana Coras +8 more
doaj +1 more source
Over the last decade oxylipins have become more recognized for their involvement in several diseases. Non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen are known to inhibit cyclooxygenase (COX) enzymes, but how NSAIDs affect oxylipins, in ...
Shuchita Tiwari +5 more
doaj +1 more source
Role of Oxylipins in the Inflammatory-Related Diseases NAFLD, Obesity, and Type 2 Diabetes
Oxygenated polyunsaturated fatty acids (oxylipins) are bioactive molecules established as important mediators during inflammation. Different classes of oxylipins have been found to have opposite effects, e.g., pro-inflammatory prostaglandins and anti ...
Mariya Misheva +2 more
doaj +1 more source

