Total oxylipin concentrations in NIST SRM 1950 plasma compared to fresh and commercially obtained human plasma [PDF]
Journal of Lipid ResearchOxylipins are oxidized PUFAs such as hydroxy-PUFAs and epoxy-PUFAs. Total oxylipins are commonly analyzed following base hydrolysis as nonesterified oxylipins by means of LC-MS/MS.
Nadja Kampschulte +5 more
doaj +2 more sources
Collection and Storage of Human Plasma for Measurement of Oxylipins [PDF]
Metabolites, 2021 Oxylipins derived from omega-3 and -6 fatty acids are actively involved in inflammatory and immune processes and play important roles in human disease.
Kristen J. Polinski +9 more
doaj +2 more sources
Predictors of oxylipins in a healthy pediatric population [PDF]
Pediatric Research, 2021 BackgroundOxylipins are formed from oxidation of omega-6 (n6) and omega-3 (n3) fatty acids (FAs). Evidence for inflammatory effects comes mostly from adults.MethodsOxylipins from n6 FA (27 n6-oxylipins) and n3 FA (12 n3-oxylipins) were measured through ...
Kathleen Waugh +23 more
core +6 more sources
Oxylipins in Aqueous Humor of Primary Open-Angle Glaucoma Patients [PDF]
BiomoleculesPurpose: Investigate the oxylipin profiles in the aqueous humor of primary open-angle glaucoma (POAG) patients. Methods: Aqueous humor samples were collected from 17 POAG patients and 15 cataract subjects and subjected to a liquid chromatography/mass ...
Jianming Xu +9 more
doaj +2 more sources
Biosynthesis of oxylipins in non-mammals [PDF]
Progress in Lipid Research, 2009 Lipid peroxidation is common to all biological systems, appearing in developmentally-regulated processes and as a response to environmental changes. Products derived from lipid peroxidation are collectively named oxylipins. Initial lipid peroxidation may
Andreou, Alexandra +2 more
core +3 more sources
Modern Methods of Sample Preparation for the Analysis of Oxylipins in Biological Samples
Molecules, 2019 Oxylipins are potent lipid mediators derived from polyunsaturated fatty acids, which play important roles in various biological processes. Being important regulators and/or markers of a wide range of normal and pathological processes, oxylipins are ...
Ivan Liakh +2 more
exaly +3 more sources
Omega-3 Fatty Acid Intake and Oxylipin Production in Response to Short-Term Ambient Air Pollution Exposure in Healthy Adults [PDF]
ToxicsOxylipins are specialized lipid mediators that can have dual functions, either promoting inflammation or supporting resolution. Exposure to air pollution is associated with systemic inflammation that may be modified by oxylipins derived from ...
Hao Chen +6 more
doaj +2 more sources
Stress-Induced Production of Bioactive Oxylipins in Marine Microalgae [PDF]
Marine DrugsMicroalgae, stemming from a complex evolutionary lineage, possess a metabolic composition influenced by their evolutionary journey. They have the capacity to generate diverse polyunsaturated fatty acids (PUFAs), akin to those found in terrestrial plants ...
Amandyne Linares-Maurizi +10 more
doaj +2 more sources
Altered polyunsaturated fatty acids and oxylipins profile in Behçet’s disease [PDF]
The Korean Journal of Internal MedicineBackground/Aims Behçet’s disease (BD) is an autoinflammatory disease of unknown etiopathogenesis. Oxylipins i.e., prostaglandins, leukotrienes, lipoxins, resolvins, and protectins are bioactive polyunsaturated fatty acids (PUFAs) derivatives involved in ...
Mohamed Kacem Ben-Fradj +6 more
doaj +3 more sources
Comprehensive Analysis of Different Subtypes of Oxylipins to Determine a LC–MS/MS Approach in Clinical Research [PDF]
MetabolitesBackground/Objectives: Different oxylipin subtypes have unique biological properties, requiring effective analytical protocols. However, establishing a complete pathway detection protocol for comprehensive oxylipin analysis is challenging.
Yurou Zhao +7 more
doaj +2 more sources