Esterified Oxylipins: Do They Matter?
Oxylipins are oxygenated metabolites of fatty acids that share several similar biochemical characteristics and functions to fatty acids including transport and trafficking.
Carmen E. Annevelink +2 more
doaj +2 more sources
Effect of cardiopulmonary bypass on plasma and erythrocytes oxylipins [PDF]
Background Oxylipins, the oxidative metabolites of polyunsaturated fatty acids (PUFAs), serve as key mediators of oxidative stress, inflammatory responses, and vasoactive reactions in vivo. Our previous work has established that hemodialysis affects both
Tong Liu +7 more
doaj +4 more sources
Collection and Storage of Human Plasma for Measurement of Oxylipins
Oxylipins derived from omega-3 and -6 fatty acids are actively involved in inflammatory and immune processes and play important roles in human disease.
Kristen J. Polinski +9 more
doaj +2 more sources
Oxylipins in Aqueous Humor of Primary Open-Angle Glaucoma Patients
Purpose: Investigate the oxylipin profiles in the aqueous humor of primary open-angle glaucoma (POAG) patients. Methods: Aqueous humor samples were collected from 17 POAG patients and 15 cataract subjects and subjected to a liquid chromatography/mass ...
Jianming Xu +9 more
doaj +2 more sources
Stress-Induced Production of Bioactive Oxylipins in Marine Microalgae
Microalgae, stemming from a complex evolutionary lineage, possess a metabolic composition influenced by their evolutionary journey. They have the capacity to generate diverse polyunsaturated fatty acids (PUFAs), akin to those found in terrestrial plants ...
Amandyne Linares-Maurizi +10 more
doaj +2 more sources
Altered polyunsaturated fatty acids and oxylipins profile in Behçet’s disease [PDF]
Background/Aims Behçet’s disease (BD) is an autoinflammatory disease of unknown etiopathogenesis. Oxylipins i.e., prostaglandins, leukotrienes, lipoxins, resolvins, and protectins are bioactive polyunsaturated fatty acids (PUFAs) derivatives involved in ...
Mohamed Kacem Ben-Fradj +6 more
doaj +3 more sources
Oxylipins-Omics Combine With Single-Molecule Analysis Identifies 13(S)-HODE Positive Extracellular Vesicles as a Diagnostic Biomarker for AFP-Negative Hepatocellular Carcinoma. [PDF]
Our work identifies EV‐derived 13(S)‐HODE as a novel biomarker for HCC, establishes a single‐molecule platform for EV lipid analysis, and constructs a high‐performance diagnostic model by integrating multi‐dimensional data, offering new potential strategies for early monitoring and precise diagnosis of HCC.2 ABSTRACT Efficient diagnostic biomarkers ...
Wang Y +15 more
europepmc +2 more sources
Oxylipins (also called eicosanoids) are enzymatically or nonenzymatically generated by oxidation of arachidonic acid (ARA) and are major mediators of ARA effects in the body.
Ningning Huang +4 more
doaj +1 more source
Effect of omega-3 fatty acid ethyl esters on the oxylipin composition of lipoproteins in hypertriglyceridemic, statin-treated subjects. [PDF]
Oxylipins mediate inflammation, vascular tension, and more. Their presence in lipoproteins could explain why lipoproteins mediate nearly identical activities.To determine how oxylipins are distributed in the lipoproteins of hypertriglyceridemic subjects,
John W Newman +4 more
doaj +1 more source
Predictors of oxylipins in a healthy pediatric population [PDF]
BackgroundOxylipins are formed from oxidation of omega-6 (n6) and omega-3 (n3) fatty acids (FAs). Evidence for inflammatory effects comes mostly from adults.MethodsOxylipins from n6 FA (27 n6-oxylipins) and n3 FA (12 n3-oxylipins) were measured through ...
Kathleen Waugh +23 more
core +1 more source

