Results 21 to 30 of about 10,317 (157)

Detoxification Cytochrome P450s (CYPs) in Families 1–3 Produce Functional Oxylipins from Polyunsaturated Fatty Acids

Cells, 2022
This manuscript reviews the CYP-mediated production of oxylipins and the current known function of these diverse set of oxylipins with emphasis on the detoxification CYPs in families 1–3.
Jazmine A. Eccles, William S. Baldwin
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Quantitative Profiling of Oxylipins in Acute Experimental Intracerebral Hemorrhage

Frontiers in Neuroscience, 2020
Oxylipins are a series of bioactive lipid metabolites derived from polyunsaturated fatty acids that are involved in cerebral homeostasis and the development of intracerebral hemorrhage (ICH).
Jun-Jie Yuan, Qiong Chen, Xiao-Yi Xiong, Qin Zhang, Qi Xie, Jia-Cheng Huang, Guo-Qiang Yang, Chang-Xiong Gong, Zhong-Ming Qiu, Hong-Fei Sang, Wen-Jie Zi, Qian He, Rui Xu, Qing-Wu Yang   +13 more
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Dietary LA and sex effects on oxylipin profiles in rat kidney, liver, and serum differ from their effects on PUFAs

Journal of Lipid Research, 2017
A vast literature on fatty acids in mammals exists, but comparable compositional data on oxylipins is lacking. Weanling Sprague-Dawley rats were therefore provided control diets or diets with higher linoleic acid (LA) or with higher LA and α-linolenic ...
Shan Leng, Tanja Winter, Harold M. Aukema   +2 more
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Absolute quantification and characterization of oxylipins in lupus nephritis and systemic lupus erythematosus

Frontiers in Immunology, 2022
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with multi-organ inflammation and defect, which is linked to many molecule mediators. Oxylipins as a class of lipid mediator have not been broadly investigated in SLE.
Jingquan He, Jingquan He, Chiyu Ma, Donge Tang, Shaoyun Zhong, Xiaofang Yuan, Fengping Zheng, Zhipeng Zeng, Yumei Chen, Dongzhou Liu, Xiaoping Hong, Weier Dai, Lianghong Yin, Yong Dai   +13 more
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Genome-wide analysis of oxylipins and oxylipin profiles in a pediatric population

Frontiers in Nutrition, 2023
BackgroundOxylipins are inflammatory biomarkers derived from omega-3 and-6 fatty acids implicated in inflammatory diseases but have not been studied in a genome-wide association study (GWAS).
Teresa Buckner, Teresa Buckner, Randi K. Johnson, Randi K. Johnson, Lauren A. Vanderlinden, Patrick M. Carry, Patrick M. Carry, Alex Romero, Suna Onengut-Gumuscu, Wei-Min Chen, Soojeong Kim, Oliver Fiehn, Brigitte I. Frohnert, Tessa Crume, Wei Perng, Katerina Kechris, Marian Rewers, Jill M. Norris   +17 more
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Triacylglycerols are preferentially oxidized over free fatty acids in heated soybean oil

npj Science of Food, 2021
In oil, free fatty acids (FFAs) are thought compared the efficiency of hydrolysis wto be the preferred substrate for lipid oxidation although triacylglycerols (TAGs) are the predominant lipid class.
Qing Shen, Zhichao Zhang, Shiva Emami, Jianchu Chen, Juliana Maria Leite Nobrega de Moura Bell, Ameer Y. Taha   +5 more
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Density-Dependent Prophylaxis in Freshwater Snails Driven by Oxylipin Chemical Cues

Frontiers in Immunology, 2022
While animal aggregations can benefit the fitness of group members, the behaviour may also lead to higher risks of parasite infection as group density increases.
Olwyn C. Friesen, Chen-Hua Li, Ellen M. E. Sykes, Jake M. Stout, Harold M. Aukema, Harold M. Aukema, Ayush Kumar, Jillian T. Detwiler   +7 more
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Differences in oxylipin profile in psoriasis versus psoriatic arthritis

Arthritis Research & Therapy, 2021
Background Oxylipins are biological lipids that have been implicated in inflammation. We previously found that certain oxylipins correlated with clinical manifestations in psoriatic arthritis (PsA) patients.
Roxana Coras, Arthur Kavanaugh, Angela Kluzniak, Dustina Holt, Amy Weilgosz, Armando Aaron, Oswald Quehenberger, Christopher Ritchlin, Monica Guma   +8 more
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Role of Oxylipins in the Inflammatory-Related Diseases NAFLD, Obesity, and Type 2 Diabetes

Metabolites, 2022
Oxygenated polyunsaturated fatty acids (oxylipins) are bioactive molecules established as important mediators during inflammation. Different classes of oxylipins have been found to have opposite effects, e.g., pro-inflammatory prostaglandins and anti ...
Mariya Misheva, Jethro Johnson, James McCullagh   +2 more
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Influence of Dietary n-3 Long Chain Polyunsaturated Fatty Acid Intake on Oxylipins in Erythrocytes of Women with Rheumatoid Arthritis

Molecules, 2023
Oxylipins derived from n-3 fatty acids are suggested as the link between these fatty acids and reduced inflammation. The aim of the present study was to explore the effect of a randomized controlled cross-over intervention on oxylipin patterns in ...
Helen M. Lindqvist, Anna Winkvist, Inger Gjertsson, Philip C. Calder, Aaron M. Armando, Oswald Quehenberger, Roxana Coras, Monica Guma   +7 more
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