Quantitative Profiling of Oxylipins in Acute Experimental Intracerebral Hemorrhage
Frontiers in Neuroscience, 2020 Oxylipins are a series of bioactive lipid metabolites derived from polyunsaturated fatty acids that are involved in cerebral homeostasis and the development of intracerebral hemorrhage (ICH).
Jun-Jie Yuan +13 more
doaj +1 more source
Temperature and time-dependent effects of delayed blood processing on oxylipin concentrations in human plasma. [PDF]
, 2019 BACKGROUND:Oxidized derivatives of polyunsaturated fatty acids, collectively known as oxylipins, are labile bioactive mediators with diverse roles in human physiology and pathology.
Gibson, Robert A +8 more
core +1 more source
Therapeutic Potential of Plant Oxylipins
International Journal of Molecular Sciences, 2022 For immobile plants, the main means of protection against adverse environmental factors is the biosynthesis of various secondary (specialized) metabolites. The extreme diversity and high biological activity of these metabolites determine the researchers’ interest in plants as a source of therapeutic agents.
Tatyana Savchenko +3 more
openaire +2 more sources
Linoleic acid participates in the response to ischemic brain injury through oxidized metabolites that regulate neurotransmission. [PDF]
, 2017 Linoleic acid (LA; 18:2 n-6), the most abundant polyunsaturated fatty acid in the US diet, is a precursor to oxidized metabolites that have unknown roles in the brain.
Bazinet, Richard P +11 more
core +1 more source
Journal of Lipid Research, 2017 A vast literature on fatty acids in mammals exists, but comparable compositional data on oxylipins is lacking. Weanling Sprague-Dawley rats were therefore provided control diets or diets with higher linoleic acid (LA) or with higher LA and α-linolenic ...
Shan Leng +2 more
doaj +1 more source
Frontiers in Immunology, 2022 Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with multi-organ inflammation and defect, which is linked to many molecule mediators. Oxylipins as a class of lipid mediator have not been broadly investigated in SLE.
Jingquan He +13 more
doaj +1 more source
Types and Distribution of Bioactive Polyunsaturated Aldehydes in a Gradient from Mesotrophic to OligotrophicWaters in the Alborán Sea (Western Mediterranean) [PDF]
, 2020 Polyunsaturated aldehydes (PUAs) are bioactive molecules suggested as chemical defenses and infochemicals. In marine coastal habitats, diatoms reach high PUA production levels during bloom episodes.
Bartual Magro, Ana +11 more
core +1 more source
The Oxylipin Pathway in Arabidopsis [PDF]
The Arabidopsis Book, 2002 Oxylipins are acyclic or cyclic oxidation products derived from the catabolism of fatty acids which regulate many defense and developmental pathways in plants. The dramatic increase in the volume of publications and reviews on these compounds since 1997 documents the increasing interest in this compound and its role in plants.
Robert A, Creelman, Rao, Mulpuri
openaire +2 more sources
Infection by a foliar endophyte elicits novel arabidopside-based plant defence reactions in its host, Cirsium arvense [PDF]
, 2014 Endophytic fungi live asymptomatically within plants. They are usually regarded as non-pathogenic or even mutualistic, but whether plants respond antagonistically to their presence remains unclear, particularly in the little-studied associations between ...
Alan C. Gange +61 more
core +1 more source
Triacylglycerols are preferentially oxidized over free fatty acids in heated soybean oil
npj Science of Food, 2021 In oil, free fatty acids (FFAs) are thought compared the efficiency of hydrolysis wto be the preferred substrate for lipid oxidation although triacylglycerols (TAGs) are the predominant lipid class.
Qing Shen +5 more
doaj +1 more source