Results 111 to 120 of about 12,681 (186)

Genetic Variations in the P2X7 Receptor: Opportunities and Challenges for Drug Development. [PDF]

Int J Mol Sci
Cheah JSY, Skarratt KK, Fuller SJ, Balle T.   +3 more
europepmc   +1 more source

P2X7 receptor antagonism with Brilliant Blue G promotes functional recovery in spontaneous canine spinal cord injury: a preliminary study in a large animal model. [PDF]

Front Neurol
Shimada Y.
europepmc   +1 more source

Expression and Functional Role of the P2X7 Receptor in Glioma Models and Tissues: A Systematic Review. [PDF]

Cancers (Basel)
Baron M, Lewandowski P, Bula B, Liberka K, Skrzypiec A, Fyrla M, Czwakiel M, Wachowicz M, Wojnicz R.   +8 more
europepmc   +1 more source

P2X7 receptor-mediated cGAS-STING pathway activation underlies chronic stress-induced depressive-like behaviors. [PDF]

Purinergic Signal
He XM, Zhang Y, Chen CY, Tang YH, Li X.
europepmc   +1 more source

Therapeutic potential of P2X7 receptor in retinal diseases. [PDF]

Purinergic Signal
Wen M, Xu Q, Xie J, Wu R, Chen X, Wen N, Huang S.   +6 more
europepmc   +1 more source

Efficacy and Safety of the Selective, Brain-Penetrant P2X7 Receptor Antagonist JNJ-55308942 (Zanvipixant) in Bipolar Depression: A Phase 2a Study. [PDF]

Biol Psychiatry Glob Open Sci
Palmer JA, Klein M, Wang D, Schmidt ME, Mazzucco C, Ionescu DF, Miller S, Li QS, Khan A, Arora A, Drevets WC.   +10 more
europepmc   +1 more source

Activity of Peptides Modulating the Action of p2x Receptors: Focus on the p2x7 Receptor. [PDF]

Pharmaceuticals (Basel)
De Souza Oliveira Carneiro JA, Teixeira GP, Rocha L, Faria RX.   +3 more
europepmc   +1 more source

A Holistic Approach to Identifying a Positron Emission Tomography (PET) Tracer Candidate for In Vivo Imaging of Purinergic P2X7 Receptor in Neuroinflammation. [PDF]

ACS Pharmacol Transl Sci
Ghafir El Idrissi I, Spinaci A, Vitone D, Intranuovo F, Niso M, Brunetti L, Francucci B, Pazarlar BA, Magnusdottir KH, Paradies E, Marobbio CMT, Ricci L, Grignolo M, Iacobazzi RM, Marucci G, Dal Ben D, Lambertucci C, Volpini R, Denora N, Adinolfi E, Mikkelsen JD, Buccioni M, Lacivita E, Leopoldo M.   +23 more
europepmc   +1 more source

Targeting the P2X7 receptor in cerebrovascular diseases: from molecular mechanisms to preclinical therapeutic potential. [PDF]

Front Pharmacol
Hu Z, Xie S, Chen C, Luo Z, Deng X, Xiao R.   +5 more
europepmc   +1 more source

Bionic Nanoparticle Hydrogel for Astrocyte-Targeted Estradiol Delivery Ameliorates Perimenopausal Depression via P2X7 Receptor Inhibition. [PDF]

Biomater Res
Chu K, Chen P, Xu W, Zhu C, Xu L, Li C, Wu F, Fan H, Zheng X, Zhou J.   +9 more
europepmc   +1 more source