Results 131 to 140 of about 15,815 (221)

P2X7 receptors and glioma cells

Purinergic Signalling, 2020
openaire   +3 more sources

Targeting the P2X7 receptor in rheumatoid arthritis: biological rationale for P2X7 antagonism

, 2014
Objectives: This paper aims to explore the functional significance of the P2X7 receptor in preclinical models of rheumatoid arthritis. Methods: Preclinical studies in vivo were performed using the rat streptococcal cell wall (SCW) arthritis model ...
McInnes, Iain B., Bowers, K., Cruwys, S., Braddock, M.   +3 more
core  

P2X7 receptor and neuroinflammation in neurodegenerative disorders: an autoradiography study with [ 18 F]JNJ-64413739. [PDF]

Nucl Med Commun
Ashok AH, Field S, Ramakrishnan NK, Thompson S, O'Brien JT, Aigbirhio FI.   +5 more
europepmc   +1 more source

Modeling the P2X7 receptor: a comparative analysis of conventional methods and AlphaFold. [PDF]

Front Pharmacol
Lima LM, Ferreira NCDS, Alves LA.
europepmc   +1 more source

P2X7 receptor and its splice variants in osteosarcoma

, 2014
To P2X7 receptor a role in bone formation and resorption has been assigned since the first studies on receptor knock out mice. Both osteoblast proliferation and osteoclast activation and fusion have been demonstrated to be related to P2X7 receptor. These
ADINOLFI, Elena, DI VIRGILIO, Francesco, T. Ricco, D. Colognesi, A. Gartland, GIULIANI, Anna Lisa, CAPECE, Marina, C. Roncato, Q. G. Wang   +8 more
core  

P2X7 receptor: An emerging therapeutic target in acute myeloid leukemia (Review). [PDF]

Int J Oncol
Liu Y, Xue H, Mai H, Sang T, Li Z, Wang N, Feng L.   +6 more
europepmc   +1 more source

P2X7 receptor mediates the anti-tumor effect of running on cervical cancer in mice. [PDF]

Purinergic Signal
Xiong HY, Li R, Hu XM, Zhang Y, Rubini P, Illes P, Tang Y.   +6 more
europepmc   +1 more source

Extracellular ATP induces the proinflammatory phenotype transition of MH7A cells by activating P2X7 receptor. [PDF]

Purinergic Signal
Wang C, Hao J, Liu Y, Shen H.
europepmc   +1 more source

Insight on P2X7 receptor role as oncogene

, 2014
Activation of P2X7 receptor is impacting almost all recognized cancer hallmarks [Hanahan D, Weinberg RA. Cell. 2011;144(5):646–674] including sustained proliferation [Baricordi OR, Melchiorri L, Adinolfi E, Falzoni S, Chiozzi P, Buell G, Di Virgilio F. J
ADINOLFI, Elena, FRANCESCHINI, Alessia, DI VIRGILIO, Francesco, GIULIANI, Anna Lisa, CAPECE, Marina, A. Rotondo, AMOROSO, Francesca Saveria   +6 more
core  

The P2X7 Receptor Promotes Intestinal Fibrosis by Modulating the Gut Microbiota and the Inflammasome. [PDF]

Cell Mol Gastroenterol Hepatol
Ribeiro BE, de Lima IS, da Silva E Souza KC, Rosas SLB, Santana PT, Amaral G, Machado JC, de Oliveira RP, Leal C, Thompson C, Thompson F, Castelo-Branco MTL, Coutinho-Silva R, de Souza HSP.   +13 more
europepmc   +1 more source