Results 81 to 90 of about 12,246 (181)
Frontiers in Psychiatry, 2019 Diabetic neuropathic pain (DNP) and major depressive disorder (MDD) are common complications of diabetes mellitus and mutually affect each other. As a member of the ATP-gated ion channel family, P2X7 receptor is associated with the transduction of pain ...
Shu Guan +10 more
doaj +1 more source
PLoS ONE, 2013 The P2X7 receptor regulates cell growth through mediation of apoptosis. Low level expression of P2X7 has been linked to cancer development because tumor cells harboring a defective P2X7 mechanism can escape P2X7 pro-apoptotic control.
Songyin Huang +9 more
doaj +1 more source
P2X7 receptor antagonism in amyotrophic lateral sclerosis
Neural Regeneration Research, 2017 Amyotrophic lateral sclerosis (ALS) is a rapidly progressive disorder characterized by the degeneration and subsequent loss of upper and lower motor neurons, resulting in reduced muscle function and paralysis (Mathis et al., 2017). Current therapies are limited to the oral administration of riluzole, which improves survival by only 3 months (Mathis et ...
Sluyter, Ronald +3 more
openaire +4 more sources
Scientific ReportsP2X7 receptors mediate immune and endothelial cell responses to extracellular ATP. Acute pharmacological blockade increases renal blood flow and filtration rate, suggesting that receptor activation promotes tonic vasoconstriction.
Josselin Nespoux +9 more
doaj +1 more source
Editorial: P2X7 Receptor Function in Neurodegenerative Diseases [PDF]
Frontiers in Cellular Neuroscience, 2021 Robson Xavier Faria +2 more
openaire +3 more sources
Point Mutations of P2X7 Receptors [PDF]
Biophysical Journal, 2020 Hannah Dentler +3 more
openaire +1 more source
Chagas disease, COVID‐19 and P2X7 receptor [PDF]
Scandinavian Journal of Immunology, 2022 Caroline de Souza Ferreira Pereira +1 more
openaire +2 more sources