Results 21 to 30 of about 76,399 (242)

p35 regulates the CRM1-dependent nucleocytoplasmic shuttling of nuclear hormone receptor coregulator-interacting factor 1 (NIF-1).

open access: yesPLoS ONE, 2014
Cyclin-dependent kinase 5 (Cdk5) is a proline-directed serine/threonine kinase, which plays critical roles in a wide spectrum of neuronal functions including neuronal survival, neurite outgrowth, and synapse development and plasticity.
Xiao-Su Zhao   +5 more
doaj   +1 more source

An improved luciferase immunosorbent assay for ultrasensitive detection of antibodies against African swine fever virus

open access: yesFrontiers in Microbiology, 2022
African swine fever (ASF), caused by African swine fever virus (ASFV), is a fatal infectious disease of pigs and causes great socioeconomic losses globally. The reliable diagnostic method is critical for prevention and control of the disease.
Qiongjie Wang   +10 more
doaj   +1 more source

Biological functions of CDK5 and potential CDK5 targeted clinical treatments. [PDF]

open access: yes, 2017
Cyclin dependent kinases are proline-directed serine/threonine protein kinases that are traditionally activated upon association with a regulatory subunit.
Casimiro, Mathew C.   +2 more
core   +2 more sources

Mild Traumatic Brain Injury in Adolescent Mice Alters Skull Bone Properties to Influence a Subsequent Brain Impact at Adulthood: A Pilot Study

open access: yesFrontiers in Neurology, 2018
Mild traumatic brain injuries (mTBI) are common during adolescence, and limited clinical evidence suggests that a younger age at first exposure to a mTBI may lead to worse long-term outcomes.
Thomas J. McColl   +13 more
doaj   +1 more source

On the Observability of "Invisible" / "Nearly Invisible" Charginos [PDF]

open access: yes, 1998
It is shown that if the charginos decay into very soft leptons or hadrons + $\not{E}$ due to degeneracy/ near- degeneracy with the LSP or the sneutrino, the observability of the recently proposed signal via the single photon (+ soft particles) + $\not{E}$
A. Brignole   +26 more
core   +3 more sources

Paragangliome retropéritonéal: à propos d'un cas et revue de littérature

open access: yesThe Pan African Medical Journal, 2015
Les paragangliomes rétropéritonéaux non fonctionnels sont des tumeurs rares. Ils sont définis comme des tumeurs chromaffines extra- surrénaliennes et représentent environ 1/5ème des tumeurs chromaffines.
Yassine Fahmi   +8 more
doaj   +1 more source

Expression of the Baculovirus p35 Protein in Tobacco Affects Cell Death Progression and Compromises N Gene-Mediated Disease Resistance Response to Tobacco mosaic virus

open access: yesMolecular Plant-Microbe Interactions, 2003
The p35 protein from baculovirus is a broad-range caspase inhibitor and suppresses programmed cell death in animals. We report here the effects of transgenic expression in tobacco of the p35 protein during the hypersensitive response (HR).
Olga del Pozo, Eric Lam
doaj   +1 more source

Peroxisome proliferator-activated receptor delta limits the expansion of pathogenic Th cells during central nervous system autoimmunity. [PDF]

open access: yes, 2010
Peroxisome proliferator-activated receptors (PPARs; PPAR-alpha, PPAR-delta, and PPAR-gamma) comprise a family of nuclear receptors that sense fatty acid levels and translate this information into altered gene transcription.
Axtell, Robert   +11 more
core   +3 more sources

Crosstalk between Cdk5/p35 and ERK1/2 signalling mediates spinal astrocyte activity via the PPARγ pathway in a rat model of chronic constriction injury

open access: yesJournal of Neurochemistry, 2019
The specific mechanisms underlying cyclin‐dependent kinase 5 (Cdk5)‐mediated neuropathic pain at the spinal cord level remain elusive. The aim of the present study was to explore the role of crosstalk between Cdk5/p35 and extracellular signal‐regulated ...
Yuling Zhong   +5 more
semanticscholar   +1 more source

Hepatic fascioliasis presenting with bile duct obstruction: a case report

open access: yesThe Pan African Medical Journal, 2017
Fascioliasis is a zoonotic infection caused by a liver trematode: fasciola hepatica; which commonly affects cattle and sheep, humans are accidental hosts. Several cases have been reported in the literature worldwide with a large geographical distribution.
Rachid Lefriyekh   +10 more
doaj   +1 more source

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