Results 51 to 60 of about 76,399 (242)
Neurobiology of Disease, 2003 Neuronal excitotoxicity causes energetic impairment and the ensuing cell death has historically been regarded as necrotic. Recent findings, however, indicate that apoptosis may participate in excitotoxicity.
Madhuri Roy, Robert M Sapolsky
doaj +1 more source
Expression of baculovirus P35 prevents cell death in Drosophila [PDF]
, 1994 The baculovirus P35 protein functions to prevent apoptotic death of infected cells. We have expressed P35 in the developing embryo and eye of the fly Drosophila melanogaster. P35 eliminates most, if not all, normally occurring cell death in these tissues,
Hay, Bruce A. +2 more
core
Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon +12 more
wiley +1 more source
Whole‐Body Pattern of Muscle Degeneration and Progression in Sarcoglycanopathies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterize whole‐body intramuscular fat distribution pattern in patients with sarcoglycanopathies and explore correlations with disease severity, duration and age at onset. Methods Retrospective, cross‐sectional, multicentric study enrolling patients with variants in one of the four sarcoglycan genes who underwent whole‐body ...
Laura Costa‐Comellas +39 more
wiley +1 more source
Cyclin Dependent Kinase 5 in Endothelial Cell Migration [PDF]
, 2010 Cyclin dependent kinase 5 (Cdk5) is studied to take part in the migration neurons and development of brain. It is proven to participate also in the mediation of endothelial cell migration and angiogenesis.
Heiskanen, Suvi
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Biometric responses to music-rich segments in films: the CDVPlex [PDF]
, 2009 Summarising or generating trailers for films or movies involves finding the highlights within those films, those segments where we become most afraid, happy, sad, annoyed, excited, etc.
Rothwell, Sandra, Smeaton, Alan F.
core +2 more sources
Ocular expression of cyclin‐dependent kinase 5 in patients with proliferative diabetic retinopathy
Journal of Diabetes Investigation, 2022 Aims/Introduction Inhibition of peroxisome proliferator‐activated receptor gamma (PPARγ) phosphorylation mediated by cyclin‐dependent kinase 5 (Cdk5) is one of the main mechanisms of action of antidiabetic drugs.
Hiroki Sano +6 more
doaj +1 more source
Normal forms for Kummer surfaces
, 2019 We determine normal forms for the Kummer surfaces associated with abelian surfaces of polarization of type $(1,1)$, $(1,2)$, $(2,2)$, $(2,4)$, and $(1,4)$.
Clingher, Adrian, Malmendier, Andreas
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Backbone Heterojunction Photocatalysts for Efficient Sacrificial Hydrogen Production
Advanced Functional Materials, EarlyView.Herein, a ‘single‐component’ organic semiconductor photocatalyst is presented in which a molecular donor is bonded to a polymer acceptor. The resultant material demonstrates exceptional photocatalytic activity for hydrogen evolution in aqueous triethylamine with an outstanding external quantum efficiency of 38% at 420 nm.
Richard J. Lyons +11 more
wiley +1 more source
Advanced Science, EarlyView.The ultra‐short‐acting sedative remimazolam has a sustained therapeutic effect on the core symptoms of VPA‐exposed mice. Remimazolam, a GABA agonist, exerts its therapeutic effects by protecting dopamine neurons in the VTA of VPA‐exposed mice. Meanwhile, ferroptosis is the critical mechanism by which remimazolam protects VTA dopaminergic neurons and ...
Yuxin Zhang +7 more
wiley +1 more source