Results 41 to 50 of about 8,365 (192)
Frontiers in Microbiology, 2022 The stringent response mediated by the signal molecule (p)ppGpp is involved in response to multiple environmental stresses and control of various physiological processes.
Wen-Liang Yin +29 more
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Possible Roles for Basal Levels of (p)ppGpp: Growth Efficiency Vs. Surviving Stress
Frontiers in Microbiology, 2020 Two (p)ppGpp nucleotide analogs, sometimes abbreviated simply as ppGpp, are widespread in bacteria and plants. Their name alarmone reflects a view of their function as intracellular hormone-like protective alarms that can increase a 100-fold when sensing
Llorenç Fernández-Coll, Michael Cashel
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Transcription regulation of the Escherichia coli pcnB gene coding for poly(A) polymerase I: roles of ppGpp, DksA and sigma factors [PDF]
, 2010 Poly(A) polymerase I (PAP I), encoded by the pcnB gene, is a major enzyme responsible for RNA polyadenylation in Escherichia coli, a process involved in the global control of gene expression in this bacterium through inXuencing the rate of transcript ...
Grzegorz Węgrzyn +11 more
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Role of RelA and SpoT in Burkholderia pseudomallei Virulence and Immunity [PDF]
, 2012 Burkholderia pseudomallei is a Gram-negative soil bacterium and the causative agent of melioidosis, a disease of humans and animals. It is also listed as a category B bioterrorism threat agent by the U.S.
Wand, ME +11 more
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Data_Sheet_1_Dynamic Metabolic Response to (p)ppGpp Accumulation in Pseudomonas putida.PDF
, 2022 The stringent response is a ubiquitous bacterial reaction triggered by nutrient deprivation and mediated by the intracellular concentrations of ppGpp and pppGpp.
Fabien Létisse (424703) +1 more
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Microbial Cell, 2023 The bacterial stringent response and its effector alarmone guanosine penta- or tetra – phosphates (p)ppGpp are vital for bacterial tolerance and survival of various stresses in environments (including antibiotics) and host cells (viru-lence).
Paulina Katarzyna Grucela +4 more
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(p)ppGpp and the bacterial cell cycle
Journal of Biosciences, 2016 Genes of the Rel/Spo homolog (RSH) superfamily synthesize and/or hydrolyse the modified nucleotides pppGpp/ ppGpp (collectively referred to as (p)ppGpp) and are prevalent across diverse bacteria and in plant chloroplasts. Bacteria accumulate (p)ppGpp in response to nutrient deprivation (generically called the stringent response) and elicit appropriate ...
Aanisa, Nazir, Rajendran, Harinarayanan
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Data_Sheet_2_Dynamic Metabolic Response to (p)ppGpp Accumulation in Pseudomonas putida.xlsx
, 2022 The stringent response is a ubiquitous bacterial reaction triggered by nutrient deprivation and mediated by the intracellular concentrations of ppGpp and pppGpp.
Fabien Létisse (424703) +1 more
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eLife, 2019 The alarmone (p)ppGpp regulates diverse targets, yet its target specificity and evolution remain poorly understood. Here, we elucidate the mechanism by which basal (p)ppGpp inhibits the purine salvage enzyme HPRT by sharing a conserved motif with its ...
Brent W Anderson +7 more
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Action of the bacterial alarmones (p)ppGpp on translational GTPases
, 2022 Ribosomes are intricate and highly complex macromolecular structures. Their maturation into fully functional entities is aided by a vast number of accessory proteins, many of which belong to the class of GTPases. GTPases do furthermore play pivotal roles
Majkini, Mohamad
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