Results 171 to 180 of about 109,341 (200)

Inhibition of KDEL Receptors Remodels the Tumor Microenvironment for T Cell Independent Tumor Regression

Advanced Science, EarlyView.
Inhibition of KDELR2 in a small fraction of tumor cells generates sustainable immunogenic cell death conditions within the tumor microenvironment. These conditions promote the regression of tumors in a T cell independent manner. During regression, macrophages prime T cells that subsequently provide systemic protection against recurrence. The potency of
Shakti P Pattanayak, Hong Wang, Belinda Willard, Timothy A. Chan, William C Merrick, Zheng‐Rong Lu, Boaz Tirosh   +6 more
wiley   +1 more source

IgG and IgM responses to PfEMP1 domains associated with semi-immunity to clinical malaria in Burkinabe children under five. [PDF]

Front Immunol
Dankyi BO, Yuguchi T, Rojrung R, Nagaoka H, Kanoi BN, Tiono AB, Nebie I, Ouedraogo A, Tanaka K, Miyake Y, Miura K, Sattabongkot J, Sirima SB, Tsuboi T, Takashima E.   +14 more
europepmc   +1 more source

Targeting a Myeloid–Regulatory B Cell Network Reverses Immune Paralysis in Periprosthetic Joint Infections

Advanced Science, EarlyView.
Periprosthetic joint infection establishes a sophisticated immunosuppressive network between CXCR4+ PMN‐MDSCs and Bregs, inducing profound CD8+ T cell paralysis. Alendronate effectively disrupts this CXCR4+ PMN‐MDSC–Breg axis by targeting STAT3, thereby restoring local immune surveillance.
Jintao Wu, Shutao Zhang, Yumin Lin, Juyang Jiao, Zhiwei Fu, Qimin Hong, Ziyi Zhao, Xinhua Qu, Fei Su, Bing Yue   +9 more
wiley   +1 more source

Pigs lacking Natural Killer T cells have altered cellular responses to influenza. [PDF]

PLoS Pathog
Kwon T, Gu W, Morozov I, Carossino M, Lyoo EL, McDowell CD, Li Y, Balasuriya UBR, Huang Y, Madrid DMC, Lee K, Richt JA, Driver JP.   +12 more
europepmc   +1 more source

Skin-Colored Nodular Facial Swelling in a Middle-Aged Female. [PDF]

Indian Dermatol Online J
Sharma A, Chatterjee D, Vinay K.
europepmc   +1 more source

A paired sequence language model for protein-protein interaction modeling. [PDF]

Nat Commun
Liu J, Chen H, Zhang Y.
europepmc   +1 more source

Case Report: A case of ovarian carcinoma manifesting with chest tightness as the initial clinical presentation accompanied by marked elevation of pleural effusion amylase levels. [PDF]

Front Oncol
Ou GY, Zhu YC, Li K, Li CJ, Yi X, Wan QB, Shen HL.   +6 more
europepmc   +1 more source

Inhibitory Circuits Can Restore OFF Pathway Responses in Retinal Prostheses. [PDF]

J Neurosci
Carleton M, Oesch NW.
europepmc   +1 more source

Seasonal vaccine-induced immunity shows preserved cross-reactivity to H3N2 subclade K in adults. [PDF]

EBioMedicine
Wilson A, Lerman B, Ramsamooj R, Mischka J, Ehrenhaus J, Aracena A, Figueroa Y, Farrugia K, Gonzalez-Reiche AS, Nardulli J, Khalil Z, Gleason C, Hermann E, Srivastava K, Sordillo EM, van Bakel H, Abbad A, Krammer F, Simon V.   +18 more
europepmc   +1 more source