Results 21 to 30 of about 92,701 (241)
Indian Journal of Animal Sciences, 2023 This study aimed to determine the optimum timing of embryonic thermal manipulation (TM) that may result in improvement of mRNA expression of myogenic upstream activation factors viz.
ABDELHAFEED DALAB +4 more
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The regenerative potential of Pax3/Pax7 on skeletal muscle injury
Journal of Genetic Engineering and Biotechnology, 2022 Background Skeletal muscle mishaps are the most well-known incidents in society, especially among athletes and the military population. From the various urgency, this accident needs to be cured more quickly.
Muhamad Azhar +2 more
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The transcription factor paired box-5 promotes osteoblastogenesis through direct induction of Osterix and Osteocalcin [PDF]
Journal of Bone and Mineral Research, 2012 Abstract Although skeletal abnormalities are seen in mice deficient of particular paired box (Pax) family proteins, little attention has been paid to their role in osteoblastogenesis so far. Here, we investigated the possible involvement of several Pax family members in mechanisms underlying the regulation of differentiation and ...
Eiichi, Hinoi +8 more
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ROLE OF PAX-5 TRANSCRIPTION FACTOR IN PATHOGENESIS OF BRONCHIAL ASTHMA
Медицинская иммунология, 2014 . Expression characteristics of transcription factor PAX-5 (paired box 5) are considered for different clinical variants of bronchial asthma (BA). Low levels of PAX-5 expression may be a reason for progression into a severe allergic asthma, whereas ...
V. N. Mineev +4 more
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Pax7 is necessary and sufficient for the myogenic specification of CD45+:Sca1+ stem cells from injured muscle. [PDF]
PLoS Biology, 2004 CD45(+):Sca1(+) adult stem cells isolated from uninjured muscle do not display any myogenic potential, whereas those isolated from regenerating muscle give rise to myoblasts expressing the paired-box transcription factor Pax7 and the bHLH factors Myf5 ...
Patrick Seale +3 more
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The DNA binding activity of the paired box transcription factor Pax‐3 is rapidly downregulated during neuronal cell differentiation [PDF]
FEBS Letters, 1998 Mutations in the murine Pax‐3 gene lead to a range of developmental abnormalities including deficiencies in sensory and sympathetic neurones. We have investigated Pax‐3 expression during neuronal differentiation and show levels of Pax‐3 DNA binding decrease upon cell cycle arrest and morphological differentiation.
Reeves, F.C +3 more
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PLoS Biology, 2019 The transcriptional mechanisms driving lineage specification during development are still largely unknown, as the interplay of multiple transcription factors makes it difficult to dissect these molecular events.
Alessandro Magli +12 more
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Cells, 2020 Satellite cells (SCs) participate in skeletal muscle plasticity/regeneration. Activation of SCs implies that nuclear changes underpin a new functional status.
Manuela Malatesta +3 more
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Identification of rare paired box 3 variant in strabismus by whole exome sequencing [PDF]
International Journal of Ophthalmology, 2017 AIM: To identify the potentially pathogenic gene variants that contributes to the etiology of strabismus. METHODS: A Chinese pedigree with strabismus was collected and the exomes of two affected individuals were sequenced using the next-generation ...
Hui-Min Gong +5 more
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Neural Regeneration Research, 2023 Neural progenitor cells (NPCs) capable of self-renewal and differentiation into neural cell lineages offer broad prospects for cell therapy for neurodegenerative diseases.
Yu Guo +9 more
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