Palmitoylation landscapes across human cancers reveal a role of palmitoylation in tumorigenesis
Journal of Translational Medicine, 2023 Background Protein palmitoylation, which is catalyzed by palmitoyl-transferase and de-palmitoyl-transferase, plays a crucial role in various biological processes. However, the landscape and dynamics of protein palmitoylation in human cancers are not well
Yue Kong +8 more
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Diverse Roles of Protein Palmitoylation in Cancer Progression, Immunity, Stemness, and Beyond
Cells, 2023 Protein S-palmitoylation, a type of post-translational modification, refers to the reversible process of attachment of a fatty acyl chain—a 16-carbon palmitate acid—to the specific cysteine residues on target proteins.
Mingli Li, Leisi Zhang, Chun-Wei Chen
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Protein palmitoylation: an emerging regulator of inflammatory signaling and diseases [PDF]
Frontiers in ImmunologyProtein palmitoylation is a reversible lipid modification in which palmitoyl esters are covalently attached to cysteine residues of proteins. It controls various cellular physiological processes and alters protein stability, conformation, localization ...
Rong Chen +6 more
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Recent advances in S-palmitoylation and its emerging roles in human diseases [PDF]
Journal of Hematology & OncologyS-palmitoylation, one reversible post-translational modification (PTM) involving the binding of palmitate to proteins, influences protein stability, localization and interactions.
Juanjuan Shang +2 more
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Protein palmitoylation in cancer: molecular functions and therapeutic potential
Molecular Oncology, 2023 Protein S‐palmitoylation (hereinafter referred to as protein palmitoylation) is a reversible lipid posttranslational modification catalyzed by the zinc finger DHHC‐type containing (ZDHHC) protein family.
Binhui Zhou +3 more
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Protein S-palmitoylation modification: implications in tumor and tumor immune microenvironment
Frontiers in ImmunologyProtein S-palmitoylation is a reversible post-translational lipid modification that involves the addition of a 16-carbon palmitoyl group to a protein cysteine residue via a thioester linkage.
Yijiao Chen, Yongsheng Li, Lei Wu
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S-Palmitoylation of Synaptic Proteins in Neuronal Plasticity in Normal and Pathological Brains
Cells, 2023 Protein lipidation is a common post-translational modification of proteins that plays an important role in human physiology and pathology. One form of protein lipidation, S-palmitoylation, involves the addition of a 16-carbon fatty acid (palmitate) onto ...
Anna Buszka +4 more
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Palmitoylation in cancer: decoding its roles in signal transduction, tumor immunity, and emerging therapeutic opportunities [PDF]
Frontiers in ImmunologyPalmitoylation, a reversible post-translational modification involving the attachment of palmitic acid to cysteine residues of proteins, plays a critical role in the regulation of protein localization, stability, and function.
Qiguang Lu +4 more
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Post-translational palmitoylation of metabolic proteins
Frontiers in Physiology, 2023 Numerous cellular proteins are post-translationally modified by addition of a lipid group to their structure, which dynamically influences the proteome by increasing hydrophobicity of proteins often impacting protein conformation, localization, stability,
Kaitlyn M. J. H. Dennis, Lisa C. Heather
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Context-dependent roles of palmitoylation in acute respiratory distress syndrome: integrating inflammation, cell death and repair [PDF]
European Respiratory ReviewAcute respiratory distress syndrome (ARDS) is a life-threatening condition characterised by dysregulated inflammation, immune imbalance and impaired alveolar repair.
Qimin Ma, Yusong Wang, Feng Zhu
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