Results 1 to 10 of about 13,061 (210)
Selective Cellular Uptake and Druggability Efficacy through Functionalized Chitosan-Conjugated Polyamidoamine (PAMAM) Dendrimers [PDF]
SensorsNanotechnology has ushered in significant advancements in drug design, revolutionizing the prevention, diagnosis, and treatment of various diseases. The strategic utilization of nanotechnology to enhance drug loading, delivery, and release has garnered ...
Ye Hu, Jian Chen, Wenyan Hu
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Curcumin encapsulated in PAMAM dendrimers for the therapeutic treatment of ischemic stroke in rats [PDF]
Frontiers in Cell and Developmental BiologyIntroductionIschemic stroke is a devastating neurovascular condition that occurs when cerebral tissue fails to receive an adequate supply of oxygen. Despite being a leading cause of death and disability worldwide, therapeutic interventions are currently ...
Justin Stadler +25 more
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Combination of Drug Delivery Properties of PAMAM Dendrimers and Cytotoxicity of Platinum(IV) Complexes—A More Selective Anticancer Treatment? [PDF]
Pharmaceutics, 2023 Based on their drug delivery properties and activity against tumors, we combined PAMAM dendrimers with various platinum(IV) complexes in order to provide an improved approach of anticancer treatment.
Yvonne Lerchbammer-Kreith +6 more
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Intrinsic Fluorescence of PAMAM Dendrimers-Quenching Studies. [PDF]
Polymers (Basel), 2018 Intrinsic, non-traditional fluorescence of polyamidoamine (PAMAM) dendrimers that do not possess classical fluorophores has been attracting considerable interest for the last decade. Many hypotheses regarding the source of the fluorescence have appeared, but some of them are still disputable.
Konopka M +2 more
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From Structure to Function: The Promise of PAMAM Dendrimers in Biomedical Applications [PDF]
PharmaceuticsPAMAM dendrimers are distinguished by their capacity for functionalization, which enhances the properties of the compounds they transport, rendering them highly versatile nanoparticles with extensive applications in the biomedical domain, including drug,
Said Alamos-Musre +9 more
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Conjugation of Gentamicin to Polyamidoamine Dendrimers Improved Anti-bacterial Properties against Pseudomonas aeruginosa [PDF]
Advanced Pharmaceutical Bulletin, 2021 Purpose: This study aimed to design gentamicin-conjugated poly (amidoamine) (PAMAM) dendrimers to increase the therapeutic efficiency of gentamicin against Pseudomonas aeruginosa.
Hamed Sheykhloo +4 more
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High Fluorescent Porphyrin-PAMAM-Fluorene Dendrimers [PDF]
Molecules, 2015 Two new classes of dendrimers bearing 8 and 32 fluorene donor groups have been synthesized. The first and second generations of these porphyrin-PAMAM-fluorene dendrimers were characterized by 1H-NMR, 13C-NMR, FTIR, UV-vis spectroscopy, elemental analyses and MALDI-TOF mass spectrometry.
Garfias-Gonzalez, Karla +6 more
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Pharmaceutics, 2022 A convenient method for the synthesis of the second generation of PAMAM dendrimers based on a p-tert-butylthiacalix[4]arene core in cone, partial cone and 1,3-alternate conformations was developed.
Olga Mostovaya +7 more
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Inverse Polyamidoamine (i‐PAMAM) Dendrimer Antimicrobials
Helvetica Chimica Acta, 2023 AbstractHere we redesigned the branches of polyamidoamine (PAMAM) dendrimers by moving the amide carbonyl group on the other side of the amide nitrogen atom, transforming the β‐alaninyl‐amidoethylamine branch, which easily undergoes retro‐Michael reactions and renders PAMAMs intrinsically unstable, into a more stable glycyl‐amidopropylamine branch. The
Bonvin, Etienne, Reymond, Jean-Louis
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Materials & Design, 2022 Fluorescent non-conjugated polymers without any π-aromatic building blocks are of great significance in biological applications due to low cytotoxicity and good biocompatibility.
Xiao-lin Guan +9 more
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