Results 101 to 110 of about 13,061 (210)

PAMAM-Calix-Dendrimers: Third Generation Synthesis and Impact of Generation and Macrocyclic Core Conformation on Hemotoxicity and Calf Thymus DNA Binding

Pharmaceutics
Background/Objectives: Current promising treatments for many diseases are based on the use of therapeutic nucleic acids, including DNA. However, the list of nanocarriers is limited due to their low biocompatibility, high cost, and toxicity. The design of
Olga Mostovaya, Igor Shiabiev, Daniil Ovchinnikov, Dmitry Pysin, Timur Mukhametzyanov, Alesia Stanavaya, Viktar Abashkin, Dzmitry Shcharbin, Arthur Khannanov, Marianna Kutyreva, Mingwu Shen, Xiangyang Shi, Pavel Padnya, Ivan Stoikov   +13 more
doaj   +1 more source

Fluorescent Polymeric Materials for Bacterial Interaction and Detection

Macromolecular Chemistry and Physics, Volume 227, Issue 3, 16 February 2026.
This review highlights recent advances in fluorescent polymer design for bacterial interaction and detection. It examines key classes of functional polymers—including conjugated, glycopolymeric, and pH‐responsive systems—and the mechanisms they employ for bacterial recognition. Emphasis is placed on molecular design strategies that enhance selectivity,
Dilani Chathumalee, Stephen J. Butler, Amanda K. Pearce   +2 more
wiley   +1 more source

Recent Research Progress on Polyamidoamine-Engineered Hydrogels for Biomedical Applications

Biomolecules
Hydrogels are three-dimensional crosslinked functional materials with water-absorbing and swelling properties. Many hydrogels can store a variety of small functional molecules to structurally and functionally mimic the natural extracellular matrix; hence,
Li Liu, Zhiling Li, Baiyan Yang, Xiaoqing Jia, Shige Wang   +4 more
doaj   +1 more source

Polyamidoamine Dendrimer Conjugates with Cyclodextrins as Novel Carriers for DNA, shRNA and siRNA

Pharmaceutics, 2012
Gene, short hairpin RNA (shRNA) and small interfering RNA (siRNA) delivery can be particularly used for the treatment of diseases by the entry of genetic materials mammalian cells either to express new proteins or to suppress the expression of proteins ...
Hidetoshi Arima, Keiichi Motoyama, Taishi Higashi   +2 more
doaj   +1 more source

Synthesis of microporous silica nanoparticles to study water phase transitions by vibrational spectroscopy [PDF]

, 2019
Silica can take many forms, and its interaction with water can change dramatically at the interface. Silica based systems offer a rich tapestry to probe the confinement of water as size and volume can be controlled by various templating strategies and ...
Arriagada, Asay, Bechtel, Boreyko, Cerveny, Djojoputro, Dou, Enthaler, Fang, Fayer, Fumagalli, Huang, Jacobs, Joo, Knight, Kostko, Le Caër, Lee, Lin, Lin, Lin, Liu, Mei, Musat, Nagarajan, Nagata, Noy, Ostroverkhov, Peixinho, Peng, Qiao, Ren, Rosu-Finsen, Sharma, Sulpizi, Takei, Teng, Wan, Wan, Wang, Warring, Yang, Yi, Yi, Yu, Zhang, Zhang, Zhang, Zhao, Zhu   +49 more
core   +1 more source

Synthesis and Functional Evaluation of DNA-Assembled Polyamidoamine Dendrimer Clusters for Cancer Cell-Specific Targeting [PDF]

, 1954
SummaryWe sought to produce dendrimers conjugated to different biofunctional moieties (fluorescein [FITC] and folic acid [FA]), and then link them together using complementary DNA oligonucleotides to produce clustered molecules that target cancer cells ...
Choi, Youngseon, Thomas, Thommey, Kotlyar, Alina, Islam, Mohammad T., Baker, James R.   +4 more
core   +1 more source

Dendrimer-fullerenol soft-condensed nanoassembly [PDF]

, 2012
Nanoscale assembly is an area of research that has vast implications for molecular design, sensing, nanofabrication, supramolecular chemistry, catalysis, and environmental remediation.
Bhattacharya, Priyanka, Brown, Jared, Chen, Pengyu, Chen, Ran, Ke, Pu Chun, Kim, Seung Ha, Lamm, Monica, Lamm, Monica, Spuches, Anne   +8 more
core   +3 more sources

Molecular interactions between dimethoxycurcumin and Pamam dendrimer carriers

International Journal of Pharmaceutics, 2007
Dimethoxycurcumin, a lipophilic analog of curcumin found as a major pigment in the Indian species turmeric (Curcuma longa Linn.), is known to possess significant activity against various cancer cell lines, but its use as an anticancer drug is hindered by its poor water solubility.
Markatou, E., Gionis, V., Chryssikos, G.D., Hatziantoniou, S., Georgopoulos, A., Demetzos, C.   +5 more
openaire   +4 more sources

Lipodendriplexes: A promising nanocarrier for enhanced nucleic acid delivery [PDF]

, 2019
The main objective of the current study was to developed an optimized system for enhanced nucleic acid delivery with minimum cytotoxicity. For efficient therapeutic gene delivery, PAMAM dendrimer, with ethylenediamine core was chosen due to its ...
Tariq, Imran
core   +1 more source

PAMAM-calix-dendrimers as carriers for 5-fluorouracil: complexation, aggregation, andin vitroantitumor activity

Chimica Techno Acta
Despite a number of serious challenges and limitations in clinical use, drug therapy is considered one of the most common approaches to treating cancer. However, many types of cancer become resistant to antitumor drugs.
Pavel Padnya, Ilona Svintsova, Igor Shiabiev, Dmitry Pysin, Olga Mostovaya, Bahdan Ranishenka, Alesia Stanavaya, Viktar Abashkin, Dzmitry Shcharbin, Anastasia Nazarova, Ivan Stoikov   +10 more
doaj   +1 more source