Results 21 to 30 of about 13,061 (210)

Polyethylene glycolated PAMAM dendrimers-Efavirenz conjugates

International Journal of Pharmaceutical Investigation, 2014
The preparation of novel PEGylated PAMAM (poly-amidoamine) dendrimers for delivery of anti-HIV drug Efavirenz is reported.About 5.0 G PAMAM dendrimers are prepared by ethylene diamine core via Michael addition by divergent method. PEGylation is done by polyethylene glycol 600 using epichlorhydrin as linker.
Pyreddy, Suneela, Kumar, Pandurangan Dinesh, Kumar, Palanirajan Vijayaraj   +2 more
openaire   +3 more sources

Analysis of Biotinylated Generation 4 Poly(amidoamine) (PAMAM) Dendrimer Distribution in the Rat Brain and Toxicity in a Cellular Model of the Blood-Brain Barrier

Molecules, 2013
Dendrimers are highly customizable nanopolymers with qualities that make them ideal for drug delivery. The high binding affinity of biotin/avidin provides a useful approach to fluorescently label synthesized dendrimer-conjugates in cells and tissues.
Heather A. Bullen, Kristi L. Haik, Celeste Morris, Steven Wall, Anthony Haskamp, Megan Caroway, Michael Hester, Robert Spaulding, Brett Rossow, Ruth Hemmer, Andrew Hall   +10 more
doaj   +1 more source

Use of poly (amidoamine) dendrimer for dentinal tubule occlusion: a preliminary study. [PDF]

PLoS ONE, 2015
The occlusion of dentinal tubules is an effective method to alleviate the symptoms caused by dentin hypersensitivity, a significant health problem in dentistry and daily life.
Tianda Wang, Sheng Yang, Lei Wang, Hailan Feng   +3 more
doaj   +1 more source

Dataset of 1H-nuclear magnetic resonance and mass spectra of surface modified Poly(amidoamine) dendrimers with LFC131 peptide

Data in Brief, 2021
In the present article, we describe the spectroscopic data of poly(amido)amine dendrimers generation 5.0 (G5 PAMAM) conjugated with LFC131 peptide at different specified reaction points.
Chuda Chittasupho, Chaiyawat Aonsri, Witcha Imaram   +2 more
doaj   +1 more source

Practical computational toolkits for dendrimers and dendrons structure design [PDF]

, 2017
Dendrimers and dendrons offer an excellent platform for developing novel drug delivery systems and medicines. The rational design and further development of these repetitively branched systems are restricted by difficulties in scalable synthesis and ...
A Kwok, A Quintana, AM Naylor, BP Roberts, C Yu, CD Schwieters, CW Brown, D Astruc, D Jishkariani, D Luong, DA Case, E Vacas-Córdoba, F Razmimanesh, G Kleywegt, G Kleywegt, H Arima, H-J Hsu, Helena F. Florindo, HJC Berendsen, HM Berman, I Jatczak-Pawlik, I Tanis, JC Phillips, K Öztürk, KT Al-Jamal, LF Pinto, LF Pinto, Liana C. Silva, M Bello, M Kalomiraki, M Zloh, Mire Zloh, MK Mishra, N Li, N Martinho, Nuno Martinho, R Alberto, S Ahmed, S Dong, S Ghosh, S Javor, S Raut, S Svenson, SH Kim, Steve Brocchini, Teresa Barata, TS Barata, TS Barata, TS Barata, TTC Nguyen, V Maingi, X Cai, Y Liu   +52 more
core   +3 more sources

Amine functionalization of cholecyst-derived extracellular matrix with generation 1 PAMAM dendrimer [PDF]

, 2008
This document is the unedited author's version of a Submitted Work that was subsequently accepted for publication in Biomacromolecules, copyright © American Chemical Society after peer review.
Angele P., Babensee J. E., Badylak S., Badylak S. F., Badylak S. F., Badylak S. F., Billiar K., Brody S., Burugapalli K., Buttafoco L., Chandrasekar D., Charulatha V., Chen R. R., Coburn J. C., Curotto E., Domanski D. M., Duan X., Duan X., Duan X., DuBay D. A., Dumas P., Ferrando J. M., Garcia Y., Grinnell F., Henry J. A., Hodde J., Hodde J. P., Ko R., Kochupura P. V., Koizumi N. J., Lee J. M., Lee S. H., Liang H. C., Ma L., Ma Z., Malafaya P. B., McDevitt C. A., McKegney M., Meinert M., Najlah M., Nourse A., Olde Damink L. H., Olde Damink L. H., Osborne C. S., Papagiannaros A., Pek Y. S., Pieper J. S., Saito H., Sokolsky-Papkov M., Tabata Y., Tessmar J. K., Unsworth J. M., van Wachem P. B., van Wachem P. B., van Wachem P. B., Voytik-Harbin S. L., Wissink M. J., Wissink M. J., Wolkers W. F., Yee N., Zhong S., Zilla P.   +61 more
core   +1 more source

Biogenic and synthetic polyamines bind cationic dendrimers.

PLoS ONE, 2012
Biogenic polyamines are essential for cell growth and differentiation, while polyamine analogues exert antitumor activity in multiple experimental model systems, including breast and lung cancer.
Jean-Sebastian Mandeville, Phillipe Bourassa, Thekkumkattil John Thomas, Heidar-Ali Tajmir-Riahi   +3 more
doaj   +1 more source

Dendritic glycopolymers based on dendritic polyamine scaffolds: view on their synthetic approaches, characteristics and potential for biomedical applications [PDF]

, 2014
In this review we highlight the potential for biomedical applications of dendritic glycopolymers based on polyamine scaffolds. The complex interplay of the molecular characteristics of the dendritic architectures and their specific interactions with ...
Abbott, Agarwal, Agashe, Agashe, Agrawal, Agrawal, Albersheim, Albertazzi, Amir, Anajwala, Andre, Andre, Andre, Anna Janaszewska, Antoni, Antoni, Aoi, Appelhans, Appelhans, Arima, Arima, Arima, Arima, Arima, Baek, Baigude, Baigude, Baker, Bandaru, Barbara Klajnert-Maculewicz, Barner-Kowollik, Bettinger, Bhadra, Bhadra, Boas, Bogdan, Bogdan, Bojarova, Borges, Boye, Branco de Barros, Branderhorst, Branson, Brigitte Voit, Calderon, Carlmark, Carlmark, Chabre, Chabre, Chabre, Chen, Chen, Cheng, Cheng, Choudhury, Ciepluch, Ciolkowski, Ciolkowski, Cloninger, Conte, Cook, Cummins, Danishefsky, de Paz, Diebold, Dietmar Appelhans, Dolenc, Dominguez, Dondoni, Drzewinska, Duncan, Duncan, Dutta, Dutta, Dutta, Dutta, Ennen, Erbacher, Fajac, Filimon, Fischer, Franiak-Pietryga, Gabius, Gajbhiye, Gajbhiye, Gajbhiye, Gajbhiye, Gajbhiye, Garcia-Vallejo, Garg, Ghirardello, Gorelik, Gorityala, Gringas, Grobarova, Grosse, Grosse, Grosse, Gupta, Gupta, Gutsch, Hatano, Hauptmann, Hauptmann, He, Hu, Höbel, Iha, Ikeda, Imberty, Ina, Jain, Jain, Jain, Jain, Jain, Jain, Janaszewska, Janaszewska, Jararaman, Jararaman, Jayaraman, Jia, Joanna Lazniewska, Kade, Kaminskas, Kantchev, Kempe, Kensinger, Kensinger, Kesharwani, Kiessling, Kihara, Kihara, Kim, Klajnert, Klajnert, Klajnert, Klajnert, Klajnert, Klementieva, Klementieva, Kottari, Krist, Ku, Kuhlbeil, Kumar, Kunath, Kuo, Kuo, Kurmi, Köth, Laurino, Leclercq, Lee, Li, Lindhorst, Liu, Liu, Llinares, Lopez-Marin, Ma, Majoinen, Malik, Maly, Mangold, Marradi, Martos, Martínez, Matsushita, Matsushita, McCarthy, McCarthy, McCarthy, McCarthy, McNermy, Medina, Medina, Medina, Mignani, Mignani, Mignani, Mignani, Milowska, Misra, Mkandawire, Monsigny, Motoyama, Nahar, Narayan, Needham, Nepogodiev, Nicolas, Niederhafener, Niederhafener, Niederhafener, Ogiso, Oka, Oka, Ottaviani, Palcic, Paolino, Paolino, Papadopoulos, Park, Park, Park, Park, Patel, Pedziwiatr-Werbicka, Percec, Polikarpov, Richter, Robb, Ross, Roy, Roy, Roy, Roy, Rudd, Röckendorf, Sakamoto, Santoyo-Gonzáles, Santoyo-Gonzáles, Sapsford, Sashiwa, Satoh, Schengrund, Seah, Sethi, Shah, Sharma, Sharon, Shaunak, Shcharbin, Shiao, Sinha, Solassol, Stefani, Sun, Supattapone, Svenson, Svenson, Szewczyk, Szulc, Szulc, Tekade, ten Brummelhuis, Thünemann, Ting, Touaibia, Tripp, Tsutsumiuchi, Turnbull, Vacas Córdoba, Vepŕek, Wada, Wada, Walter, Wang, Wang, Wang, Warenda, Wasiak, Wijagkanalan, Wolfenden, Woller, Wood, Wu, Wu, Zanini, Zanini, Zanta, Zhang, Ziemba, Ziemba, Ziemba, Ziemba, Zinselmeyer   +278 more
core   +2 more sources

Hydrogel of Ketoconazole and PAMAM Dendrimers: Formulation and Antifungal Activity

Molecules, 2012
Ketoconazole (KET), an imidazole derivative with well-known antifungal properties, is lipophilic and practically insoluble in water, therefore its clinical use has some practical disadvantages.
Elzbieta Tryniszewska, Pawel Tomasz Sacha, Piotr Wieczorek, Magdalena Wroblewska, Katarzyna Winnicka   +4 more
doaj   +1 more source

G4.5 Pamam Dendrimer-Risperidone: Biodistribution and Behavioral Changes in In Vivo Model [PDF]

, 2013
Dendritic polymers are considered as emerging and outstanding carriers as modern medicinal systems due to their derivatisable branched architecture and possibility to modify them in numerous ways.
Alonso, Silvia del Valle, Bichara, Darío Román, Chiaramoni, Nadia Silvia, del Rio Zabala, Nahuel Eduardo, Marotta, Cristian Hernán, Prieto, Maria Jimena, Simonetta, Sergio Hernan   +6 more
core   +2 more sources