Results 151 to 160 of about 5,491 (175)
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Pannexin-1 channels in epilepsy
Neuroscience Letters, 2019Pannexin-1 (Panx1) expression is raised in several animal seizure models and in resected human epileptic brain tissue, suggesting relevance to epilepsy. Multiple factors that are characteristic of seizures are thought to regulate Panx1 channel opening, including elevated levels of extracellular K+.
Mark S, Aquilino +3 more
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Pannexin: To gap or not to gap, is that a question?
IUBMB Life (International Union of Biochemistry and Molecular Biology: Life), 2006Vertebrates express two families of gap junction proteins: the well characterized connexins and the recently discovered pannexins. The latter are related to invertebrate innexins. Here we present the hypothesis that pannexins, rather than providing a redundant system to gap junctions formed by connexins, exert a physiological role as nonjunctional ...
Gerhard, Dahl, Silviu, Locovei
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Connexin-Pannexin duality in glioblastoma
Cell and Tissue ResearchGlioblastoma (GBM) is the most aggressive primary brain tumour in adults, characterized by extensive heterogeneity and diffuse invasion. Increasing evidence highlights the role of channel-forming proteins in glioma biology. Connexins (Cxs) and Pannexins (Panxs) are two structurally related yet functionally distinct protein families that mediate ...
Rehanna, Kanji +2 more
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2022
Die hypoxische pulmonale Vasokonstriktion ist ein durch alveoläre Hypoxie ausgelöster aktiver physiologischer Mechanismus, der den pulmonalen Blutfluss aus sauerstoffärmeren Bereichen der Lunge in besser ventilierte Regionen umleitet, um die Sauerstoffversorgung zu optimieren. Die molekularen Signalwege, welche die hypoxische pulmonale Vasokonstriktion
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Die hypoxische pulmonale Vasokonstriktion ist ein durch alveoläre Hypoxie ausgelöster aktiver physiologischer Mechanismus, der den pulmonalen Blutfluss aus sauerstoffärmeren Bereichen der Lunge in besser ventilierte Regionen umleitet, um die Sauerstoffversorgung zu optimieren. Die molekularen Signalwege, welche die hypoxische pulmonale Vasokonstriktion
openaire +1 more source
Mechanisms of Pannexin 1 (PANX1) Channel Mechanosensitivity and Its Pathological Roles
International Journal of Molecular Sciences, 2022Taolei Sun, Zhao Xinyue, Sun Taolei
exaly
American Journal of Physiology - Heart and Circulatory Physiology, 2021
Timothy Mcmahon +2 more
exaly
Timothy Mcmahon +2 more
exaly
Extrinsic and intrinsic apoptosis activate pannexin‐1 to drive NLRP 3 inflammasome assembly
EMBO Journal, 2019Kaiwen W Chen +2 more
exaly
Pannexin-1 Channels as Mediators of Neuroinflammation
International Journal of Molecular Sciences, 2021exaly