Results 171 to 180 of about 7,051 (198)
Rho Signaling Regulates Pannexin 1-mediated ATP Release from Airway Epithelia [PDF]
Journal of Biological Chemistry, 2011 ATP released from airway epithelial cells promotes purinergic receptor-regulated mucociliary clearance activities necessary for innate lung defense. Cell swelling-induced membrane stretch/strain is a common stimulus that promotes airway epithelial ATP ...
Dale W Laird +2 more
exaly +2 more sources
Some of the next articles are maybe not open access.
Related searches:
Related searches:
2009
Pannexins are a family of three vertebrate proteins that have moderate sequence homology with the innexin proteins, which compose gap junction channels in protostomes, including most invertebrates. However, it appears that in contrast to innexins, pannexins do not have the ability to form gap junction channels.
Gerhard Dahl, Andrew L. Harris
openaire +1 more source
Pannexins are a family of three vertebrate proteins that have moderate sequence homology with the innexin proteins, which compose gap junction channels in protostomes, including most invertebrates. However, it appears that in contrast to innexins, pannexins do not have the ability to form gap junction channels.
Gerhard Dahl, Andrew L. Harris
openaire +1 more source
Role of Connexins and Pannexins in the Pancreas
Pancreas, 2015The pancreas produces enzymes with a digestive function and hormones with a metabolic function, which are produced by distinct cell types of acini and islets, respectively. Within these units, secretory cells coordinate their functioning by exchanging information via signals that flow in the intercellular spaces and are generated either at distance ...
Cigliola Valentina +5 more
openaire +3 more sources
Connexins and pannexins in Alzheimer’s disease
Neuroscience Letters, 2019By 2040 neurodegenerative diseases will become the world's second leading cause of death after cardiovascular disease (WHO). Major efforts are required to elucidate the underlying molecular and cellular mechanisms of neurodegenerative diseases. Connexin and pannexin membrane channel proteins are conduits through which neuronal, glial, and vascular ...
Christian, Giaume +4 more
openaire +3 more sources
Pannexin-1 channels in epilepsy
Neuroscience Letters, 2019Pannexin-1 (Panx1) expression is raised in several animal seizure models and in resected human epileptic brain tissue, suggesting relevance to epilepsy. Multiple factors that are characteristic of seizures are thought to regulate Panx1 channel opening, including elevated levels of extracellular K+.
Mark S, Aquilino +3 more
openaire +2 more sources
Pannexin: To gap or not to gap, is that a question?
IUBMB Life (International Union of Biochemistry and Molecular Biology: Life), 2006Vertebrates express two families of gap junction proteins: the well characterized connexins and the recently discovered pannexins. The latter are related to invertebrate innexins. Here we present the hypothesis that pannexins, rather than providing a redundant system to gap junctions formed by connexins, exert a physiological role as nonjunctional ...
Gerhard, Dahl, Silviu, Locovei
openaire +2 more sources
Connexin-Pannexin duality in glioblastoma
Cell and Tissue ResearchGlioblastoma (GBM) is the most aggressive primary brain tumour in adults, characterized by extensive heterogeneity and diffuse invasion. Increasing evidence highlights the role of channel-forming proteins in glioma biology. Connexins (Cxs) and Pannexins (Panxs) are two structurally related yet functionally distinct protein families that mediate ...
Rehanna, Kanji +2 more
openaire +2 more sources
2022
Die hypoxische pulmonale Vasokonstriktion ist ein durch alveoläre Hypoxie ausgelöster aktiver physiologischer Mechanismus, der den pulmonalen Blutfluss aus sauerstoffärmeren Bereichen der Lunge in besser ventilierte Regionen umleitet, um die Sauerstoffversorgung zu optimieren. Die molekularen Signalwege, welche die hypoxische pulmonale Vasokonstriktion
openaire +1 more source
Die hypoxische pulmonale Vasokonstriktion ist ein durch alveoläre Hypoxie ausgelöster aktiver physiologischer Mechanismus, der den pulmonalen Blutfluss aus sauerstoffärmeren Bereichen der Lunge in besser ventilierte Regionen umleitet, um die Sauerstoffversorgung zu optimieren. Die molekularen Signalwege, welche die hypoxische pulmonale Vasokonstriktion
openaire +1 more source
Pannexin Channels: The Emerging Therapeutic Targets
Current Drug Targets, 2014Intercellular communication plays a pivotal role in various physiological functions. This is mainly done through gap junctions and trans-membrane channels. The structural proteins forming these channels are different in vertebrates and invertebrates namely connexins and innexins respectively.
Misbahuddin, Mohammad, Hamed Said, Habib
openaire +2 more sources