Results 161 to 170 of about 1,892 (187)
Spermatogenesis, 2011 Gap junctions and connexins are critical for coordinating cellular functions in complex epithelia. In recent years there has been increased interest in understanding the regulation and function of gap junctions in both the testis and epididymis. Studies in transgenic mice in which connexin 43 (Cx43) is mutated or is knocked down only in Sertoli cells ...
Daniel G Cyr
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Role of connexins and pannexins in cardiovascular physiology
Cellular and Molecular Life Sciences, 2015 Connexins and pannexins form connexons, pannexons and membrane channels, which are critically involved in many aspects of cardiovascular physiology.
Merlijn J Meens +2 more
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Expression and Roles of Pannexins in ATP Release in the Pituitary Gland
Endocrinology, 2011 Pannexins are a newly discovered three-member family of proteins expressed in the brain and peripheral tissues that belong to the superfamily of gap junction proteins.
Shuo Li, Ivana Bjelobaba, Zonghe Yan
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Connexins and Pannexins in Bone and Skeletal Muscle
Current Osteoporosis Reports, 2017 PURPOSE OF REVIEW: To discuss current knowledge on the role of connexins and pannexins in the musculoskeletal system. RECENT FINDINGS: Connexins and pannexins are crucial for the development and maintenance of both bone and skeletal muscle.
Lilian I Plotkin +2 more
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Pannexins, a family of gap junction proteins expressed in brain
Proceedings of the National Academy of Sciences of the United States of America, 2003 Database search has led to the identification of a family of proteins, the pannexins, which share some structural features with the gap junction forming proteins of invertebrates and vertebrates. The function of these proteins has remained unclear so far.
Roberto Bruzzone +2 more
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Pannexin expression in the cerebellum
The Cerebellum, 2006Pannexin1 and pannexin2 are members of the pannexin gene family which are widely expressed in the central nervous system. Here we present an overview of pannexin expression and distribution in the mouse cerebellum. Pannexin1 and pannexin2 are expressed in the Purkinje cells and in some cells of the granule cell layer. Pannexin2 is also expressed in the
Arundhati, Ray +3 more
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Role of Connexins and Pannexins in the Pancreas
Pancreas, 2015The pancreas produces enzymes with a digestive function and hormones with a metabolic function, which are produced by distinct cell types of acini and islets, respectively. Within these units, secretory cells coordinate their functioning by exchanging information via signals that flow in the intercellular spaces and are generated either at distance ...
Cigliola Valentina +5 more
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Purinergic Signaling in Gut Inflammation: The Role of Connexins and Pannexins
Frontiers in Neuroscience, 2016 Purinergic receptors play an important role in inflammation, and can be activated by ATP released via pannexin channels and/or connexin hemichannels. The purinergic P2X7 receptor (P2X7R) is of interest since it is involved in apoptosis when activated ...
Paul P Bertrand, Lu Liu
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