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Keracunan Parasetamol Pada Kucing Dan Anjing: Gejala Klinis dan Terapi

Jurnal Ilmu Peternakan dan Veteriner Tropis, 2020
Acetaminophen, commonly known as paracetamol, is a non-steroidal anti-inflammatory drug commonly used in human medicine for its antipyretic and analgesic action.
Yanuartono Yanuartono, Alfarisa Nururrozi, Soedarmanto Indarjulianto, Slamet Raharjo, Hary Purnamaningsih, Nurman Haribowo   +5 more
doaj   +3 more sources

Prunus laurocerasus L. Extracts Prevent Paracetamolinduced Nephrotoxicity by Regulating Antioxidant Status: An Experimental Animal Model

Hittite Journal of Science and Engineering, 2022
Paracetamol is a popular analgesic drug and its overdose may cause toxicity in the kidney. Prunus laurocerasus L. (PL) is an important folklore medicinal plant that has antioxidant properties.
Kaan Kaltalıoğlu
doaj   +1 more source

Chlorzoxazone reduced the paracetamol-induced toxicity via competitive inhibition of CYP2E1-mediated metabolism

Future Journal of Pharmaceutical Sciences, 2023
Background Drug metabolism is crucial to attaining the therapeutic index of any drug. The metabolism and elimination of the drugs are governed mainly by P-glycoprotein (P-gp) and Cytochrome P450 (CYP).
Ravindra Babu Pingili, Sridhar Vemulapalli, Manideep V. V. N. Gadamsetty, Divya Presingu, Ruthvik Katuri, Vijayalakshmi Rachamsetty, Naveen Babu Kilaru   +6 more
doaj   +1 more source

Paracetamol as a Post Prandial Marker for Gastric Emptying, A Food-Drug Interaction on Absorption. [PDF]

PLoS ONE, 2015
The use of paracetamol as tool to determine gastric emptying was evaluated in a cross over study. Twelve healthy volunteers were included and each of them consumed two low and two high caloric meals.
R Bartholomé, B Salden, M F Vrolijk, F J Troost, A Masclee, A Bast, G R Haenen   +6 more
doaj   +1 more source

Crystallization of Form II Paracetamol with the Assistance of Carboxylic Acids toward Batch and Continuous Processes

Pharmaceutics, 2022
Form II paracetamol has captured the interest of researchers due to its improved compressibility. However, its low stability has made it difficult to be produced on a large scale with good reproducibility.
Kuan-Lin Yeh, Hung-Lin Lee, Tu Lee
doaj   +1 more source

Paracetamol-induced changes of haematobiochemical and oxidative stress parameters in rat blood: Protective role of vitamin C and β-glucan [PDF]

Kragujevac Journal of Science, 2016
Paracetamol (acetaminophen) is widely used as an over-the-counter analgesic and antipyretic drug. The aim of this study was to investigate the possible protective effects of vitamin C (100mg/kg/day i.p.) and β-glucan (40 mg/kg/day i.p.) on altered ...
Matić Miloš M., Milošević Marija D., Paunović Milica G., Ognjanović Branka I., Štajn Andraš Š., Saičić Zorica S.   +5 more
doaj   +1 more source

Ameliorative effects of frankincense oil on rats treated with a minimum toxic dose of paracetamol [PDF]

Journal of Medical and Life Science, 2023
Paracetamol is a widely used analgesic and antipyretic drug, but its long-term usage has been associated with potential toxicity. The goal of this study was to investigate how frankincense oil prevents paracetamol toxicity. The study included twenty male
Aml Talaat, Yomna Elgendy, Heba Mohamed, Nouran Saed, Noran Abd Elrouf, Hend Elgendy, Hagar Elbalakousy, Nourhan El hantoshy, Mohammed Elmezaien, Youssef Sayed, Yosry El . Hekal, Mohamed Gabr, 1. Nada Badr   +12 more
doaj   +1 more source

Is paracetamol prescribed appropriately in elderly patients admitted for a fall? – A Geriatrician’s perspective

Proceedings of Singapore Healthcare, 2023
Background Paracetamol is a commonly used analgesic among older adults. There have been reports of adverse events with chronic paracetamol use even at therapeutic doses. The objective of this clinical audit is twofold – 1.
Angela Frances Hui Wen Yap, Trishpal Kaur Dhaliwal, Surendra Doraiswamy Varman   +2 more
doaj   +1 more source

In vitro demonstration of herbal exacerbation of paracetamol-induced hepatotoxicity

Phytomedicine Plus, 2022
Background: Paracetamol (acetaminophen) is one of the most accessible pharmaceutical analgesic and antipyretic agents. Similarly, traditional herbal medicines including Psoralea corylifolia, Astragalus propinquus and Atractylodes macrocephala have been ...
Susan M. Britza, Rachael Farrington, Roger W. Byard, Ian F. Musgrave   +3 more
doaj   +1 more source

Egyptian perspectives on potential risk of paracetamol/acetaminophen-induced toxicities: Lessons learnt during COVID-19 pandemic

Toxicology Reports, 2022
Paracetamol/Acetaminophen was widely used as a first-line antipyretic and analgesic for COVID-19 patients without giving any attention to the potential risk of related toxicities.
Enas M.A. Mostafa, Ayat M. Tawfik, Khadiga M. Abd-Elrahman   +2 more
doaj   +1 more source