Results 21 to 30 of about 206,427 (382)
Interrupted time-series analysis of regulations to reduce paracetamol (acetaminophen) poisoning. [PDF]
PLoS Medicine, 2007 Paracetamol (acetaminophen) poisoning is the leading cause of acute liver failure in Great Britain and the United States. Successful interventions to reduced harm from paracetamol poisoning are needed.
Oliver W Morgan +2 more
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In vitro demonstration of herbal exacerbation of paracetamol-induced hepatotoxicity
Phytomedicine Plus, 2022 Background: Paracetamol (acetaminophen) is one of the most accessible pharmaceutical analgesic and antipyretic agents. Similarly, traditional herbal medicines including Psoralea corylifolia, Astragalus propinquus and Atractylodes macrocephala have been ...
Susan M. Britza +3 more
doaj +1 more source
Paracetamol cardiotoxicity [PDF]
Postgraduate Medical Journal, 1993 Summary A 29 year old man with a significant paracetamol overdose was found to have an abnormal electrocardiograph which, in the absence of hepatic encephalopathy, was considered due to a direct cardiotoxic effect of the drug. A functional coronary insufficiency resulting from inhibition of endothelium-derived relaxing factor secondary ...
A, Armour, S D, Slater
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Antioxidants, 2021 Liver damage induced by paracetamol overdose is the main cause of acute liver failure worldwide. In order to study the hepatoprotective effect of Sanghuangporus sanghuang mycelium (SS) on paracetamol-induced liver injury, SS was administered orally every
Wen-Ping Jiang +8 more
semanticscholar +1 more source
Toxicology Reports, 2022 Paracetamol/Acetaminophen was widely used as a first-line antipyretic and analgesic for COVID-19 patients without giving any attention to the potential risk of related toxicities.
Enas M.A. Mostafa +2 more
doaj +1 more source
iScience, 2023 Summary: Prenatal paracetamol exposure has been associated with neurodevelopmental outcomes in childhood. Pharmacoepigenetic studies show differences in cord blood DNA methylation between unexposed and paracetamol-exposed neonates, however, causality and
Mari Spildrejorde +11 more
doaj +1 more source
Acetaminophen (Paracetamol) [PDF]
Journal of Pain and Symptom Management, 2013 Therapeutic Reviews aim to provide essential independent information for health professionals about drugs used in palliative and hospice care. Additional content is available on www.palliativedrugs.com. Country-specific books (Hospice and Palliative Care Formulary USA, and Palliative Care Formulary, British and Canadian editions) are also available and
Robert, Twycross +3 more
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Paracetamol – An old drug with new mechanisms of action
Clinical and Experimental Pharmacology and Physiology, 2020 Paracetamol (acetaminophen) is the most commonly used over‐the‐counter (OTC) drug in the world. Despite its popularity and use for many years, the safety of its application and its mechanism of action are still unclear.
G. Przybyła +2 more
semanticscholar +1 more source
Liver injury induced by paracetamol and challenges associated with intentional and unintentional use
World Journal of Hepatology, 2020 Drug induced liver injury (DILI) is a common cause of acute liver injury. Paracetamol, also known as acetaminophen, is a widely used anti-pyretic that has long been established to cause liver toxicity once above therapeutic levels.
L. Rotundo, N. Pyrsopoulos
semanticscholar +1 more source
A New Sensor Based on Graphite Screen Printed Electrode Modified With Cu-Nanocomplex for Determination of Paracetamol [PDF]
Nanochemistry Research, 2017 Paracetamol is a non-steroidal anti-inflammatory drug used as an antipyretic agent for the alternative to aspirin. Conversely, the overdoses of paracetamol can cause hepatic toxicity and kidney damage.
Hadi Beitollai, Reza Zaimbashi
doaj +1 more source