Results 51 to 60 of about 8,981 (169)

The paraoxonase 1, paraoxonase 2 and paraoxonase 3 in humans

Biochemia medica, 2011
The paraoxonase gene family in humans includes three members: pon1, pon2 and pon3. The products of those three genes are the following enzymes: paraoxonase 1 (PON1), paraoxonase 2 (PON2) and paraoxonase 3 (PON3). PON1 is mainly associated with a high density lipoprotein (HDL). A small amount of this enzyme is also bound to very low-density lipoprotein (
Rumora, Lada, Barišić, Karmela, Grdić Rajković, Marija   +2 more
openaire   +1 more source

Effect of four weeks of endurance training on serum level of paraoxonase-1 and lipid profile in non-athlete obese men

مجله دانشگاه علوم پزشکی گرگان, 2014
Background and Objective: Paraoxonase-1 is an important factor in preventing lipid oxidation and formation of oxidized low-density lipoprotein. There are conflicting reports on the impact of physical activity on serum level of Paraoxonase-1.
Amouzad Mahdirejei T, Berarei AR, Farzanegei P, Ahmadi M   +3 more
doaj  

The Effect of Atherogenic Diet with or without Enzyme Inhibitors on the Incidence and Progress of Atherosclerosis in Rabbits [PDF]

Journal of Cardiovascular and Thoracic Research, 2011
PON1 (Paraoxonase – 1) is an esterase enzyme which is associated with high density lipoprotein (HDL). The enzyme prevents the peroxidation of low density lipoprotein (LDL).
Masouad Pezeshkian, Akbar Darbin, Mohammad Reza Rashidi, Amir Mansor Vatankhah, Zahra Golmohammadi, Abbas Afrasiabi, Mohammad Nouri   +6 more
doaj  

Multiomics Research Strategies in Cancer: A Growing and Innovative Field

MedComm, Volume 7, Issue 4, April 2026.
This review highlights multiomics strategies in cancer research, focusing on integration methods from genomics to microbiomics. Using colorectal cancer as a key example, it discusses biomarker discovery, data integration via deep learning, and the roles of single‐cell and spatial omics.
Zhenhua Du, Xiaomei Liu, Zhi Lv, Bengang Wang, Yu Xia, Wala Abduljabbar Mohammed Al‐Duais, Lirong Yan, Fuqiang Zhang, Yanke Li   +8 more
wiley   +1 more source

Potential neuroprotective and therapeutic agents and their mechanisms for irradiation‐induced brain injury

Ibrain, Volume 12, Issue 1, Page 96-122, Spring 2026.
In this review, agents such baicalein, troxerutin, epigallocatechin gallate, quercetin, melatonin, valproic acid, lithium, neurosteroid progesterone, as well as minocycline have been implicated as neuroprotective agents for irradiation‐induced neurological deficits. Also, agents such as glucocorticoids, methylphenidate, vitamin E, bisdemethoxycurcumin,
Seidu A. Richard, Vivian Kapio Abem, Sagor Kumar Roy   +2 more
wiley   +1 more source

Evaluation of paraoxonase, malondialdehyde, and lipoprotein levels in patients with asymptomatic cholelithiasis

The Saudi Journal of Gastroenterology, 2014
Background/Aim: To compare lipoprotein and malondialdehyde levels and paraoxonase-1 activity between subjects with asymptomatic cholelithiasis and controls.
Aytac Atamer, Ayse O Kurdas-Ovunc, Atakan Yesil, Yildiz Atamer   +3 more
doaj   +1 more source

Defective high‐density lipoprotein lipoprotection in type 2 diabetes during acute myocardial infarction is rescued by apolipoprotein M/sphingosine‐1‐phosphate loading

Diabetes, Obesity and Metabolism, Volume 28, Issue 3, Page 2175-2182, March 2026.
Abstract Aims Mortality of patients with type 2 diabetes (T2D) after acute myocardial infarction (AMI) is tremendous and massively increased compared to non‐T2D individuals. The reasons are unclear. High‐density lipoprotein (HDL) conducts lipoprotection during AMI, leading to improved outcomes.
Jens Vogt, Marcel Benkhoff, Nathalie H. Schröder, Hao Hu, Lisa Dannenberg, Petra Keul, Theresia Sarabhai, Kálmán Benedikt Bódis, Tobias Zeus, Philipp Wollnitzke, Malte Kelm, Amin Polzin, Bodo Levkau   +12 more
wiley   +1 more source

Climate Change, Local Harvests and Marine Contamination: A Perspective on Cetacean Populations and Coastal Whaling Communities

Aquatic Conservation: Marine and Freshwater Ecosystems, Volume 36, Issue 2, February 2026.
ABSTRACT Cetaceans are indicators of ocean health, influence marine ecosystem dynamics and hold socio‐economic importance for coastal whaling communities. Yet whale–whaler relationships remain poorly understood and are increasingly compromised under the triple planetary crisis of climate change, biodiversity loss and pollution. Here, we briefly outline
Melissa A. McKinney, Jeremy J. Kiszka
wiley   +1 more source

Paraoxonase-1 and Early-Life Environmental Exposures

Annals of Global Health, 2016
Acute and chronic exposures to widely used organophosphorus (OP) insecticides are common. Children's detoxification mechanisms are not well developed until several years after birth. The increased cases of neurodevelopmental disorders in children, together with their increased susceptibility to OP neurotoxicity cannot be explained by genetic factors ...
Marsillach, Judit, Furlong, Clement E., COSTA, Lucio Guido   +2 more
openaire   +5 more sources

Mutual Influences between Nitric Oxide and Paraoxonase 1 [PDF]

Antioxidants, 2019
One of the best consolidated paradigms in vascular pharmacology is that an uncontrolled excess of oxidizing chemical species causes tissue damage and loss of function in the endothelial and subendothelial layers. The fact that high-density lipoproteins play an important role in preventing such an imbalance is integrated into that concept, for which the
Moya, Carlos, Máñez Aliño, Salvador, Marín Vázquez, Marta   +2 more
openaire   +3 more sources