Results 51 to 60 of about 29,702,919 (203)

Oral squamous cell carcinoma and serum paraoxonase 1

, 2013
Background: Serum paraoxonase 1 is involved in mechanisms that protect cells from oxidative stress damage. This study aimed to investigate the correlation between serum paraoxonase 1 activity and polymorphisms in patients with oral squamous cell ...
AYDIN, S., Isbir, T., Toptas, B., Metin, Z. Boy, Hafiz, G., Cakmakoglu, B., Unur, Meral   +6 more
core   +1 more source

Environmental Pesticide Exposure in the Etiology of Pediatric Brain Tumors and Leukemia: A Scoping Review of Epidemiological Studies

International Journal of Cancer, Volume 159, Issue 6, Page 1360-1384, 15 September 2026.
ABSTRACT Pediatric cancer is a significant cause of morbidity and mortality in children. The etiologies of pediatric cancer are largely unknown, but environmental pesticide exposures are likely to contribute. Chronic low‐dose exposure to pesticide mixtures through drinking water is a growing concern in agricultural communities.
Grace N. VanDeSteeg, Alyssa R. Russum, Matthew R. Sandbulte, Eleanor G. Rogan, Martha G. Rhoades   +4 more
wiley   +1 more source

The altered expression of Paraoxonase 1 in the gastric carcinoma.

, 2018
94 Background: High doses inadequate removal of reactive oxygen species result in oxidative stress, which may cause severe metabolic malfunctions and damage to biological molecules including DNA An elevated oxidative status has been found in many types
Jin Soo Kim, Sung Soo Kim
core   +1 more source

Marked Long‐Term Improvement in Lung Function in Melanoma Differentiation–Associated Protein 5 Antibody–Positive Dermatomyositis Patients: Experience of a Single‐Center Longitudinal Cohort in North America

Arthritis Care &Research, Volume 78, Issue 9, Page 1112-1122, September 2026.
Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation–associated protein 5 (MDA5) antibody–associated dermatomyositis (DM). Methods Thirty patients with MDA5 antibody–associated DM were identified in a single‐center longitudinal cohort of 352
Jenice X. Cheah, Sangmee S. Bae, Tiffany De Leon, Yuna Lee, Rong Guo, David Elashoff, Jennifer Wang, Ani Shahbazian, Christina Charles‐Schoeman   +8 more
wiley   +1 more source

The paraoxonase 1, paraoxonase 2 and paraoxonase 3 in humans

Biochemia medica, 2011
The paraoxonase gene family in humans includes three members: pon1, pon2 and pon3. The products of those three genes are the following enzymes: paraoxonase 1 (PON1), paraoxonase 2 (PON2) and paraoxonase 3 (PON3). PON1 is mainly associated with a high density lipoprotein (HDL). A small amount of this enzyme is also bound to very low-density lipoprotein (
Rumora, Lada, Barišić, Karmela, Grdić Rajković, Marija   +2 more
openaire   +1 more source

The human paraoxonase‐1 phenotype modifies the effect of statins on paraoxonase activity and lipid parameters [PDF]

British Journal of Clinical Pharmacology, 2008
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • It has been suggested that the human paraoxonase‐1 (PON1) genotype is an important determinant of the therapeutic response given to statin treatment.• It is also known that the PON1 activity status is a better predictor of coronary heart disease risk than any of the known PON1 genotypes.• Our goal was to ...
Hossein Z, Mirdamadi, Ferenc, Sztanek, Zoltan, Derdak, Ildiko, Seres, Mariann, Harangi, György, Paragh   +5 more
openaire   +2 more sources

Cardiovascular disease incidence and cancer risk in two large European prospective cohorts

International Journal of Cancer, Volume 159, Issue 5, Page 1139-1152, 1 September 2026.
What's new? Cardiovascular disease (CVD) and cancer share risk factors and biological mechanisms, raising questions about potential associations between the two, particularly regarding CVD duration and cancer onset. Whether CVD influences subsequent cancer risk, however, remains inconclusive.
Emma Fontvieille, Vivian Viallon, Laia Peruchet‐Noray, Quan Gan, N. Charlotte Onland‐Moret, Yvonne Koop, Anne Tjønneland, Nicola Patricia Bondonno, Verena Katzke, Rudolf Kaaks, Matthias B. Schulze, Catarina Schiborn, Calogero Saieva, Vittorio Simeon, Claudia Agnoli, Rosario Tumino, Fulvio Ricceri, Leila Luján‐Barroso, Maria‐José Sánchez, Conchi Moreno‐Iribas, Konstantinos K. Tsilidis, Marc J. Gunter, Adam Butterworth, Elio Riboli, Heinz Freisling, Pietro Ferrari   +25 more
wiley   +1 more source

Paraoxonase 1 in patients with diabetes mellitus [PDF]

, 2015
Humana serumska paraoksonaza 1 (PON1) je protein molekularne mase 43 kDa čija je katalitička aktivnost hidroliza organofosfatnih estera, aromatskih estera karboksilnih kiselina i karbamata.
Knežević, Josip
core   +1 more source

Quinoline and Phthalimide Substituted Silicon Phthalocyanines as Multi‐Target Inhibitors of Cholinesterases and Carbonic Anhydrases

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
Two novel axially substituted silicon phthalocyanines were synthesized and characterized. Compound 2a exhibited significantly enhanced inhibition of AChE, BChE, hCA I and hCA II, supported by molecular docking and SAR analysis, highlighting its potential as a multifunctional enzyme inhibitor with promising biological activity.
Seda Ünlü, Zeynep Köksal, Kevser Kübra Kırboğa, Fikriye Tuncel Elmalı   +3 more
wiley   +1 more source

Serum Paraoxonase-1 Activity in Prostate Cancer Patients Treated with Brachytherapy as a Measure of Irradiation Efficacy

Antioxidants, 2023
We investigated changes in the activity of antioxidant paraoxonase-1 (PON1) in patients with prostate cancer (PCa) undergoing radiotherapy (RT), as well as the relationship of the PON1 activity with the degree of PCa advancement.
Dorota Olszewska-Słonina, Miłosz Jasiński   +1 more
doaj   +1 more source