Results 161 to 170 of about 226,005 (247)

Ginsenoside Rg1 as a Multifunctional Therapeutic Agent: Pharmacological Properties, Molecular Mechanisms and Clinical Perspectives in Complementary Medicine

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Ginsenoside Rg1 (Rg1) from Panax ginseng shows multifunctional health effects. Although oral bioavailability is low and blood–brain barrier (BBB) penetration is limited, delivery systems such as liposomes and nanoparticles may improve exposure. Rg1 reduces inflammation/oxidative stress by inhibiting nuclear factor‐κB (NF‐κB) signaling and reactive ...
Hernán Cortés, Enrique Lima, Lorena Duarte‐Peña, Sheila I. Peña‐Corona, Zainab M. Almarhoon, Rajesh Kaverikana, Shivaprasad Shetty Mangalpady, Vinayaka Babu Shet, Nikshitha Manjeshwar, Javad Sharifi‐Rad, Jen‐Tsung Chen, Gerardo Leyva‐Gómez, William N. Setzer, Daniela Calina   +13 more
wiley   +1 more source

The role of mitophagy in female reproductive system diseases: from molecular mechanisms to therapeutic strategies. [PDF]

Front Endocrinol (Lausanne)
Zhao H, Wang Y, Han H, Jiang Y, Ji X, Zhang Y.   +5 more
europepmc   +1 more source

Pinellia pedatisecta Schott‐Derived Exosome‐Like Nanovesicles Promote Apoptosis in Colorectal Cancer by Regulating the Lysosome‐Mediated Mitophagy Pathway

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Pinellia pedatisecta Schott‐derived exosome‐like nanovesicles (PPS‐ELNs) are efficiently taken up by colorectal cancer (CRC) cells and exhibit tumor‐targeting properties. Mechanistically, PPS‐ELNs suppress tumor progression by inhibiting the proliferation of CRC cells and promoting apoptosis through regulation of the lysosome‐mediated mitophagy pathway.
Pingsheng Zhou, Qingling Zhang, Xiaotao Zhou, Ge Zhang, Shiping Cheng   +4 more
wiley   +1 more source

Superoxide signals for the mitophagy of dysfunctional mitochondria to maintain quality control. [PDF]

Redox Biol
Curtis WM, Bradshaw PC.
europepmc   +1 more source

A First Quantitative Assessment of Soil Health at European Scale Considering Soil Genesis

Journal of Plant Nutrition and Soil Science, Volume 189, Issue 1, Page 6-16, February 2026.
ABSTRACT Background Soil health degradation is a major threat to European food security, biodiversity, and climate stability. While scientists have debated how to define soil health during recent decades, a quantifiable framework for monitoring, management, and policy remains lacking.
Christine Alewell, Surya Gupta, Jerome Poulenard, Noémie Niquille, Antonia Kaiser, Nima Shokri, Simon Scheper, Miriam Gross‐Schmölders, David A. Robinson, Grant Campbell, Cezary Kabala, Friederike Lang, Nancy Dise, Panos Panagos, Pasquale Borrelli   +14 more
wiley   +1 more source

Galectin-3 directs mitophagy in response to Parkin-/proteasome-dependent rupture of mitochondrial outer membrane. [PDF]

Biol Direct
Liu PH, Lin YS, Chu WH, Sun WT, Huang PY, Huang JR, Chiang WC.   +6 more
europepmc   +1 more source

Description of veterinary events and risk factors for fatality in National Hunt flat racing Thoroughbreds in Great Britain (2000-2013) [PDF]

, 2017
Altman, Dohoo, Henley, Hosmer, Kawcak, Lyle, McKee, Mohammed, Parkin, Parkin, Parkin, Parkin, Reardon, Rosanowski, Smith, Whitton, Williams   +16 more
core   +2 more sources

Parkin Pigs

, 2020
openaire   +2 more sources

Effect of Denervation on Skeletal Muscle Mitochondria in Heterozygous mtDNA Mutator Mice

FASEB BioAdvances, Volume 8, Issue 2, February 2026.
Denervation induces mitochondrial dysfunction and oxidative stress in skeletal muscle. In PolG(+/mut) mice, denervation led to reduced mitochondrial DNA copy number and a pronounced upregulation of the antioxidant enzyme catalase, despite comparable levels of muscle atrophy, mitochondrial content, and mitochondrial dynamics‐related proteins compared to
Takanaga Shirai, Hideto Hanakita, Kohei Takeda, Yu Kitaoka, Kaori Ishikawa, Kazuto Nakada, Tohru Takemasa   +6 more
wiley   +1 more source

Lifespan‐Extending Endogenous Metabolites

Aging Cell, Volume 25, Issue 2, February 2026.
Endogenous metabolites act as mediators of longevity by modulating conserved cellular pathways. We summarize mechanistic evidence linking specific metabolites to lifespan and healthspan benefits across model systems, with discussion of clinical evidence, translational opportunities, and remaining knowledge gaps.
Yizhou Jiang, Jing‐Dong J. Han
wiley   +1 more source