Results 81 to 90 of about 226,005 (247)
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Osteoarthritis (OA) is a prevalent degenerative joint disease. This study combines bioinformatics analysis with in vivo and in vitro experiments to elucidate the molecular mechanisms through which melatonin (MT) regulates mitophagy to alleviate OA.
Chao Huang +4 more
wiley +1 more source
Working with graphic design students to promote `Land of Lost Content¿ at Leeds Met. [PDF]
, 2009 yesAs Leeds Metropolitan is a university of festivals and partnerships, the library was given the opportunity this year to host a festival to promote the library and all its services to the university.
Carver, Kirsty, Parkin, C.
core
ESC Heart Failure, Volume 12, Issue 2, Page 1490-1491, April 2025.
Özant Helvacı +4 more
wiley +1 more source
Limnology and Oceanography: Methods, EarlyView.Abstract The Groundwater Automated Chemical Examiner (GrACE) is an automated analytical system of integrated sensors for the field‐based measurement of chemical and physical properties of groundwater. The GrACE system was designed to explore parameters influencing the dissolved concentrations of carbon dioxide (pCO2) and methane (pCH4) in groundwater ...
Madeline McChesney Every +2 more
wiley +1 more source
Estudi de la regulació de la proteïna proapoptòtica RTP801 per l’E3 ubiquitina lligasa parkina en la malaltia de Parkinson [PDF]
, 2015 [cat] Les mutacions del gen PARK2 estan associades amb l‘aparició de parkinsonisme juvenil autosòmic recessiu (AR-JP). A través de diferents mecanismes aquestes mutacions comporten la pèrdua de la funció E3 lligasa de la proteïna parkina, amb el que ...
Romaní Aumedes, Joan
core +1 more source
Non‐Histone Lactylation: A New Frontier in Cerebral Ischemia‐Reperfusion Injury
Med Research, EarlyView.ABSTRACT Reperfusion therapy is the mainstay of treatment for ischemic stroke (IS) but frequently exacerbates secondary injury. Following cerebral ischemia and hypoxia, lactate accumulates markedly. Traditionally regarded as a metabolic byproduct, lactate has gained new significance with the discovery of protein lactylation. In addition to experimental
Minghui Tang +13 more
wiley +1 more source
Characterization of Vesicular Monoamine Transporter 2 and its role in Parkinson\u27s Disease Pathogenesis using Drosophila [PDF]
, 2016 Parkinson’s disease (PD) is a progressive neurodegenerative disorder caused by the selective loss of the dopaminergic neurons in the Substantia nigra pars compacta region of the brain.
Tito, Antonio Joel, Jr., Zhang, Sheng
core +1 more source
Movement Disorders, EarlyView.Abstract Background Peripheral disease mechanisms such as immune dysregulation may contribute to Parkinson's disease (PD). To investigate interactions between common PD mutations and immune responses to environmental pathogens, we studied responses to Pseudomonas aeruginosa (P.
Julian R. Mark +8 more
wiley +1 more source
What is the Ideal Monetary Policy Regime? Improving the Bank of Canada's Inflation-targeting Program [PDF]
The recent financial crisis has emphasized the role of sound monetary policy for ensuring Canada’s future prosperity. Although much is right with the Bank of Canada’s inflation-targeting regime, improvements such as price-level targeting and closer ...
Michael Parkin
core
Focused Ultrasound for the Treatment of Circuit and Molecular Pathology in Parkinson's Disease
Movement Disorders, EarlyView.Abstract Focused ultrasound is rapidly emerging as a novel technology for the development of symptomatic therapies and supporting disease‐modifying treatments for Parkinson's disease (PD). At the forefront of this development is thermoablation using high‐intensity focused ultrasound, an incisionless treatment that has been extensively tested in ...
Rikke Hahn Kofoed +7 more
wiley +1 more source